The NCPP "children" are now in their late 30s and early 40s. We are
conducting a series of adult follow-up studies, in which we locate,
recruit, and assess the parents and offspring 30 years after the original
assessments ended. In our follow-up efforts, we have successfully located
approximately 85% of the selected sample; over 90% of these subjects have
participated in interview and laboratory studies, including clinical
symptomatology, neuropsychological assessment, magnetic resonance imaging,
molecular genetics and others.
Over the past 20 years, work with the New England cohort has focused on the
prenatal and early life antecedents of a range of neuropsychiatric,
physical and behavioral conditions of late adolescence and adulthood.
Publications over the past five years have included work on schizophrenia,
substance abuse, heart disease, learning disabilities, attention deficit
disorder, depression, and suicide.
Current studies include:
Brain Function and Structure in Adults with Dyslexia and Attention
Deficit/Hyperactivity Disorder: Relationship to Obstetric Factors
Hormones and Brain function: Affective Arousal Deficits in Women with
Family Study of Psychosis: Brain, Genes, and Prenatal Risk
Neurodevelopmental Study of Schizophrenia
Prenatal/Perinatal Complications and Schizophrenia
Sex and Structural Brain Abnormalities in Schizophrenia
After the neonatal stage, the child was seen at five subsequent assessments
during childhood: ages 4 months, 8 months, 12 months, 4 years and 7 years.
Follow-up visits included pediatric, neurological and psychological
assessment of the child and maternal interviews. Follow-up rates for the
New England cohort surpassed the national project rates; over 80% of the
New England cohort completed the final full assessment at age 7.