Selected August Publications from BIDMC Faculty

Building on our culture of collaboration and innovation, our researchers are helping to transform medicine and health care delivery. Below are selected academic publications issued in the month of August.

Assessment of disparities in digital access among Medicare beneficiaries and implications for telemedicine
JAMA Internal Medicine / Research Letter / August 3, 2020
BIDMC Author: Ateev Mehrotra (Division of General Medicine)

Management options for an older adult with advanced chronic kidney disease and dementia
Annals of Internal Medicine / Beyond the Guidelines / August 4, 2020
BIDMC Authors: Risa Burns, Zahir Kanjee (Department of Medicine)

Trends in costs of care for Medicare beneficiaries treated in the emergency department from 2011 to 2016
JAMA Network Open / Research / August 6, 2020
BIDMC Authors: Laura Burke, Ryan Burke, Stephen Epstein (Department of Emergency Medicine)

Disparities in United States hospitalizations for serious infections in patients with and without opioid use disorder: A nationwide observational study
PLOS Medicine / Research / August 7, 2020
BIDMC Authors: Long Ngo, Shoshana Herzig (Division of General Medicine)

Approaches and challenges in SARS-CoV-2 vaccine development
Cell Host & Microbe / Perspective / August 10, 2020
BIDMC Authors: Gabriel Dagotto, Jingyou Yu, Dan Barouch (Center for Virology and Vaccine Research)

Cosmc controls B cell homing
Nature Communications / Research / August 10, 2020
BIDMC Authors: Junwei Zeng, Rajindra Aryal, Sylvain Lehoux, Kathrin Stavenhagen, Matthew Kudelka, Richard Cummings (Department of Surgery)

Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression
PNAS / Research / August 14, 2020
BIDMC Authors: Anna Fishbein, Haixia Yang, Victoria Hallisey, Jianjun Deng, Sanne Verheul, Allison Gartung, Dipak Panigrahy (Center for Vascular Biology Research, Department of Pathology, Cancer Center)

BRD4 prevents the accumulation of R-loops and protects against transcription–replication collision events and DNA damage
Nature Communications / Research / August 14, 2020
BIDMC Author: Michael Yaffe (Department of Surgery)

Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints
Nature Communications / Research / August 17, 2020
BIDMC Author: Michael Yaffe (Department of Surgery)

Effect of ascorbic acid, corticosteroids, and thiamine on organ injury in septic shock
JAMA / Research / August 18, 2020
BIDMC Authors: Michael Donnino, Ari Moskowitz, Lars Anderson, Long Ngo, Katherine Berg, Maureen Chase, Michael Cocchi (Department of Medicine)

Inducers of the endothelial cell barrier identified through chemogenomic screening in genome-edited hPSC-endothelial cells
PNAS / Research / August 18, 2020
BIDMC Author: Chad Cowan (Division of Cardiology)

International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium
npj Digital Medicine / Research / August 19, 2020
BIDMC Author: Gabriel Brat, Griffin Weber (Department of Surgery)

Racial and ethnic disparities in seasonal influenza vaccination among dialysis facilities in the United States
Journal of the American Society of Nephrology / Research / August 21, 2020
BIDMC Authors: John Danziger, David Friedman, Kenneth Mukamal (Department of Medicine)

Clostridioides difficile toxin A remodels membranes and mediates DNA entry into cells to activate toll like receptor 9 signaling
Gastroenterology / Research / August 22, 2020
BIDMC Authors: Xinhua Chen, Xiaotong Yang, Jun Huang, Dan Li, Hua Xu, Kelsey Shields, Joshua Hansen, Marianne Grant, Ciarán Kelly (Department of Medicine)

Revascularization practices and outcomes in patients with multivessel coronary artery disease who presented with acute myocardial infarction and cardiogenic shock in the US, 2009-2018
JAMA Internal Medicine / Research / August 24, 2020
BIDMC Authors: Robert Yeh, Eric Secemsky (Smith Center for Outcomes Research in Cardiology)

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy
Nature Cell Biology / Research / August 24, 2020
BIDMC Authors: Yang Gao, Naoe Taira Nihira, Jinfang Zhang, Yizeng Fan, Leina Ma, Jing Liu, Dong Wang, Xiaoming Dai, Hiroyuki Inuzuka, Brian North, Wenyi Wei (Department of Pathology)

Transite: A computational motif-based analysis platform that identifies RNA-binding proteins modulating changes in gene expression
Cell Reports / Resource / August 25, 2020
BIDMC Author: Michael Yaffe (Department of Surgery)

Community-level factors associated with racial and ethnic disparities in COVID-19 rates in Massachusetts
Health Affairs / Research / August 27, 2020
BIDMC Authors: Rishi Wadhera, Robert Yeh (Division of Cardiology)

Disruption of Cav1.2-mediated signaling is a pathway for ketamine-induced pathology
Nature Communications / Research / August 28, 2020
BIDMC Authors: Huan Chen, David Vandorpe, Xiang Xie, Seth Alper, Mark Zeidel, Weiqun Yu (Department of Medicine)