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Astaxanthin

En Español (Spanish Version)

Requirements/Sources | Therapeutic Dosages | Therapeutic Uses | Safety Issues | References

Requirements/Sources | Therapeutic Dosages | Therapeutic Uses | Safety Issues

Astaxanthin, a substance in the carotenoid family, provides the pink color of salmon and many other sea creatures. Like other carotenoids, astaxanthin is a strong antioxidant . It has been advocated for treating or preventing a number of health conditions, but as yet none of these proposed uses is supported by meaningful scientific evidence.

Requirements/Sources

Astaxanthin is not an essential nutrient. However, it is possible that increased intake of astaxanthin could provide health benefits.

Salmon is an excellent source of astaxanthin. A typical serving of Atlantic salmon provides approximately 1 mg of astaxanthin, while a similar serving of Pacific salmon might provide 4-5 mg. Krill oil is another good food source of astaxanthin.

When consistently exposed to high levels of ultraviolet light, the algae Haematococcus pluvialis produces very large quantities of astaxanthin, presumably to protect itself from injury. Haematococcus raised in this way is used as a commercial source of astaxanthin.

Therapeutic Dosages

In studies, astaxanthin has been given in doses ranging from 4-16 mg daily.

Some evidence suggests that astaxanthin is better absorbed when consumed in an oily base. 1

Therapeutic Uses

Many health claims for astaxanthin are based on the fact that it is a strong antioxidant. However, in recent years, scientific confidence in the medical benefits of antioxidants has waned; study after gigantic study of antioxidants such as vitamin E and beta-carotene have failed to find the hoped-for benefits.

Other proposed uses of astaxanthin have at least marginal supporting evidence from double-blind studies . In one such study, 30 men with infertility were given either placebo or 16 mg of astaxanthin daily, for a period three months. 2 The results showed possible small benefits on laboratory measures of fertility.

Another study tested astaxanthin combined with the carotenoid lutein as a possible supplement for enhancing recovery from exercise . In this small trial, 20 body-builders were given either placebo or the carotenoid combination for three weeks. 3 Participants then engaged in intense exercise. The results failed to show that use of the astaxanthin/lutein combination reduced muscle soreness or signs of muscle injury.

Weak evidence additionally hints that astaxanthin might reduce blood pressure , help prevent heart disease , lower cholesterol , protect the lens of the eye against cataracts , protect the stomach against ulcers , and reduce risk of macular degeneration . 4-6,8 However, for none of these uses (or any other) can astaxanthin yet be remotely called a proven treatment.

Two studies failed to find astaxanthin significantly more effective than placebo for treating stomach irritation in people with dyspepsia (nonspecific stomach pain). 9,10

Safety Issues

As a widely consumed nutritional substance, astaxanthin is expected to have a low order of toxicity. In human studies, no serious adverse effects have been seen. 2,3,7 Maximum safe doses in pregnant or nursing women, young children, or individuals with severe liver or kidney disease have not been determined.

 

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