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The Clinical Neurophysiology fellowship at Beth Israel Deaconess Medical Center and Boston Children’s Hospital has been one of the premier training programs since its inception. This one-year ACGME-accredited fellowship provides a broad exposure and strong foundation for adult and pediatric neurologists. Fellows participate in one of four “major” subspecialty tracks:
There will be exposure to a variety of other subspecialties, and in fact 20% of the fellowship year is spent in a “minor” subspecialty area. Elective rotations in related fields, such as sleep and intraoperative neurophysiological monitoring, are also available and may be arranged at other Harvard-affiliated teaching hospitals to meet individual learning goals. Successful completion of the ACGME-accredited year will qualify graduates to take the Clinical Neurophysiology board certification exam from the American Board of Psychiatry and Neurology. For those applicants interested in two years of fellowship training, the Clinical Neurophysiology fellowship year may be combined with the Epilepsy fellowship year (see below).
The Adult EEG/Epilepsy Track of the Clinical Neurophysiology fellowship program offers focused training in various aspects of advanced clinical epileptology and electroencephalography. This is achieved through the following major rotations at BIDMC: the Epilepsy Monitoring Unit, continuous EEG monitoring in the ICU and epilepsy inpatient consultations, outpatient epilepsy clinic, and elective rotations (20%) in one of the following subspecialties: clinical neuromuscular disease with EMG/NCS, sleep, autonomic neurophysiology, and intraoperative neurophysiological monitoring. Some electives may be taken at Boston Children’s Hospital and Massachusetts General Hospital. Formal weekly teaching sessions at BIDMC include clinical neurophysiology didactic lectures, epilepsy didactic lectures, multidisciplinary surgical case conference, journal club, and EEG case review.
This Epilepsy fellowship at Beth Israel Deaconess Medical Center and Boston Children’s Hospital offers advanced clinical epilepsy training in both an inpatient and outpatient setting at these two premier institutions. This one-year ACGME-accredited fellowship provides a broad exposure and strong foundation for adult and pediatric neurologists. This is achieved through major rotations at BIDMC including the Epilepsy Monitoring Unit, epilepsy inpatient consultations, and outpatient epilepsy clinic, as well as through rigorous experiences in EEG interpretation. Successful completion of the ACGME-accredited year will quality graduates to take the Epilepsy board certification exam from the American Board of Psychiatry and Neurology. Adult Epilepsy fellows will be based primarily at BIDMC, with elective clinical epilepsy rotations at Boston Children’s Hospital.
Comprehensive Epilepsy Program
The Comprehensive Epilepsy Program at Beth Israel Deaconess Medical Center (BIDMC) in Boston has been one of the preeminent clinical centers in the United States for the diagnosis and treatment of patients with seizures ever since it was established about 40 years ago. BIDMC has been designated a Level 4 center by the National Association of Epilepsy Centers, signifying the highest level of care available in the field.
BIDMC is at the forefront of the latest technological advances for seizure patients. As a leader in the treatment of seizure disorders and related diagnoses, the BIDMC Epilepsy Program includes multiple centers and clinics for more specialized care including: a First Seizure Clinic, a Women’s Health and Epilepsy program, and the most advanced therapeutic options for patients with drug-resistant epilepsy.
We are also the home of the Berenson-Allen Center for Noninvasive Brain Stimulation, a world leader in the development of brain modulation techniques that do not require surgery. We are one of the pioneers in the cutting-edge field of critical care EEG and offer the ability to perform continuous monitoring of brain function in patients who need intensive care.
BIDMC's Epilepsy Program staff includes board-certified epileptologists, neurosurgical specialists in epilepsy-related surgical procedures, clinical neuropsychologists, neuropsychiatrists, social workers, and clinical epilepsy nurses. Staff members also collaborate with BIDMC's Cognitive Neurology Division, Neuroendocrinology, Neuroradiology, and Obstetric/Gynecology and specialists in Maternal Fetal Medicine.
Research has always been central to the experience of the adult epilepsy/EEG fellows at BIDMC. The history of the program is grounded in a number of “firsts” in the field of epilepsy, particularly in neuroimaging, antiepileptic drug trials, and EEG technology. Currently our research portfolio comprises several broad areas: 1) basic and translational science, aimed at understanding the underlying causes of epilepsy; 2) clinical research, including both investigator-initiated projects and drug and device trials; 3) technology and innovation, particularly in high-density EEG and noninvasive brain stimulation methods; 4) computational research, using large datasets to investigate the natural history of epilepsy and the results of randomized controlled trials; and 5) outcomes and quality research, exemplified by our leadership in national consortia and networks. Adult epilepsy/EEG fellows are introduced to the wide variety of possible research projects available for them when they begin their fellowship, and are linked to research mentors at BIDMC or neighboring institutions depending on their interests.
Opportunities for Teaching
BIDMC takes pride in providing prominent teaching opportunities for those fellows interested in education, involving medical students at Harvard Medical School (HMS) and neurology residents in the BIDMC-Children’s residency program. Formal training in teaching is also offered through the academies of educators at HMS and BIDMC, the Harvard-Macy Institute, additional fellowship programs in medical education, and formal master’s degree programs, for those interested in a career in education.
Clinical Neurophysiology and Epilepsy Fellowship Application Information
All interested individuals must have completed an ACGME-accredited residency training program in either pediatric or adult neurology or a program in one of these specialties that is located in Canada and accredited by the RCPSC. Selected fellows will spend 1-2 years developing subspecialty expertise in clinical neurophysiology and epilepsy.
All interested candidates should submit the following documentation:
Autonomic impairments occur in many medical conditions, as well as central
and peripheral neurologic disorders. This fellowship offers extensive
clinical training in autonomic disorders, autonomic testing and autonomic
neurophysiology. If interested, the opportunity exists to acquire skills
for skin biopsy assessment of sensory and autonomic nerves.
This fellowship was pioneered by Dr. Roy Freeman in 1996 and was one of the
first autonomic fellowships in the country. It is the only fellowship in
autonomic disorders in Massachusetts. During training, fellows will learn
the treatment and management of patients with:
Multiple system atrophy
Parkinson’s disease with dysautonomia
Pure autonomic failure
Lewy body disease
Postural tachycardia syndrome
Diabetic and other peripheral and autonomic neuropathies
Small fiber neuropathy
These conditions are often unrecognized and may be challenging to treat,
resulting in vastly underserved patient populations. The Autonomic
Fellowship at BIDMC provides outstanding clinical training, preparing
neurologists to treat all of these disorders with an interdisciplinary
This fellowship is part of a comprehensive BIDMC/Boston Children’s Hospital
Clinical Neurophysiology fellowship program that provides training in all
aspects of clinical neurophysiology. Fellows in this program participate in
a jointly shared interdisciplinary neurophysiology lecture series. This
also helps to establish a collaborative relationship with future
colleagues. Additional training is also available in EMG/NCS, EEG and sleep
disorders. This fellowship is heavily clinically based in the outpatient
setting, but there are numerous opportunities for basic, clinical and
translational research. Fellows are encouraged to pursue these and faculty
mentorship is well established.
