About the Rosen Lab
Our Major Research Interests:
We have established that the transcription factor PPARgamma is required for adipogenesis in vivo and in vitro, and we are now focusing on a putative "second-wave" of transcription factors that controls terminal gene expression in adipocytes. We have shown that C/EBPalpha, proposed by many to be a central regulator of adipogenesis, is actually dependent on PPARgamma for its activity. We are investigating mechanisms of lipodystrophy induced by antiretroviral therapy in AIDS.
Learn more about Dr. Evan Rosen's lab and publications below: