Our Publications

The Division of MRI Research in the Department of Radiology at Beth Israel Deaconess Medical Center is dedicated to pursuing and sharing the latest research in the field of MR imaging. Below is a selection of recent abstracts and publications by our clinicians, clinical scientists, and basic scientists.

Esfahani SA, Callahan C, Rotile NJ, Heidari P, Mahmood U, Caravan PD, Grant AK, Yen YF. Hyperpolarized [1-13C]Pyruvate Magnetic Resonance Spectroscopic Imaging for Evaluation of Early Response to Tyrosine Kinase Inhibition Therapy in Gastric Cancer. Mol Imaging Biol. 2022 Apr 25. Doi:10.1007/s11307-022-01727-z. Epub ahead of print

Bockorny B, Bullock AJ, Abrams TA, Faintuch S, Alsop DC, Goldberg SN, Ahmed M, Miksad RA. Priming of Sorafenib Prior to Radiofrequency Ablation Does Not Increase Treatment Effect in Hepatocellular Carcinoma. Dig Dis Sci. 2022 Jul;67(7):3455-3463.

Hertanu A, Soustelle L, Le Troter A, Buron J, Le Priellec J, Carvalho VND, Cayre M, Durbec P, Varma G, Alsop DC, Girard OM, Duhamel G. T1D-weighted ihMT imaging - Part I. Isolation of long- and short- T1D components by T1D-filtering. Magn Reson Med. 2022 May;87(5):2313-2328.

Hertanu A, Soustelle L, Buron J, Le Priellec J, Cayre M, Le Troter A, Varma G, Alsop DC, Durbec P, Girard OM, Duhamel G. T1D-weighted ihMT imaging - Part II. Investigating the long- and short- T1D components correlation with myelin content. Comparison with R1 and the macromolecular proton fraction. Magn Reson Med. 2022 May;87(5):2329-2346.

Sharkey C, Long X, Wang Z, Al-Faouri R, Gershman B, Tsai LL, Olumi AF. Zonal Growth Pattern of the Prostate Is Affected by Age and Body Mass Index. J Urol. 2022 Apr;207(4):876-884.

Cahill LC, Rosen S, Yoshitake T, Wu Y, York L, Tsai LL, Gershman B, Fujimoto JG, Sun Y. Real-time diagnosis and Gleason grading of prostate core needle biopsies using nonlinear microscopy. Mod Pathol. 2022 Apr;35(4):539-548.

Wei PK, Gupta M, Tsai LL, Lee KS, Jaramillo AM, Smith MP, LeGout JD, Shenoy-Bhangle AS. Spectrum of MRI Features of Mucin-producing Neoplasms in the Abdomen and Pelvis. Radiographics. 2022 Mar-Apr;42(2):469-486.

Soustelle L, Troalen T, Hertanu A, Mchinda S, Ranjeva JP, Guye M, Varma G, Alsop DC, Duhamel G, Girard OM. A strategy to reduce the sensitivity of inhomogeneous magnetization transfer (ihMT) imaging to radiofrequency transmit field variations at 3 T. Magn Reson Med. 2022 Mar;87(3):1346-1359.

Haider M, Jiang BG, Parker JA, Bullock AJ, Goehler A, Tsai LL. Use of MRI and Ga-68 DOTATATE for the detection of neuroendocrine liver metastases. Abdom Radiol (NY). 2022 Feb;47(2):586-595.

Sprugnoli G, Munsch F, Cappon D, Paciorek R, Macone J, Connor A, El Fakhri G, Salvador R, Ruffini G, Donohoe K, Shafi MM, Press D, Alsop DC, Pascual Leone A, Santarnecchi E. Impact of multisession 40Hz tACS on hippocampal perfusion in patients with Alzheimer's disease. Alzheimers Res Ther. 2021 Dec 20;13(1):203.

Champagne AA, Wen Y, Selim M, Filippidis A, Thomas AJ, Spincemaille P, Wang Y, Soman S. Quantitative Susceptibility Mapping for Staging Acute Cerebral Hemorrhages: Comparing the Conventional and Multiecho Complex Total Field Inversion magnetic resonance imaging MR Methods. J Magn Reson Imaging. 2021 Dec;54(6):1843-1854.

Kim G, Donohoe K, Smith MP, Hamaguchi R, Johnson AR, Singhal D, Tsai LL. Use of non-contrast MR in diagnosing secondary lymphedema of the upper extremities. Clin Imaging. 2021 Dec;80:400-405.

Varma G, Seth P, Coutinho de Souza P, Callahan C, Pinto J, Vaidya M, Sonzogni O, Sukhatme V, Wulf GM, Grant AK. Visualizing the effects of lactate dehydrogenase (LDH) inhibition and LDH-A genetic ablation in breast and lung cancer with hyperpolarized pyruvate NMR. NMR Biomed. 2021 Aug;34(8):e4560.

