Supplementation Likely Helpful
Individuals who take isoniazid may develop nerve problems such as tingling or numbness in the arms, hands, legs, and feet. The cause is believed to be the drug's interference with the action of vitamin B
In fact, use of isoniazid is one cause of the few occasions in which vitamin B
deficiency is seen in the developed world.
To prevent these complications, it may make sense to take vitamin B
supplements at a dose of 15 to 30 mg per day when using isoniazid.