Selected March Publications from BIDMC Faculty

BIDMC Communications mediarelations@bidmc.harvard.edu

APRIL 06, 2022

Building on BIDMC’s culture of collaboration and innovation, our researchers are helping to transform medicine and health care delivery. Below are selected academic publications issued in the month of March.

DGAT2 inhibition potentiates lipid droplet formation to reduce cytotoxicity in APOL1 kidney risk variants
Journal of the American Society of Nephrology / Original Research / March 1, 2022
BIDMC Authors: Justin Chun, Cristian V. Riella, Shrijal S. Shah, Jose M. Magraner, Jia-Yue Zhang, Seth. L. Alper, David J. Friedman and Martin R. Pollak (Division of Nephrology)

Relations of metabolic health and obesity to brain aging in young to middle‐aged adults
Journal of the American Heart Association / Original Research / March 1, 2022
BIDMC Authors: Rebecca Angoff, Connie W. Tsao (Division of Cardiology)

The WHO safe childbirth checklist after 5 years: future directions for improving outcomes
Lancet Global Health / Perspective / March 1, 2022
BIDMC Author: Rose Molina (Department of Obstetrics and Gynecology)

Characterization of immune responses in fully vaccinated individuals following breakthrough infection with the SARS-CoV-2 delta variant
Science Translational Medicine / Original Research / March 8, 2022
BIDMC Authors: Ai-ris Y. Collier, Catherine M. Brown, Katherine A. McMahan, Jingyou Yu, Jinyan Liu, Catherine Jacob-Dolan, Abishek Chandrashekar, Jessica L. Ansel, Marjorie Rowe, Daniel Sellers, Kunza Ahmad, Ricardo Aguayo, Tochi Anioke, Sarah Gardner, Mazuba Siamatu, Lorraine Bermudez Rivera, Michele R. Hacker, Dan H. Barouch (Center for Virology and Vaccine Research, Department of Obstetrics and Gynecology)

A single-cell atlas of human and mouse white adipose tissue
Nature / Original Research / March 16, 2022
BIDMC Authors: Margo P. Emont, Christopher Jacobs, Adam L. Essene, Deepti Pant, Danielle Tenen, Gregory P. Westcott, Amrita Kar, Molly L. Veregge, Anton Gulko, Harini Srinivasan, Zachary Kramer, Erin Merkel, Jennifer Ducie, Christopher G. Boyd, Samuel J. Lin, Bernard T. Lee, Donald Morris, Adam Tobias, Amit V. Khera, Linus T. Tsai, Evan D. Rosen (Division of Endocrinology, Diabetes and Metabolism, Department of Obstetrics and Gynecology, Department of Surgery)

SARS-CoV-2 receptor binding domain displayed on HBsAg virus–like particles elicits protective immunity in macaques
Science Advances / Original Research / March 16, 2022
BIDMC Authors: Lisa H. Tostanoski, Amanda J. Martinot, Abishek Chandrashekar, Katherine McMahan, Noe B. Mercado, Jingyou Yu, Aiquan Chang, Victoria M. Giffin, Felix Nampanya, Shivani Patel, Dan H. Barouch (Center for Virology and Vaccine Research)

Neutralization of the SARS-CoV-2 Omicron BA.1 and BA.2 variants
New England Journal of Medicine / Research Letter / March 16, 2022
BIDMC Authors: Jingyou Yu, Ai-ris Y. Collier, Marjorie Rowe, Fatima Mardas, John D. Ventura, Huahua Wan, Jessica Miller, Olivia Powers, Benjamin Chung, Mazuba Siamatu, Nicole P. Hachmann, Nehalee Surve, Felix Nampanya, Abishek Chandrashekar, Dan H. Barouch (Center for Virology and Vaccine Research)

Vaccine protection against the SARS-CoV-2 Omicron variant in macaques
Cell / Original Research / March 16, 2022
BIDMC Authors: Abishek Chandrashekar, Jingyou Yu, Katherine McMahan, Catherine Jacob-Dolan, Jinyan Liu, Xuan He, David Hope, Tochi Anioke, Julia Barrett, Benjamin Chung, Nicole P. Hachmann, Michelle Lifton, Jessica Miller, Olivia Powers, Michaela Sciacca, Daniel Sellers, Mazuba Siamatu, Nehalee Surve, Haley VanWyk, Huahua Wan, Cindy Wu, Dan H. Barouch (Center for Virology and Vaccine Research)

Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b
Science Translational Medicine / Original Research / March 23, 2022
BIDMC Authors: Suraj J. Patel, Sam Piaker, Anton Gulko, Maynara L. Andrade, Frankie D. Heyward, Tyler Sermersheim, Nufar Edinger, Harini Srinivasan, Margo P. Emont, Gregory P. Westcott, Shuai Yan, Linus Tsai, Evan D. Rosen (Division of Endocrinology, Diabetes and Metabolism)

Moral distress and moral injury among attending neurosurgeons: A national survey
Neurosurgery / Original Research / March 25, 2022
BIDMC Authors: Charles E. Mackel, Ron L. Alterman, Mary K. Buss, Roger B. Davis, Martina Stippler (Department of Neurosurgery, Division of General Medicine and Primary Care)

One person
JAMA / Perspective / March 29, 2022
BIDMC Author: Wendy Stead (Division of Infectious Diseases)

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