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High-quality research is a top priority for BIDMC’s Harvard-affiliated Breast Imaging research program. Our academic group has created a formal research program to expand the scope and reach of the work. Program goals include focusing physicians in their short- and long-term research pursuits, expanding our research staff, and improving the visibility of our research group in local and larger communities through collaboration, social media, and committee participation.
Our primary work has evolved to focus on new technologies, value-based health care, and education. In 2019, we published six scientific papers and six educational reviews on these topics. We presented at multiple national conferences, including one scientific and six educational presentations at RSNA 2019, three scientific, and one educational presentation at ARRS 2019, one scientific presentation at the ACS Quality and Safety Conference, and one scientific presentation at the College of American Pathologists. At RSNA, our group was awarded Magna Cum Laude for two exhibits, one certificate of merit, and one was identified for Radiographics. At ARRS, our group received a Cum Laude Award, and a certificate of merit.
To promote visibility and collaboration within the BIDMC network, we partnered with members of Vascular and Interventional Radiology (VIR), breast pathology, breast surgery, and primary care on projects. We have engaged trainees at multiple levels from first-year through fellowship. We have also partnered with members outside our institution in areas of transgender health, mentorship, and breast imaging fellowship education.
Tejas Mehta, MD, MPH, FACR, Chief, Breast Imaging; Co-Director, Linsey BreastCare Center, and Assistant Professor of Radiology, has focused her research on new technology and value-based health care. To promote new technology, Dr. Mehta has begun an industry-funded, prospective trial evaluating Multi-Modal UltraSound Tomography (MUST), for breast cancer screening. She is also co-investigator on a trial evaluating Nonlinear Microscopy as an alternative to pathologic assessment for margin assessment. She supported the introduction of contrast-enhanced mammography (CEM) and Savi Scout Breast localizer to the institution. To promote value-based health care, Dr. Mehta is co-investigator on a study evaluating a risk assessment tool and has personally spearheaded multiple projects evaluating the timeliness of breast cancer diagnosis to surgery, the value of nurse navigation, and management of benign breast pathology. This year, Dr. Mehta was awarded fellowship in the Society of Breast Imaging and was invited to join the Value-Based Health Care Delivery Intensive Seminar at Harvard Business School.
Jordana Phillips, MD, Assistant Professor, Radiology, has focused her work primarily in the area of CEM. She has multiple industry-funded prospective trials studying CEM’s role for breast cancer screening, evaluating its diagnostic performance and the relative cost assessment of the exam compared with other common breast imaging exams. She was recently awarded a Prevent Cancer Foundation grant to study the role of CEM for women with a history of breast cancer. This project includes developing a national registry through the American College of Radiology (ACR) that will track outcomes for patients throughout the country. She was invited to participate in the ACR’s effort to develop a formal lexicon for CEM for the Breast Imaging and Reporting Database System (BI-RADS). She is spearheading multiple retrospective studies evaluating CEM’s performance in the clinical setting to better understand its value and to refine the technical protocol. In 2019, Dr. Phillips was awarded fellowship in the Society of Breast Imaging.
Rashmi Mehta, MD, MBA, Instructor, Radiology and Breast Imaging Fellowship Director, focuses her work primarily in breast imaging education. As the educational coordinator for all medical students, radiology residents, and fellows rotating through breast imaging, Dr. Mehta is formalizing expectations and curricula for each trainee group. Most recently, she published an article outlining recommended strategies for organizing a breast imaging fellowship and is designing a survey to send to all breast imaging fellowships nationwide to better understand current practice patterns. She is working on multiple educational projects with trainees that help teach about breast cancer staging and virtual curricula during COVID-19. Dr. Mehta was accepted to the AUR Faculty Development Program, which she will attend in 2021 due to this year’s COVID restrictions.
Our group also welcomed two new faculty members in 2020: Geunwon Kim, MD, PhD, and Linda Du, DO, MPH. Dr. Kim was awarded an RSNA Resident Research Grant to study MRI imaging of lymphedema and continues this work as a staff member. She was also awarded the Melissa Rosado de Christenson Award ARRS Resident award this year. Dr. Du is a graduate of the AUR’s Academic Leadership Development Program, with research interests in quality improvement, health care disparities, and trainee education.
*Perry H, Phillips J, Dialani V, Slanetz PJ, Fein-Zachary V, Karimova J, Mehta TS. Contrast-Enhanced Mammography: A Systematic Guide to Interpretation and Reporting. AJR Am J Roentgenol 2019 Jan; 212(1):222-31.
*Brown AL, Phillips J, Mehta TS, Brook A, Sharpe RE, Slanetz PJ, Dialani V. Breast MRI Ordering Practices in a Large Healthcare Network. Breast J. 2019 Feb 12.
