Center for Vascular Biology Research
Furthering Research into the Vascular System
The Center for Vascular Biology Research (CVBR) is a unique community of scientist based at the Beth Israel Deaconess Medical Center (BIDMC) that studies the structure and function of the cells that comprise the vasculature. Since the vasculature plays a key role in most physiological and pathological processes, the Center’s research topics are diverse and innovative, and include: the role of angiogenesis and inflammation in different types of cancer (e.g. ovary, breast, thyroid, prostate and skin), tumor microenvironment, smooth muscle cell regulation, asthma, aging, mechanical responses of the vasculature, endothelial cell barrier function, new therapeutic and diagnostic approaches in preeclampsia, kidney disorders, sepsis, computational modeling, zebrafish models of inflammation and vessel differentiation, rare/orphan diseases, and discovery of new genetic biomarkers in organ transplantation. The results of research in these areas have been recently published in high impact journals including Nature, Nature Medicine, Nature Communications, Nature Cell Biology, Cell Stem Cell, Molecular Cell, Developmental Cell, Science Translational Medicine, Science Signaling, Science Reports, Circulation, Genes and Development, Journal of Clinical Investigation, Journal of Experimental Medicine, Proceedings of the National Academy of Sciences (USA), and Cancer Discovery.
Numerous seminars, data clubs and an annual retreat constitute the core of our educational mission. Many leading scientists who focus on drug discovery and translational research in the Boston area have participated in the research and translational seminar series this academic year. The CVBR faculty members also host a seminar series that is specifically designed for our summer students, including those funded by a T35 grant based in the Department of Surgery.