Orthopaedics Research

Orthopaedic Research at BIDMC

The Center for Advanced Orthopaedic Studies (CAOS) and the Musculoskeletal translational Innovation Initiative (MTII) at Beth Israel Deaconess Medical Center consist of 6 full-time principal investigators and additional clinician-scientists who collaborate with laboratory-based investigators. Collectively, the two research arms of the department accommodate approximately 50 researchers, including post-doctoral and research fellows, undergraduate and graduate students.

Meet our Investigators 

Our Expertise

  • Animal models of musculoskeletal disease
  • Cell and molecular biology
  • Fracture risk prediction
  • Mechanical testing
  • Non-invasive assessment of musculoskeletal tissues by micro-computed tomography and related techniques

These techniques are applied to several research areas, including:

  • Bone biomechanics
  • Bone biology
  • Spine biomechanics
  • Gene therapy of arthritis and other joint diseases
  • Regeneration and repair of bone and cartilage
  • Skeletal fragility as a result of osteoporosis and osteolytic tumors
  • Sports medicine and shoulder biomechanics

We intend to build upon these strengths and develop a fully integrated, multi-disciplinary center with research spanning from basic, bench-top studies to clinical trials.

Our Research Facilities

  • General purpose laboratory and preparatory room
  • Micro-computed tomography laboratory
  • Mechanical testing laboratory
  • Cell and molecular biology laboratories
  • An adjacent BIDMC facility for housing small animals greatly facilitates animal studies

Nazarian Laboratory

The Nazarian Laboratory fosters and promotes innovative solutions for the care of musculoskeletal diseases. Visit our website to learn more.