Metabolic Core Services and Pricing
Comprehensive Lab Animal Monitoring System (CLAMS)
The Columbus Instruments Comprehensive Lab Animal Monitoring System (CLAMS) is a system of 16 metabolic cages which allows for simultaneous measurement of numerous metabolic parameters including oxygen consumption (VO2), carbon dioxide production (VCO2), respiratory exchange ratio (RER), food consumption, locomotor activity levels, and (using implantable transmitters) core body temperature and heart rate.
View CLAMS availability
These instruments provide precise body composition measurements of fat, lean, free water, and total water masses in either tissue samples or live animals weighing up to 100 grams. Users can conduct the MRIs themselves (self-service) by signing up with the link below, or the Core will MRI all mice before any CLAMS experiment (full-service).
Sign up for self-serve MRI and complete the MRI Request Form.
FLIR Infrared Camera
The FLIR T420SC Thermal Imaging Camera and ResearchIR software enable users to measure heat lost due to thermal radiation, a potentially significant mechanism of weight loss and energy homeostasis.
Oxygen Bomb Calorimetry
A Parr 6725EA Semimicro Calorimeter and 1107 Oxygen Bomb allow measurement of the energy content of fecal waste from mice following different genetic or environmental stimuli, enabling crucial assessment of food metabolism efficiency in experimental mice.
The CLAMS data are analyzed using software developed by the Metabolic Core specifically for indirect calorimetry analysis. This software, called CalR, is web-based and available for free on calrapp.org. The data analysis service generates a complete package of time, bar and regression plots customized to your experiment.
||BIDMC or HDDC
|16 cage CLAMS usage/day
|FLIR training /hour