Warren Hill, PhD

Assistant Professor of Medicine, Harvard Medical School
WHill4CroppedThe primary research interests in Dr. Hill’s lab relate to sensory functioning of the bladder epithelium the urothelium and the role of integrins in bladder smooth muscle. The urothelium is both a barrier membrane, which limits the diffusion of urine into the underlying tissue, and a sensor, which communicates mechanical information like stretch to underlying afferent nerve fibers. The team believes that deficits in urothelial signaling may underlie diseases of the bladder, many of which manifest later in life. The lab uses genetically modified mice to investigate hypotheses related to these questions and employ a range of physiological and molecular techniques to explore the role of integrins, glycosaminoglycans, and ectonucleotidases on bladder function.

 


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