Eismann J*, Heng YJ, Fleischmann-Rose K, Tobias AM, Phillips J, Wulf GM, Kansal KJ. Clin Breast Cancer. Interdisciplinary Management of Transgender Individuals at Risk for Breast Cancer: Case Reports and Review of the Literature. Clin Breast Cancer 2019 Feb; 19(1):e12-e19.
Phillips J, Fein-Zachary V, Slanetz PJ. Pearls and Pitfalls of Contrast-Enhanced Mammography. Journal of Society of Breast Imaging 2019. Mar; 1(2):64-72.
Dialani V, *Tseng I, Slanetz PJ, Phillips J, Fein-Zachary V, Karimova EJ, Brook A, Mehta TS. Potential Role of Abbreviated MRI for Breast Cancer Screening in an Academic Medical Center. Breast J 2019 Jul; 25(4):604-11.
Raj SD*, Phillips J, Mehta TS, Quintana LM, Fishman MD, Dialani V, Slanetz PJ. Management of BIRADS 3, 4A, 4B Lesions Diagnosed as Pure Papilloma by Ultrasound-guided Core Needle Biopsy: Is Surgical Excision Necessary? Acad Radiol 2019 Jul; 26(7):909-14
Shergill AK*, Camacho A, Horowitz JM, Jha P, Ascher S, Berchmans E, Slama J, Nougaret S, Wasnik AP, Robbins JB, Dighe MK, Wang CL, Nimhuircheartaigh JM, Phillips J, Menias C, Brook OR. Imaging of Transgender Patients: Expected Findings and Complications of Gender Reassignment Therapy. Uterine and Ovarian Cancer Disease Focused Panel of SAR. Abdom Radiol (NY) 2019 Aug; 44(8):2886-98. doi: 10.1007/s00261-019-02061-9.
Stowell JT*, Grimstad FW, Kirkpatrick DL, Brown ER, Santucci RA, Crane C, Patel AK, Phillips J, Ferreira MA, Ferreira FR, Ban AH, Baroni RH, Wu CC, Swan KA, Scott SA, Andresen KJ. Imaging Findings in Transgender Patients after Gender-affirming Surgery. Radiographics. 2019 Sep-Oct;39(5):1368-1392.
*Kim G, Phillips J, Cole E, Brook A, Mehta TS, Slanetz PJ, Fishman M, Karimova E, Mehta R, Lotfi L, Resteghini N, Raj S, Dialani VM. Comparison of Contrast-Enhanced Mammography with Conventional Digital Mammography in Breast Cancer Screening: A Pilot Study. J Am Coll Radiol JACR 2019 Oct; 16(10):1456-1463.
*Ghaderi KF, Phillips J, Perry H, Lotfi P, Mehta TS. Contrast-Enhanced Mammography: Current Applications and Future Direction. Radiographics 2019 Nov; 39 (7):1907-20.
Baker GM, Pyle ME, Tobias AM, Bartlett RA, Phillips J, Fein-Zachary VJ, Wulf GM, Heng YJ. Establishing a Cohort of Transgender Men and Gender Nonconforming Individuals to Understand the Molecular Impact of Testosterone on Breast Physiology. Transgend Health. 2019 Nov 19;4(1):326-330.
Mehta R, Lourenco A, Phillips J. A Roadmap for a Successful Breast Imaging Fellowship. Journal of Breast Imaging, Volume 2, Issue 2, March/April 2020, Pages 157–160.
Schonberg MA, Davis RB, Karamourtopoulos M, Pinheiro A, Sternberg S, Jacobson AR, Aliberti GM, Mehta TS, Cluett JL, Cohen M, Atlas T, Tung NM. A Pretest-posttest Trial of a Breast Cancer Risk Report for Women in their 40s. American Journal of Preventive Medicine. In Press.
Wei C*, Phillips J, Slanetz PJ, Lotfi P, Dialani V. Managing Architectural Distortion on Mammography Based on MR Enhancement. ARRS 2019. Certificate of Merit.
Karimi Z*, Phillips J, Lotfi P, Dialani V, Mehta R, Karimova J, Mehta TS. Background Parenchymal Enhancement on Contrast-Enhanced Mammography: Influence of Breast Tissue Density and Menstrual Cycle. ARRS 2019. Cum Laude Award.
Delaney E*, Dialani V, Phillips J, Mehta R, Slanetz PJ. Nipple/Areolar Complex: A Review of Common and Uncommon Pathology. ARRS 2019.
Wei CJ*, Phillips J, Slanetz PJ, Karimova EJ, Mehta TS, Fishman MDC, Dialani V. Impact of Using a Breast MRI Reporting Algorithm on Lesion Classification and Management. ARRS 2019.
