Education and Fellowship Programs


The Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology offers two fellowships, the Smith Center Fellowship and the Spina Scholar Program. The first of its kind in Boston, the Center places the Division of Cardiovascular Medicine and BIDMC at the forefront of a field that will only become more critical in the years ahead as health care reform places a greater emphasis on providing high-quality, cost-effective care that is centered on the patient.

The Smith Center Fellowship

Jordan Strom The Smith Center offers a fellowship training program for researchers interested in studying cardiovascular outcomes. The fellowship provides early career cardiologists with an opportunity to develop the expertise and skills needed to advance their portfolio in outcomes research.

The fellow will undertake formal training at Harvard T.H. Chan School of Public Health in research methodology, develop novel research ideas, apply for grants, conduct research and publish their findings. They will be expected to submit abstracts at national and international conferences, and develop relationships within the broader research community focusing on this specialized field of research in both academia and industry.

We are pleased to welcome Jordan Strom, MD, a fellow in Cardiovascular Medicine, as the awardee of the inaugural fellowship.

The Spina Scholars Program Fellowship

Will Grandin The newly endowed Spina Scholars Program is catalyzing transformative support for the Division of Cardiology at BIDMC. The Spina Scholar will be embedded within the Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology in the Division of Cardiovascular Medicine.

This two-year scholarship will allow each recipient, typically a junior faculty member, freedom to take novel research ideas in new and exciting directions. As an academic physician-scientist with a deep understanding of clinical medicine, social policy, and epidemiologic methods, the Spina Scholar will be ideally placed to become a leader in the field of cardiovascular outcomes research.

The Spina Scholar in Cardiovascular Outcomes Research is made possible through the generous support of Stephanie and David Spina, who have created the Spina Endowment Fund, out of which the Spina Scholars in Cardiovascular Outcomes Research will be funded biannually and in perpetuity.

We are pleased to welcome Will Grandin, MD, as the inaugural Spina Scholar joining the Smith Center in July 2016.

Statistical Analysis Software

As part of our research mission, we are making some statistical software available to the research community. The following text files are R programs that can be used to perform statistical analyses for the study of heterogeneity of treatment effect using data from randomized clinical trials. The statistical theories behind these programs are described in the following publications:

  • Shen C, Li X, Jeong J. Estimation of treatment effect in a sub-population: an empirical Bayes approach. Journal of Biopharmaceutical Statistics. 2016;26:507-518.
  • Taft L, Shen C. A non-parametric statistical test of null treatment effect in sub-populations. Journal of Biopharmaceutical Statistics. 2019;15:1-17.

Test_main.R is the main function to detect heterogeneity of treatment effect.
Test_functions.R includes all functions needed for Test_main.R.
Effect_estimation_main.R is the main function to estimate treatment effect in a subgroup.
Effect_estimation_functions.R includes all functions needed for Effect_estimation_main.R.

If you have feedback or questions regarding these programs, you can reach our Statistical Director, Dr. Changyu Shen, at