A fellowship position is available for board certified or board eligible
adult or pediatric neurologists. This fellowship is part of a one-year
ACGME approved fellowship with board certification eligibility in clinical
Applicants interested in applying should send a letter of their career
goals and objectives as well as a curriculum vitae and three letters of
Roy Freeman, MD
Center for Autonomic and Peripheral Nerve Disorders
Department of Neurology
Beth Israel Deaconess Medical Center
185 Pilgrim Rd.
Boston, MA 02215
Roy Freeman, MD
Professor of Neurology Director, Autonomic Fellowship
Christopher Gibbons, MD,
Associate Professor of Neurology
President, American Autonomic Society
Chair, American Academy of Neurology, Autonomic Section
Alexandra Hovaguimian, MD, Instructor in Neurology
Istvan Bonyhay, MD, PhD, Instructor of Neurology
Ben Illigens, MD, Instructor in Neurology
Ningshan Wang, PhD, Instructor in Neurology
Ahmad Abuzinadah, MD
Abuzinadah graduated from King Abdulaziz University Medical school and had
his neurology training at University of Calgary, where also received his
Master's degree in medical education. He then moved to Kansas City, where
he finished neuromuscular and clinical neurophysiology training at Kansas
University and also received his degree in clinical and translational
research. Abuzinadah has been named an Assistant Professor of Neurology at
King Abdulaziz University in Jeddah, Saudi Arabia, where he plans to start
a neuromuscular and autonomic program with both clinical and research
Dong In Sinn, MD
Dong In Sinn received his medical degree and Master's degree of medical
science at Seoul National University College of Medicine in South Korea. He
trained in neurology at Seoul National University Hospital and Medical
University of South Carolina. Upon completion of his training at BIDMC, he
will join the Stanford autonomic disorders program as a clinical assistant
2003-2004: Christopher Gibbons, MD
Associate Professor of Neurology, BIDMC
Development of novel biomarkers for autonomic and peripheral
Characterization and treatment of diabetic and autonomic neuropathies.
2004-2005: Danielle Cherdak, MD
Assistant Professor of Neurology, Vanderbilt University
2015-2016: Dong-In Sinn, MD
Clinical Fellow in Neurology
Learning autonomic testing and skin biopsy evaluation of
intra-epidermal nerve fiber density
2015-2016: Ahmad Abuzinadah, MD
Clinical Fellow in Neurology
Learning autonomic testing and skin biopsy evaluation of
intra-epidermal nerve fiber density
2006: Ningshan Wang, PhD
Instructor in Neurology, Harvard Medical School
Development of novel immunohistochemical techniques for study of
autonomic and peripheral nerve disorders
2006: Ben Illigens, MD
Instructor in Neurology, Harvard Medical School
Study of autonomic neurophysiology in health and disease
2012-2014: Jenniffer Garcia, MD
Research Fellow in Neurology
Study of autonomic function research techniques, study design and
2013-2014: Eun Hee Son, MD
Research Fellow in Neurology
Evaluation of intra-epidermal nerve fiber density
Study of cutaneous autonomic neurovascular structure and function
2015-2016: Bum Chun Suh, MD
Research Fellow in Neurology
Study of cutaneous autonomic neurovascular structure and function in
health and diabetes
2015-2016: Marcel Casasola, MD
Research Fellow in Neurology
Study of diabetic neuropathy, autonomic neuropathy and
Gibbons CH, Garcia J, Wang N, Shi L, Freeman R The diagnostic
discrimination of cutaneous alpha-synuclein deposition in Parkinson
disease. Neurology (In press)
Ziegler D, Low P, Freeman R, Tritschler H, Vinik A. Predictors of
improvement and progression of diabetic polyneuropathy following
treatment with α-lipoic acid for 4 years in the NATHAN 1 trial. Journal
of Diabetes and Its Complications (In press)
Rao A, Bonyhay I, Dankwa, J; Baimas-George, M; Kneen, L; Ballatori, S;
Freeman, R*; Adler, G*. Baroreflex Sensitivity Impairment During
Hypoglycemia – Implications for Cardiovascular Control. Diabetes
Diabetes. 2016; 65(1):209-15. PMID: 26438610 PMCID: PMC4686952
Freeman R, Emir B, Parsons B. Predictors of placebo response in
peripheral neuropathic pain: insights from pregabalin clinical trials.
J Pain Res. 2015;8:257-68 [PMID: 26082659]
Gibbons C, Freeman R. Clinical implications of delayed orthostatic
hypotension – a 10 year follow up study. Neurology 2015;85:1362-1367.
Biaggioni I, Freeman R, Mathias CJ, Low PA, Hewitt A, Kaufmann H.
Randomized-withdrawal study of patients with symptomatic neurogenic
orthostatic hypotension responsive to droxidopa. Hypertension.
