Research Focus Areas

The Division of Experimental Pathology represents the research component of the Department of Pathology at Beth Israel Deaconess Medical Center.

Researchers in the Division of Experimental Pathology have designed in vitro and in vivo models for the characterization of pathological and physiological processes such as:

  • aging
  • asthma
  • autism
  • cancer
  • congenital diaphragmatic hernia
  • development
  • diabetes
  • epilepsy
  • ventricular arrhythmias
  • vascular diseases

Areas of Exploration

Researchers in the Department of Pathology explore the molecular and cellular mechanisms that are involved in tumor progression, angiogenesis, inflammation, and neuronal and cardiac muscle cell physiology. Ongoing studies are elucidating the molecular mechanisms that regulate the survival, migration, invasion, metastasis, and apoptosis of tumor cells, stromal fibroblasts, endothelial cells and immune cells within the tumor microenvironment.

Collaboration Encouraged

The Department of Pathology strongly encourages interactions among research and clinical faculty and provides opportunities to access a human tumor resource through its Divisions of Anatomic Pathology and Laboratory Medicine.

With the implementation of a visionary cancer program including a biorepository and robust clinical informatics, the Department of Pathology provides an exceptional environment for scientists to work in a setting that combines the strengthens of Harvard Medical School and its affiliated hospitals with an unusually collegial, supportive and interactive environment.

It is our belief that a detailed understanding of the molecular, cellular and physiological events that dictate cellular behavior will lead to novel therapeutic approaches to disease.

Laboratory Locations

  • Center for Life Sciences Building - 3 Blackfan Circle, 6th floor
  • Center for Vascular Biology, Simon C. Fireman Research North Building - 99 Brookline Avenue
  • Dana Building - 330 Brookline Avenue, 6th floor

Training Programs and Opportunities

The faculty maintains active training programs for medical and graduate students from Harvard Medical School, and postdoctoral PhD and MD research fellows. Some of these positions are supported by an NIH funded Training Program in Angiogenesis and Inflammation.

Students and fellows who are interested in the training opportunities in the Division of Experimental Pathology should contact specific faculty members or Dr. Jack Lawler, Department of Pathology, Beth Israel Deaconess Medical Center, 99 Brookline Ave., RN 270K, Boston, MA 02215.

Corporate Partnership and Donations

The Division of Experimental Pathology is highly committed to advancing health care through basic research and the development of novel therapeutics. Corporate partnership and philanthropic donations are essential parts of this mission. For further information on how we can work together, please contact Dr. Jack Lawler, Department of Pathology, Beth Israel Deaconess Medical Center, 99 Brookline Ave., RN 270K, Boston, MA 02215.