Shinde AB, Lerud KD, Munsch F, Alsop DC, Schlaug G. Effects of tDCS dose and electrode montage on regional cerebral blood flow and motor behavior. Neuroimage. 2021 Aug 15;237:118144.

Taso M, Munsch F, Zhao L, Alsop DC. Regional and depth-dependence of cortical blood-flow assessed with high-resolution Arterial Spin Labeling (ASL). J Cereb Blood Flow Metab. 2021 Aug;41(8):1899-1911.

Goodwin JS, Tsai LL, Mwin D, Coutinho de Souza P, Dialani S, Moon JT, Zhang Z, Grant AK, Ahmed M. In vivo detection of distal tumor glycolytic flux stimulated by hepatic ablation in a breast cancer model using hyperpolarized 13C MRI. Magn Reson Imaging. 2021 Jul;80:90-97.

Kim G, Johnson AR, Hamaguchi R, Adondakis M, Tsai LL, Singhal D. Breast Cancer-Related Lymphedema: Magnetic Resonance Imaging Evidence of Sparing Centered Along the Cephalic Vein. J Reconstr Microsurg. 2021 Jul;37(6):519-523.

Schawkat K, Tsai LL, Jaramillo-Cardoso A, Paez SN, Moser JA, Decicco C, Singer T, Glickman J, Brook A, Manning MA, Mortele KJ. Use of ring-enhancement and focal necrosis to differentiate pancreatic adenosquamous carcinoma from pancreatic ductal adenocarcinoma on CT and MRI. Clin Imaging. 2021 May;73:134-138.

Ercan E, Varma G, Dimitrov IE, Xi Y, Pinho MC, Yu FF, Zhang S, Wang X, Madhuranthakam AJ, Lenkinski RE, Alsop DC, Vinogradov E. Combining inhomogeneous magnetization transfer and multipoint Dixon acquisition: Potential utility and evaluation. Magn Reson Med. 2021 Apr;85(4):2136-2144.

Xu HS, Balcacer P, Zhang Z, Zhang L, Yee EU, Sun MR, Tsai LL. Characterizing T2 iso- and hypo-intense renal masses on MRI: Can templated algorithms improve accuracy? Clin Imaging. 2021 Apr;72:47-54.

Tsai LL, Bhatt RS, Strob MF, Jegede OA, Sun MRM, Alsop DC, Catalano P, McDermott D, Robson PM, Atkins MB, Pedrosa I. Arterial Spin Labeled Perfusion MRI for the Evaluation of Response to Tyrosine Kinase Inhibition Therapy in Metastatic Renal Cell Carcinoma. Radiology. 2021 Feb;298(2):332-340.

Munsch F, Varma G, Taso M, Girard O, Guidon A, Duhamel G, Alsop DC. Characterization of the cortical myeloarchitecture with inhomogeneous magnetization transfer imaging (ihMT). Neuroimage. 2021 Jan 15;225:117442.

Moosavi B, Shenoy-Bhangle AS, Tsai LL, Reuf R, Mortele KJ. MRI characterization of focal liver lesions in non-cirrhotic patients: assessment of added value of gadoxetic acid-enhanced hepatobiliary phase imaging. Insights Imaging. 2020 Sep 22;11(1):101.

Zhao L, Taso M, Dai W, Press DZ, Alsop DC. Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling. Fluids Barriers CNS. 2020 Sep 22;17(1):58.

Nery F, Buchanan CE, Harteveld AA, Odudu A, Bane O, Cox EF, Derlin K, Gach HM, Golay X, Gutberlet M, Laustsen C, Ljimani A, Madhuranthakam AJ, Pedrosa I,Prasad PV, Robson PM, Sharma K, Sourbron S, Taso M, Thomas DL, Wang DJJ, Zhang JL, Alsop DC, Fain SB, Francis ST, Fernandez-Seara MA. Consensus-based technical recommendations for clinical translation of renal ASL MRI. MAGMA. 2020 Feb;33(1):141-161.

Mendichovszky I, Pullens P, Dekkers I, Nery F, Bane O, Pohlmann A, de Boer A, Ljimani A, Odudu A, Buchanan C, Sharma K, Laustsen C, Harteveld A, Golay X, Pedrosa I, Alsop D, Fain S, Caroli A, Prasad P, Francis S, Sigmund E, Fernandez-Seara M, Sourbron S. Technical recommendations for clinical translation of renal MRI: a consensus project of the Cooperation in Science and Technology Action PARENCHIMA. MAGMA. 2020 Feb;33(1):131-140.

Munsch F, Taso M, Zhao L, Lebel RM, Guidon A, Detre JA, Alsop DC. Rotated spiral RARE for high spatial and temporal resolution volumetric arterial spin labeling acquisition. Neuroimage. 2020 Dec;223:117371.

Varma G, Munsch F, Burns B, Duhamel G, Girard OM, Guidon A, Lebel RM, Alsop DC. Three-dimensional inhomogeneous magnetization transfer with rapid gradient-echo (3D ihMTRAGE) imaging. Magn Reson Med. 2020 Dec;84(6):2964-2980.