2015;65:101-7. [PMID: 25350981]
Gibbons C, Freeman R. Treatment induced neuropathy of diabetes: an
acute, iatrogenic complication of diabetes. Brain. 2015; 138:43-52.
Freeman R. Wallace Mark S, Sweeney M, Backonja MM. Relationships among
pain quality, pain impact, and overall improvement in patients with
postherpetic neuralgia treated with gastroretentive gabapentin. Pain
Medicine. 2015 (In press). [PMID:26115203]
Kaufmann H, Freeman R, Biaggioni I, Low PA, Pedder S, Hewitt A, Mauney
J, Feirtag M, and Mathias CJ. Droxidopa for neurogenic orthostatic
hypotension: a randomized, placebo- controlled Phase 3 trial. Neurology
2014: 83:328-35. [PMCID:PMC4115605]
Low PA, Robertson D, Gilman S, Kaufmann H, Singer W, Biaggioni I,
Freeman R, Perlman S, Hauser RA, Cheshire W, Lessig S, Vernino S,
Mandrekar J, Dupont WD, Chelimsky T, Galpern WR. Efficacy and safety of
rifampicin for multiple system atrophy: a randomized, double-blind,
placebo-controlled trial. Lancet Neurology. 2014;13:268-75.
Gibbons CH, Bonyhay I, Benson A, Wang N, Freeman R. Structural and
Functional Small Fiber Abnormalities in the Neuropathic Postural
Tachycardia Syndrome. PLoS One 2013; 8(12): e84716.
Freeman R, Baron R, Bouhassira D, Cabrera J, Birol E. Sensory profiles
of patients with neuropathic pain based on the neuropathic pain
symptoms and signs. Pain 2014;155:367-76. [PMID: 244725]
Wang N, Gibbons CH, Lafo J, Freeman R. Alpha-synuclein in cutaneous
autonomic nerves. Neurology. 2013; 81:1604-10. [PMCID: PMC3806913]
Bonyhay I, Risk M, Freeman R. High-Pass Filter Characteristics of the
Baroreflex – A Comparison of Frequency Domain and Pharmacological
Methods. PLoS One 2013; 8(11): e79513.
Gibbons CH, Freeman R, Tecilazich F, Dinh T, Lyons TE, Gnardellis C,
Veves A. The evolving natural history of neurophysiologic function in
patients with well-controlled diabetes. J Peripher Nerv Syst. 2013;
18:153-61. [PMID: 23781962]
Zhang L, Rainka M, Freeman R, Harden RN, Bell CF, Chen C, Graff O,
Harding K, Hunter S, Kavanagh S, Laurijssens B, Schwartzbach C, Warren
S, McClung C. A randomized, double-blind, placebo-controlled trial to
assess the efficacy and safety of gabapentin enacarbil in subjects with
neuropathic pain associated with postherpetic neuralgia (PXN110748).
Journal of Pain. 2013; 14:590-603. [PMID: 23602345]
Harden RN, Freeman R, Rainka M, Zhang L, Bell C, Berges A et al. A
Phase 2a, randomized, crossover trial of gabapentin enacarbil for the
treatment of postherpetic neuralgia in gabapentin inadequate
responders. Pain Medicine 2013; 12:1918-32. [PMID: 24102928]
Gibbons CH, Adler GK, Bonyhay I, Freeman R. Experimental hypoglycemia
is a human model of stress-induced hyperalgesia. Pain 2012; 153:
Siepmann T, Gibbons CH, Illigens B, Lafo JA, Brown CM, Freeman R.
Quantitative Pilomotor Axon-Reflex Test – A Novel Test of Pilomotor
Function. Arch Neurol. 2012; 69:1488-92 [PMCID: PMC3563419].
Kaufmann H, Malamut R; Norcliffe-Kaufmann L; Rosa R; Freeman R. The
Orthostatic Hypotension Questionnaire (OHQ): validation of a novel
symptom assessment scale. Clinical Autonomic Research 2011; 1-12.
Gibbons CH, Centi J, Vernino S, Freeman R. Autoimmune autonomic
ganglionopathy with reversible cognitive impairment. Arch Neurol.
