Liver Transplantation at BIDMC
A liver transplant may be considered as a treatment option for people with advanced or
end-stage liver disease, who have deteriorating liver function and quality of
life, and who are unable to benefit from other medical and surgical treatments.
diseases can harm the liver. Some of these diseases are "acute,"
working quickly in just days or weeks, while others are "chronic" and
take years to do damage. The liver has an amazing ability to regenerate, or
make new liver tissue. However, extensive damage to liver cells - from acute or
chronic illness or injury - can lead to scarring, which can prevent tissue
Cirrhosis occurs because of chronic liver damage. Cirrhosis causes broad bands of scarring tissue to develop, and
surround, regenerating liver tissue. The progressive scarring destroys liver
cell function. Cirrhosis also impairs blood flow to the liver, so that
gradually the liver loses its ability to clean the body of toxins, manufacture
proteins and clotting substances, and process nutrients and hormones. Scar
tissue can also put pressure on the liver's portal veins, leading to portal
hypertension, or high blood pressure, within the liver. A serious condition,
portal hypertension may cause fluid to collect throughout the body, affect the
kidney and other organs, and lead to intestinal bleeding.
BIDMC Transplant Institute Meet Our Team