TAKE HOME MESSAGES:

  • The symptoms listed above are not unique to celiac disease and can occur with other disorders and diseases.
  • If you or your doctor recognize your symptoms in the list above (or in Level 2), consider getting tested for celiac disease.
  • If you suspect celiac disease, do not start a gluten-free diet on your own until you have consulted with a gastroenterologist and have been tested.
  • Early diagnosis and effective treatment of celiac disease greatly improves your health outcomes and reduces the risks of complications from untreated disease.

References:

  1. Green PH, Cellier C. Celiac Disease. N Eng J Med. 2007;357(17):1731-43.
  2. Aybar A. A Global Disease: The Iceberg Dilemma. In Real Life with Celiac Disease: Troubleshooting and Thriving Gluten-Free . Eds. Dennis M, Leffler D. AGA Press. Bethesda, MD, 2010.
  3. Beth Israel Deaconess Medical Center Celiac Center. Accessed August 11, 2011.
  4. Makharia GK, Verma AK, Armachand R et al. Prevalence of celiac disease in the northern part of India: a community-based study. J Gastroenterol Hepatol. 2011;26(5):894-900.
  5. Dalgic B, Sari S, Bastruk B et al. Prevalence of celiac disease in healthy Turkish school children. Am J Gastroenterol. 2011;106(8):1512-7.
  6. Israeli E, Hershcovic T, Grotto I et al. Prevalence of celiac disease in an adult Jewish population in Israel. Isr Med Assoc J. 2010;12(5):266-9.
  7. National Institutes of Health Publication No. 08-4269 September 2008. Accessed August 11, 2011.
  8. Kelly C. Common and Uncommon Presentations of Celiac Disease. In Real Life with Celiac Disease: Troubleshooting and Thriving Gluten-Free . Eds. Dennis M, Leffler D. AGA Press. Bethesda, MD, 2010.
  9. Cooper Bt, Holmes GK, Ferguson R et al. Gluten-sensitive diarrhea without evidence of celiac disease. Gastroenterology. 1981;81:192-194.
  10. Newnham ED. Does gluten cause gastrointestinal symptoms in subjects without coeliac disease? J Gastroenterol Hepatol. 2011;26:132-34.
  11. Leffler D. Gluten Intolerance: You Mean I Don't Have Celiac Disease? In Real Life with Celiac Disease: Troubleshooting and Thriving Gluten-Free . Eds. Dennis M, Leffler D. AGA Press. Bethesda, MD, 2010.
  12. Biesiekierski JR, Newnham ED, Irving PM et al. Gluten causes gastrointestinal symptoms in subjects without celiac disease: a double-blinded randomized placebo-controlled trial. Am J Gastroenterol. 2010; 106(3):508-14.
  13. Up to Date. Pathogenesis, epidemiology, and clinical manifestations of celiac disease in adults. Accessed October 9, 2011.
  14. University of Chicago Celiac Disease Center Impact Newsletters 2008; 8(1). Accessed August 11, 2011.

    Revision Date: 10-31-12
    Authors: Melinda Dennis, MS, RD, LDN and Annie Peer
    Editors: Suzanne Simpson, RD and Rupa Mukherjee, MD

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