2012;69:461-466 [PMCID: PMC3359761].
Ziegler D, Low PA, Litchy WJ, Boulton AJ, Vinik AI, Freeman R,
Samigullin R, Tritschler H, Munzel U, Maus J, Schütte K, Dyck PJ.
Efficacy and safety of antioxidant treatment with α-lipoic acid over 4
years in diabetic polyneuropathy: The NATHAN 1 Trial. Diabetes Care
Wang N, Gibbons CH, Freeman R. Novel immunohistochemical techniques
using discrete signal amplification systems for human cutaneous
peripheral nerve fiber imaging. Journal of Histochemistry &
Cytochemistry. 2011;59:382-90 [PMCID: PMC3201146].
Gibbons C, Wang N, Freeman R. Capsaicin induces degeneration of
cutaneous autonomic nerve fibers. Annals of Neurology 2010;68:888-98.
Gibbons C, Freeman R, Veves A. Diabetic Neuropathy: A cross sectional
study of the relationships among test of neurophysiology. Diabetes Care
Adler GK, Bonyhay I, Curren V, Waring E, Freeman R. Hypoglycemia
increases aldosterone in a dose-dependent fashion. Diabetic Medicine
Gibbons C, Freeman R. Treatment Induced Diabetic Neuropathy: A
reversible painful autonomic neuropathy. Annals of Neurology. 2010;
Simpson DM, Schifitto, G, Clifford DB, Murphy, TK, Durso-De Cruz E,
Glue P, Whalen E, Emir E, Scott, G, Freeman R. Pregabalin for painful
HIV neuropathy: a randomized, double-blind, placebo-controlled trial.
Gibbons C, Illigens B, Wang N, Freeman R. The quantification of
sudomotor innervation: a comparison of 3 methods. Muscle and Nerve.
Adler GK, Bonyhay I, Waring E, Failing HJ, Dotson S, Freeman R.
Antecedent hypoglycemia impairs autonomic cardiovascular function –
implications for rigorous glycemic control. Diabetes 2009;58:1-8.
Edwards RR, Dworkin R, Turk D, Angst M, Dionne R, Freeman R, Hansson P,
Haroutounian S, Arendt-Nielsen L, Attal N, MD et al. Patient
phenotyping in clinical trials of chronic pain treatments: IMMPACT
recommendations. Pain 2016 (In Press)
Taylor AM, Phillips K, Patel KV, Turk D, Dworkin RH, Beaton D, Clauw
DJ, Gignac MAM, Markman JD, Williams DA, Bujanover S, Burke LB, Carr
DB, Choy EH. et al. Assessment of physical function and participation
in chronic pain clinical trials: IMMPACT/OMERACT recommendations. Pain
2016 (In Press).
Finnerup NB, Haroutounian, S, Kamerman P, Baron R, Bennett DLH,
Bouhassira D, Cruccu G, Freeman R, Hansson P, Nurmikko T, Raja S, Rice
ASC; Serra J, Smith BH, Treede R-D,; Jensen TS. Neuropathic pain: An
updated grading system for research and clinical practice. Pain 2016
Dineen J. Freeman R. Autonomic Peripheral Neuropathy. Seminars in
Neurology 2015; 35: 458-468.
Freeman R, Barosso F. Familial amyloid polyneuropathy. Current Opinion
in Neurology 2016 (in Press)
van Hecke O, Kamerman P, Attal N, Baron R, Bjornsdottir G, Bennett DL,
Bennett MI, Bouhassira D, Diatchenko L, Freeman R, Freynhagenk R,
Haanpääm M, Jensen TS, Raja SN, Rice ASC, Seltzer Z, Yarnitsky D, Smith
BH. Neuropathic pain phenotyping by international consensus
(NeuroPPIC): a NeuPSIG systematic review, Delphi survey and expert
panel recommendations. Pain 2015;156:2337-53.PMID: 2646932
Laurens B, Constantinescu R, Freeman R, Gerhard A, Jellinger K, Jeromin
A, Krismer F, Mollenhauer B, Schlossmacher MG, Shaw LM, Verbeek MM,
Wenning GK, Winge K, Zhang J, Meissner WG. Fluid biomarkers in multiple
system atrophy: A review of the MSA Biomarker Initiative. Neurobiol
Dis. 2015;80:29-41. [PMID: 25982836]
Freeman R. Syncope. In Harrison’s Principles of Internal Medicine.