Kim G, Smith MP, Donohoe KJ, Johnson AR, Singhal D, Tsai LL. MRI staging of upper extremity secondary lymphedema: correlation with clinical measurements. Eur Radiol. 2020 Aug;30(8):4686-4694.

Huang CWC, Ali A, Chang YM, Bezuidenhout AF, Hackney DB, Edlow JA, Bhadelia RA. Major Radiologic and Clinical Outcomes of Total Spine MRI Performed in the Emergency Department at a Major Academic Medical Center. AJNR Am J Neuroradiol. 2020 Jun;41(6):1120-1125.

Freedman JD, Ellis DJ, Lusic H, Varma G, Grant AK, Lakin BA, Snyder BD, Grinstaff MW. dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Cadaveric Human Metacarpal Cartilage. J Orthop Res. 2020 Apr;38(4):719-725.

Soman S, Dai W, Dong L, Hitchner E, Lee K, Baughman BD, Holdsworth SJ, Massaband P, Bhat JV, Moseley ME, Rosen A, Zhou W, Zaharchuk G. Identifying cardiovascular risk factors that impact cerebrovascular reactivity: An ASL MRI study. J Magn Reson Imaging. 2020 Mar;51(3):734-747.

Taso M, Papadopoulou F, Smith MP, Tsai LL, Mortele KJ, Alsop DC. Pancreatic perfusion modulation following glucose stimulation assessed by noninvasive arterial spin labeling (ASL) MRI. J Magn Reson Imaging. 2020 Mar;51(3):854-860.

Racine AM, Touroutoglou A, Abrantes T, Wong B, Fong TG, Cavallari M, Travison TG, Gou Y, Marcantonio ER, Alsop DC, Jones RN, Inouye SK, Dickerson BC; SAGES study group. Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline After Surgery. J Alzheimers Dis. 2020;75(1):187-199.

Carvalho VND, Hertanu A, Grelard A, Mchinda S, Soustelle L, Loquet A, Dufourc EJ, Varma G, Alsop DC, Thureau P, Girard OM, Duhamel G. MRI assessment of multiple dipolar relaxation time (T1D) components in biological tissues interpreted with a generalized inhomogeneous magnetization transfer(ihMT) model. J Magn Reson. 2020 Feb;311:106668.

Dai W, Chen M, Duan W, Zhao L, Bolo NR, Tamminga C, Clementz BA, Pearlson GD, Alsop DC, Keshavan M. Abnormal perfusion fluctuation and perfusion connectivity in bipolar disorder measured by dynamic arterial spin labeling. Bipolar Disord. 2020 Jun;22(4):401-410.

Beker K, Lee KS, Tsai LL, Hegazi T, Garces-Descovich A, Brook A, Mortele KJ. Differentiation of pancreatic head ductal adenocarcinoma from inflammatory pancreatic pseudomass by MR cholangio-pancreatography: utility of the duct-interrupted, corona, and attraction signs. Abdom Radiol (NY). 2019 Dec;44(12):4048-4056.

Duhamel G, Prevost VH, Cayre M, Hertanu A, Mchinda S, Carvalho VN, Varma G, Durbec P, Alsop DC, Girard OM. Validating the sensitivity of inhomogeneous magnetization transfer (ihMT) MRI to myelin with fluorescence microscopy. Neuroimage. 2019 Oct 1;199:289-303.

Taso M, Guidon A, Alsop DC. Influence of background suppression and retrospective realignment on free-breathing renal perfusion measurement using pseudo-continuous ASL. Magn Reson Med. 2019 Apr;81(4):2439-2449.

Taso M, Guidon A, Zhao L, Mortele KJ, Alsop DC. Pancreatic perfusion and arterial-transit-time quantification using pseudocontinuous arterial spin labeling at 3T. Magn Reson Med. 2019 Jan;81(1):542-550.

Taso M, Zhao L, Guidon A, Litwiller DV, Alsop DC. Volumetric abdominal perfusion measurement using a pseudo-randomly sampled 3D fast-spin-echo (FSE)arterial spin labeling (ASL) sequence and compressed sensing reconstruction. Magn Reson Med. 2019 Aug;82(2):680-692.

Fischl AS, Wang X, Falcon BL, Almonte-Baldonado R, Bodenmiller D, Evans G, Stewart J, Wilson T, Hipskind P, Manro J, Uhlik MT, Chintharlapalli S, Gerald D, Alsop DC, Benjamin LE, Bhatt RS. Inhibition of Sphingosine Phosphate Receptor 1 Signaling Enhances the Efficacy of VEGF Receptor Inhibition. Mol Cancer Ther. 2019 Apr;18(4):856-867.

Zhao L, Alsop DC, Detre JA, Dai W. Global fluctuations of cerebral blood flow indicate a global brain network independent of systemic factors. J Cereb Blood Flow Metab. 2019 Feb;39(2):302-312.