We owe much of what we understand about the etiology and treatment of renal diseases to the efforts of basic scientists bringing their findings from cell culture, micropuncture and animal models into the clinical realm. Your experience in this track will be defined by an immersion into this world, as an understanding of basic science techniques is required for translational research. This will be guided by one of our successful researchers as your mentor, bringing you into their labs and encouraging you to develop your own research focus. Their guidance will help you attain both early success (i.e. publication) while laying the groundwork for a rich career in research by helping you write grants and securing funding to support your own independent lab.
The future of kidney disease research lies in the exploration of the interface between our genetics and kidney diseases. The discovery of ApoL1 has changed the landscape of kidney disease, helping to explain the higher prevalence of CKD among those of African ancestry. Drs. Martin Pollak and David Friedman, the investigators who identified the ApoL1 high risk genotype and continue to study its biology, will help guide your work in the genetics of kidney diseases. As a member of the genetics track, your research will lead you to a greater understanding of how one might apply methods in gene sequencing and other specialized techniques in the laboratory setting. Fascinating work in genomics, proteomics and metabolomics is occurring throughout BIDMC and the Boston scientific community, and we can help facilitate collaborative projects with other mentors as well.
Mentors: Seth Alper, Eli Khankin, Martin Pollak, Robert Stanton, Martin Pollak, David Friedman