Nineteenth Edition. McGraw Hill Medical. 2015.
Freeman R. The puzzle of orthostatic tolerance in hereditary sensory
and autonomic neuropathy, type IV. Ann Neurol. 2015; 77:741-2. [PMID:
Freeman R. Diabetic autonomic neuropathy. Handbook of Clinical
Neurology. 2014;126:63-79. [PMID: 25410215]
Höke A, Simpson DM, Freeman R. Designing innovative therapies for
neuropathic pain: preclinical and early clinical development
challenges. J Peripher Nerv Syst. 2014: Suppl 2:S28-9. PMID:25269739
Fillingim, R.B., Bruehl, S., Dworkin, R.H., Dworkin, S.F., Loeser,
J.D., Turk, D.C., Widerstrom-Noga, E., Arnold, L., Bennett, R.,
Edwards, R.R., Freeman, R., Gewandter, J., Hertz, S., Hochberg, M.,
Krane, E., Mantyh, P.W., Markman, J., Neogi, T., Ohrbach, R., Paice,
J., Porreca, F., Rappaport, B.A., Smith, S.M., Smith, T.J., Sullivan,
M.D., Verne, G.N., Wasan, A.D. & Wesselmann, U. The
ACTTION-American Pain Society Pain Taxonomy (AAPT): An evidence-based
and multi-dimensional approach to classifying chronic pain conditions.
J Pain. 2014;15:241-9. [PMID: 2458163]
Gibbons C, Cheshire W, Barboi A, Levine B, Olshansky B, Kinsella L,
Claydon VE, Crandall C, Fink G, Joyner M, Macefield V,
Norcliffe-Kaufmann L, Freeman R, Raj S, Stewart J, Sandroni P, Kaufmann
H, Chelimsky T. Endovascular procedures for the treatment of autonomic
dysfunction. Clin Auton Res. 2014;24:1-2. PMID: 24178965
Höke A, Simpson DM, Freeman R. Challenges in developing novel therapies
for peripheral neuropathies. J Peripher Nerv Syst. 2013; 18:1-6. [PMID:
Freeman R. New and developing drugs for the treatment of pain in
diabetic peripheral neuropathy. Curr Diab Rep. 2013;13:500-8 [PMID:
Emir B, Amaratunga D, Beltangady M, Cabrera J, Freeman R, Madigan D,
Nguyen H, Whalen E. Generating productive dialogue between consulting
statisticians and their clients in the pharmaceutical and medical
research settings. Open Access Medical Statistics. 2013:3 51–56
Schestatsky P, Simis M, Freeman R, Pascual-Leone A, Fregni F.
Non-invasive brain stimulation and the autonomic nervous system. Clin
Neurophysiol. 2013; 124:1716-28. [PMID: 23684898]
Backonja MM, Attal N, Baron R, Bouhassira D, Drangholt M, Dyck PJ,
Edwards RR, Freeman R, Gracely R, Haanpaa MH, Hansson P, Hatem SM,
Krumova EK, Jensen TS, Maier C, Mick G, Rice AS, Rolke R, Treede RD,
Serra J, Toelle T, Tugnoli V, Walk D, Walalce MS, Ware M, Yarnitsky D,
Ziegler D. Value of quantitative sensory testing in neurological and
pain disorders: NeuPSIG consensus. Pain. 2013; 154:1807-19.
Freeman R, Chapleau MW. Testing the autonomic nervous system. Handbook
of Clinical Neurology. 2013; 115: 115-36.
