Lab Members
Principal Investigator
Warren G. Hill
whill@bidmc.harvard.edu
Tel. 617-667-5829
I have been an investigator in the field of epithelial physiology for fifteen years having completed undergraduate training at the University of Otago in New Zealand and my doctoral training at the University of Adelaide in Australia. I have published my research in a number of areas including cystic fibrosis, regulation of the epithelial sodium channel (ENaC), the function of aquaporins and urea transporters and the structure of cell membranes. Currently my research focuses on the mechanisms by which the urothelium, which lines the surface of the urinary bladder, senses filling and ultimately, fullness. Little is known about mechanosensation and mechanotransduction in the bladder and the critical pathways of molecular communication, which allow normal voiding function.
Publications by Warren Hill
Instructor
Weiqun Yu
wyu2@bidmc.harvard.edu
Tel. 617-667-5842
Dr. Yu graduated with his MD in Preventive Medicine from Zhejiang University in Hangzhou, China in 1993 and then obtained an M.S. in Bioengineering from Chongqing University, Chongqing, China in 1998. He completed his PhD. in Bioengineering at the University of Pittsburgh, Pittsburgh PA in the laboratory of Dr. Gerard Apodaca in 2008 where he studied membrane trafficking in the urothelium. He is currently an Instructor at Harvard Medical School and works with Dr. Hill on studies designed to shed light on the complex signaling pathways employed by the bladder to communicate sensory information about fullness and pain.
Research Associate
Lianyu Guo
lguo3@bidmc.harvard.edu
Tel. 617-667-1042
Lianyu Guo graduated with her PhD in Pharmacy from Seoul National University in South Korea in 2008, where she studied anti-cancer and anti-inflammatory mechanisms of natural products. She is currently a Research Associate at Beth Israel Deaconess Medical Center and works with Drs. Hill and Zeidel on studies related to mechanosignaling in the bladder. Specific projects currently include, investigations into the role of urothelial integrins in conveying sensory information about bladder filling, studies on the role of the vesicular nucleotide transporter (VNUT) in packaging and release of ATP from urothelium and studies on the role of aging in development of lower urinary tract symptoms
Research Assistant
Alexandra K. Kim
akim6@bidmc.harvard.edu
Tel. 617-667-5854
Alexandra Kim graduated with her BA in Biology with a minor in English from Wellesley College in 2013. She is currently a research assistant at Beth Israel Deaconess Medical Center and works with Dr. Hill on studies designed to shed light on the complex signaling pathways employed by the bladder to communicate sensory information about fullness and pain.
