Your liver, one of the body's largest solid organs, is a factory and a
filter, performing more than 400 different functions in healthy adults. The
many metabolic disorders that can occur with liver (hepatic) failure
demonstrate the complexity of functions and the central role your liver has
in your body's metabolism for food and fuel. Click
for more information about the liver's many functions and here to view an
interactive presentation on the digestive system and the liver.
There are many diseases that can affect the liver's ability to function
Toxins, alcohol, poor diet or infection can damage the liver
Inherited disorders may affect liver function by causing harmful
substances, such as iron and copper, to collect in the liver
Viral infections, such as hepatitis A, B, C, D and E, can cause liver
cell inflammation, cell death and ultimately lead to liver destruction
Tumors in the liver or bile ducts
Liver failure occurs when the liver does not perform as it should. Chronic
liver disease is an ongoing liver injury that lasts more than six months.
Acute injury is a brief but very severe trauma to the liver that generally
resolves or takes care of itself. However, some people suffer an acute
injury that is so grave that it leads to liver failure.
Our multidisciplinary team in the Transplant and Liver Centers work
together to treat people with deteriorating liver function and
hepatobiliary disease. People benefit from medical, surgical or
interventional procedures - or a combination of all therapies - precisely
tailored for each individual.