Freeman R. Objective evidence of autonomic dysfunction and the role of
stress in the Gulf War syndrome. JAMA Neurol. 2013;70:158-9. doi:
10.1001/jamaneurol.2013.1494. PMID: 23407742
Freeman R. Pharmacotherapy of Neuropathic Pain. In: Simpson DM,
McArthur JCM, Dworkin R, Editors. Neuropathic Pain: Mechanisms and
Management. Oxford University Press. New York, NY. 2012.
Freeman R. Autonomic Peripheral Neuropathy. In Donofrio PD (ed)
.Textbook of Peripheral Neuropathy Chapter 28 (421-438). Demos Medical
(New York) 2012.
Gibbons CH, Freeman R. Cutaneous autonomic innervation – Assessment by
skin biopsy In: Robertson D, , Biaggioni I, Burnstock G , Low PA, Paton
JFR eds. Primer on the Autonomic nervous system. 3nd Edition. Academic
Press, New York, 2011; 85:413-417.
Gibbons CH, Freeman R. Delayed orthostatic hypotension. In: Robertson
D, , Biaggioni I, Burnstock G, Low PA, Paton JFR eds. Primer on the
Autonomic nervous system. 3nd Edition. Academic Press, New York, 2011;
Kempler P, Amarenco G, Freeman R, Frontoni S, Horowitz M, Stevens M,
Low P, Pop-Busui R, Tahrani A, Tesfaye S, Várkonyi T, Ziegler D,
Valensi P; on behalf of the Toronto Consensus Panel on Diabetic
Neuropathy. Gastrointestinal autonomic neuropathy, erectile-, bladder-
and sudomotor dysfunction in patients with diabetes mellitus: clinical
impact, assessment, diagnosis, and management. Diabetes Metab Res Rev.
Spallone V, Ziegler D, Freeman R, Bernardi L, Frontoni S, Pop-Busui R,
Stevens M, Kempler P, Hilsted J, Tesfaye S, Low P, Valensi P; on behalf
of the Toronto Consensus Panel on Diabetic Neuropathy. Cardiovascular
autonomic neuropathy in diabetes: clinical impact, assessment,
diagnosis, and management. Diabetes Metab Res Rev. 2011 (Epub)
Bernardi L, Spallone V, Stevens M, Hilsted J, Frontoni S, Pop-Busui R,
Ziegler D, Kempler P, Freeman R, Low P, Tesfaye S, Valensi P; on behalf
of the Toronto Consensus Panel on Diabetic Neuropathy. Investigation
methods for cardiac autonomic function in human research studies.
Diabetes Metab Res Rev. 2011 (Epub)
Freeman R, Wieling W, Axelrod FB, Benditt DG, Benarroch E, Biaggioni I,
Cheshire WP, Chelimsky T, Cortelli P, Gibbons CH, Goldstein DS,
Hainsworth R, Hilz MJ, Jacob G, Kaufmann H, Jordan J, Lipsitz LA,
Levine BD, Low PA, Mathias C, Raj SR, Robertson D, Sandroni P, Schatz
I, Schondorff R, Stewart JM, van Dijk JG. Consensus statement on the
definition of orthostatic hypotension, neurally mediated syncope and
the postural tachycardia syndrome. Autonomic Neuroscience – Basic and
Tesfaye S, Boulton AJ, Dyck PJ, Freeman R, Horowitz M, Kempler P,
Lauria G, Malik RA, Spallone V, Vinik A, Bernardi L, Valensi P; Toronto
Diabetic Neuropathy Expert Group. Diabetic neuropathies: update on
definitions, diagnostic criteria, estimation of severity, and
treatments. Diabetes Care. 2010;33:2285-93.
Freeman R. Syncope. Chapter 20. In Harrison’s Principles of Internal
Medicine. Eighteenth Edition. McGraw Hill Medical. 2011
In the CNP fellowship, fellows spend the majority of their time developing
EMG expertise in addition to rotation to other areas of clinical
neurophysiology, including EEG, autonomic disorders, and sleep.
