Stephen Juraschek, MD, PhD

Research Concentrations 

  • Hypertension & orthostatic hypotension
  • Diet & nutrition
  • Cardiovascular disease epidemiology & prevention trials

Contact Information

Email: sjurasch@bidmc.harvard.edu

Professional Biography

View Dr. Juraschek's CV (PDF)
View Dr. Juraschek's publication history at PubMed Author Search
View Dr. Juraschek's professional research networking profile at Harvard Catalyst

Dr. Juraschek is a clinician investigator with expertise in epidemiology and clinical trials. His primary area of interest is blood pressure regulation with standing and its relationship with adverse events such as falls and syncope. He is currently involved in several clinical trials examining a healthy eating pattern, the DASH diet, as well as sodium reduction in relation to cardiovascular risk factors, physical function, and blood pressure. He is also the principal investigator on a study that examining the effects of healthy diet on subclinical cardiovascular disease, in particular, high sensitivity troponin and NT-proB-type natriuretic peptide.

Dr. Juraschek has also published over 10 studies on uric acid and gout and is currently leading a clinical trial on diet for uric acid reduction. He is also interested in health disparities with regards to food access as well as participation in clinical trials. This interest has led to several recent studies on trial recruitment of under-represented groups.

Current Research Support

2017-2019
Rheumatology Research Foundation Innovative Research Award
This is a clinical trial of the DASH diet for uric acid reduction in patients with gout. We will also be examining effects of diet on cardiovascular risk factors.

NIH/NHLBI, K23HL135273, 2017-2022
Improved Characterization of Postural Blood Pressure Change in Older Adults
This study examines orthostatic hypotension measurements, its association with falls, and the impact of vitamin D on orthostatic hypotension. It will also examine the association between timing of orthostatic hypotension and position of the assessment with falls.

NIH/NHLBI, R21HL144876, 2018-2020
The Effects of the DASH Diet and Sodium Reduction on Subclinical Cardiac Damage
This study will determine the effects of the DASH diet, a healthful diet, as well as sodium intake, on subclinical cardiac injury and strain.

Selected Peer-Reviewed Publications

  1. Juraschek SP, Appel LJ, Miller ER III, Mukamal KJ, Lipsitz LA. Hypertension Treatment Effects on Orthostatic Hypotension and Its Relationship with Cardiovascular Disease. Hypertension. 2018 Aug 20. 0:HYPERTENSIONAHA.118.11337. PMID: 30354704.
  2. Juraschek SP, Daya N, Rawlings AM, Appel LJ, Miller ER 3rd, Windham BG, Griswold ME, Heiss G, Selvin E. Association of history of dizziness and long-term adverse outcomes with early vs later orthostatic hypotension assessment times in middle-aged adults. JAMA Intern Med 2017 Jul;177(9):1316-1323. PMID: 28738139.
  3. Juraschek SP, Miller ER 3rd, Weaver CM, Appel LJ. Effects of sodium reduction and the DASH diet in relation to baseline blood pressure. J Am Coll Cardiol 2017 Dec 12;70(23):2841-2848. PMID: 29141784.
  4. Juraschek SP, Gelber AC, Choi HK, Appel LJ, Miller ER 3rd. Effects of the dietary approaches to stop hypertension (DASH) diet and sodium intake on serum uric acid. Arthritis Rheumatol 2016 Nov;68:3002-3009. PMID: 27523583.
  5. Muntner P, Einhorn PT, Cushman WC, Whelton PK, Bello NA, Drawz PE, Green BB, Jones DW, Juraschek SP, Margolis KL, Miller ER 3rd, Navar AM, Ostchega Y, Rakotz MK, Rosner B, Schwartz JE, Shimbo D, Stergiou GS, Townsend RR, Williamson JD, Wright JT Jr, Appel LJ; 2017 National Heart, Lung, and Blood Institute Working Group. Blood Pressure Assessment in Adults in Clinical Practice and Clinic-Based Research: JACC Scientific Expert Panel. J Am Coll Cardiol. 2019 Jan 29;73(3):317-335. doi: 10.1016/j.jacc.2018.10.069. PMID: 30678763.
  6. Juraschek SP, Plante TB, Charleston J, Miller ER, Yeh HC, Appel LJ, Jerome GJ, Gayles D, Durkin N, White K, Dalcin A, Hermosilla M. Use of online recruitment strategies in a randomized trial of cancer survivors. Clin Trials. 2017 Dec 1:1740774517745829. doi: 10.1177/1740774517745829. [Epub ahead of print]. PMID: 29361843.