Serres S*, Simon R, Mehta TS, Isaac A, Sarno D, Canacari E, Conklin J, Soto J, Harmon T, Kilroy C, Littlehale N, James T. Improving Access and Timeliness to Surgery for Patients with Breast Cancer: A Lean Approach to Problem-solving. 2019 American College of Surgeons Quality and Safety Conference 2019.
Guzman-Arocho YD*, Karimi Z*, Mehta TS, Phillips J, Baker G. Lobular Neoplasia Diagnosed on Core Needle Biopsy: A Twelve-Year, Single-Institution Review with Radiology-Pathology Correlation. College of American Pathologists (CAP) 2019.
Konstantopoulos CS*, Dialani VM, Mehta R, Mehta TS, Karimova EJ, Lotfi P, Fein-Zachary V, Brook A, Gill T, Phillips P. Contrast-Enhanced Mammography: Does Acquisition Time Matter? RSNA 2019.
Sun K*, Fein-Zachary V, Phillips J, Karimova EJ, Dialani V, Lotfi P, Mehta RJ, Mehta TS. Adding Value: An easy guide to be prepared for the FDA’s EQUIP Initiative and Beyond. RSNA 2019.
Gao Y*, Karimova EJ, Phillips J, Fein-Zachary VJ, Mehta TS, Mehta R, Dialani V, Lotfi P, Slanetz P. Breast Injectable – The Aunt Minnies and the Head-Scratchers. RSNA 2019. Certificate of Merit.
Karimova EJ, Baker G, Dialani VM, Fein-Zachary V, Mehta R, Mehta TS. Help Your Pathologist Help You: Successfully Arriving at a Diagnosis on Breast Biopsy. RSNA 2019.
Jiang BG*, Mehta R, Dialani VM, Karimova EJ, Fein-Zachary VJ, Lotfi P, Mehta TS, Phillips J. Collecting Pearls: An interactive review of breast cancer staging. RSNA 2019. Magna Cum Laude Award.
Sheth M, Phillips J, Catanzano T, McGuinness G. Optimizing the Mentor-Mentee Relationship: A Guide for Mentees. RSNA 2019.
Stowell J*, Kirkpatrick D, Grimstad F, Brown L, Zavaletta V, Robbins J, Baker G, Narayan A, Patel A, Phillips J, Wu C. Imaging Transgender Patients: A New Normal-Manifestations of Gender-Affirming Hormone Therapy. RSNA 2019. Certificate of Merit.
Stowell J*, Kirkpatrick D, Grimstad F, Brown L, Zavaletta V, Robbins J, Baker G, Narayan A, Patel A, Phillips J, Wu C. Imaging Transgender Patients: A New Normal-Cancers, Screening, and Imaging of Other Neoplastic Conditions. RSNA 2019. Identified for Radiographics
Guzmán-Arocho YD*, Yoshitake T, Cahill LC, Mehta TS, Houlihan MJ, Quintana LM, Fujimoto JG, Connolly JL. Visualization of Benign Breast Lesions by Nonlinear Microscopy. United States and Canadian Academy of Pathology (USCAP). 2020.
Guzmán-Arocho YD*, Yoshitake T, Cahill LC, Mehta TS, Houlihan MJ, Quintana LM, Fujimoto JG, Connolly JL. Nonlinear Microscopy: Evaluation of Invasive Breast Carcinoma. United States and Canadian Academy of Pathology (USCAP). 2020.
Vandeventer E*, Phillips J, Dialani V. DWI in Breast Imaging: A Practical Guide for Radiologists. ARRS 2020.
Gill T*, Phillips J, Dialani V. The Effect of Background Parenchymal Enhancement on Surgical Treatment and 5-Year Survival. ARRS 2020.
Mehta (PI). Transonic Imaging, Inc. A Prospective, Single-Center, Feasibility Study Assessing the Safety and Diagnostic Accuracy of the Multi-Modal UltraSound Tomography (MUST) Device in Identifying Malignant Breast Lesions as an Adjunct to Mammography.
Phillips J (PI). GE Healthcare. Comparison of Contrast-Enhanced Spectral Mammography and Breast MRI for Breast Cancer Screening.
Phillips J (PI). Prevent Cancer Foundation. Observational Study to Evaluate Outcomes of CEM for Women with a History of Breast Cancer.
Phillips J (PI). GE Healthcare. CEM for Women with a Personal History of Breast Cancer.
Mehta (Co-investigator). CRICO Risk Management Foundation. Mara Schoenberg (PI). Breast Cancer Risk Assessment Among Women 40-49 in Primary Care.