Patient care is a critical part of the fellowship and fellows spend
approximately two half-days participating in our outpatient Neuromuscular
Clinic, where they have the opportunity to diagnose and manage patients
with a variety of neuromuscular disorders, in addition to providing
inpatient neuromuscular and electrodiagnostic consultations. This
experience is further enhanced through participation in the
multidisciplinary Motor Neuron Disorders clinic.
There are opportunities to learn skin biopsy procedures for intraepidermal
nerve fiber (IENF) quantitative analysis. Opportunities for research are
also available and participation in a project during the year is strongly
encouraged. Formal didactics include weekly neuromuscular and clinical
neurophysiology teaching conferences. Fellows who successfully complete
this fellowship are eligible for the American Board of Psychiatry and
Neurology Subspecialty qualification in Clinical Neurophysiology.
Contact Dr. Elizabeth Raynor for more information about the CNP/EMG focus
fellowship at BIDMC:
In this fellowship, as in the CNP fellowship, there is extensive training
in performance and interpretation of electrodiagnostic studies (EMG), as
well as the evaluation and management of neuromuscular disorders. In
addition to EMG and Neuromuscular clinic sessions weekly, there is a
half-day spent in pediatric Neuromuscular/MDA clinic at Boston Childrens
As for the CNP fellows, there are opportunities to learn skin biopsy
procedures for IENF; additionally, there are opportunities to observe
muscle and nerve biopsies and attend a weekly multi-center muscle biopsy
conference. All fellows attend the weekly Neuromuscular conference and
participate in multidisciplinary Motor Neuron Disorders clinic. Clinical
and translational research projects are strongly encouraged. Fellows who
successfully complete this fellowship are eligible for the American Board
of Psychiatry and Neurology Subspecialty qualification in Neuromuscular
Eligibility & Application
Applicants must have successfully completed an ACGME-accredited program in
neurology, child neurology or a program in one of these specialties that is
located in Canada and accredited by the RCPSC. Fellows must provide
verification of their level of competency in neurology or child neurology
using ACGME or CanMEDS Milestones assessments from the core residency
Contact Dr. Aimee Boegle for more information about the Neuromuscular
Medicine Fellowship at BIDMC:
Seward Rutkove, MD, Chief, Division of Neuromuscular Disorders
Elizabeth Raynor, MD, Associate Professor of Medicine, HMS; Director, EMG
Pushpa Narayanaswami, MD
Courtney E. McIlduff, MD
Aimee K. Boegle, MD, PhD, Director, Neuromuscular Medicine Fellowship
Boston Children’s Hospital has a longstanding, time-honored
program in clinical neurophysiology and epilepsy in conjunction
with the BIDMC fellowship. Fellows rotate between the Epilepsy
Monitoring Unit, Epilepsy Inpatient Consult/ICU/EEG service,
outpatient/ambulatory EEG service with epilepsy clinic, and
Multiple electives are available in highly selected areas with
research opportunities. These include:
Pediatric sleep disorders
A second year for focused research is often available.
Eligible candidates for the Children’s Hospital positions will
have successfully completed prerequisite residency training
with board eligibility in pediatric neurology. Please contact
Dr. Jurriaan Peters for more information.
Jurriaan Peters MD, Training Director
Division of Epilepsy & Clinical Neurophysiology
Boston Children’s Hospital
300 Longwood Avenue
Boston, MA 02115
Leadership & Core Faculty
Phillip Pearl, MD, Division Director
Tobias Loddenkemper, MD, Director of Clinical Research
Ann Poduri, MD, Director of Epilepsy Genetics
Alex Rotenberg, MD, Director of Neuromodulation
Mark Libenson, MD, Director of EEG Laboratory
Ann Bergin, MD, Director of Ketogenic Diet Program
Jurriaan Peters, MD, Director of Computational Neurophysiology
Arnold Sansevere, MD, Director of ICU Monitoring
Chellamani Harini, MD, Director of Infantile Spasms Program
Max Takeoka, MD, Neurophysiology Research
Jeffrey Bolton, MD, Epilepsy Surgery Program
Archana Patel, MD, International Neurology and Epilepsy Program