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Molindone

Brand Name(s): | IMPORTANT WARNING | WHY is this medicine prescribed? | HOW should this medicine be used? | Are there OTHER USES for this medicine? | What SPECIAL DIETARY instructions should I follow? | What should I do IF I FORGET to take a dose? | What SIDE EFFECTS can this medicine cause? | What should I know about STORAGE and DISPOSAL of this medication? | What should I do in case of OVERDOSE? | What OTHER INFORMATION should I know? |

Brand Name(s):

  • Moban®

IMPORTANT WARNING

Molindone is no longer available in the United States after June 30, 2010. If you are currently taking molindone, you should call your doctor to discuss switching to another treatment.

Studies have shown that older adults with dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and that may cause changes in mood and personality) who take antipsychotics (medications for mental illness) such as molindone have an increased chance of death during treatment.

Molindone is not approved by the Food and Drug Administration (FDA) for the treatment of behavior problems in older adults with dementia. Talk to the doctor who prescribed this medication if you, a family member, or someone you care for has dementia and is taking molindone. For more information visit the FDA website: Web Site

WHY is this medicine prescribed?

Molindone is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions). Molindone is in a class of medications called conventional antipsychotics. It works by decreasing abnormal excitement in the brain.

HOW should this medicine be used?

Molindone comes as a tablet to take by mouth. It is usually taken three or four times a day. Try to take molindone at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take molindone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of molindone and gradually increase your dose after 3 to 4 days. Later, your doctor may increase or decrease your dose, depending on your response to the medication and the side effects you experience. Be sure to tell your doctor how you are feeling during your treatment with molindone.

Molindone may help to control your condition but will not cure it. Continue to take molindone even if you feel well. Do not stop taking molindone without talking to your doctor. It may take several weeks or longer for you to feel the full benefit of molindone.

Are there OTHER USES for this medicine?

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What SPECIAL PRECAUTIONS should I follow?

Before taking molindone,

  • tell your doctor and pharmacist if you are allergic to molindone or any other medications.
  • tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; barbiturates such as pentobarbital (Nembutal), phenobarbital (Luminal), and secobarbital (Seconal); medications for anxiety, mental illness, or seizures; narcotic medications for pain; phenytoin (Dilantin); sedatives; sleeping pills; tetracycline antibiotics such as demeclocycline (Declomycin), doxycycline (Doryx, Monodox, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), and tetracycline (Sumycin, Tetrex); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • tell your doctor if you have or have ever had depression or breast cancer. Also tell your doctor if you have ever had to stop taking a medication for mental illness due to severe side effects.
  • tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or if you plan to become pregnant or are breast-feeding. If you become pregnant while taking molindone, call your doctor. Molindone may cause problems in newborns following delivery if it is taken during the last months of pregnancy.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking molindone.
  • you should know that this medication may make you drowsy and may affect your thinking and movements. Do not drive a car or operate machinery until you know how this medication affects you.
  • ask your doctor about the safe use of alcohol while you are taking molindone. Alcohol can make the side effects of molindone worse.

What SPECIAL DIETARY instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What should I do IF I FORGET to take a dose?

Take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose, and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What SIDE EFFECTS can this medicine cause?

Molindone may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
  • drowsiness
  • dry mouth
  • blurred vision
  • increased saliva
  • nausea
  • constipation
  • difficulty urinating
  • blank facial expression
  • shuffling walk
  • unusual, slowed, or uncontrollable movements of any part of the body
  • restlessness
  • hyperactivity
  • depression
  • inappropriate happiness
  • breast enlargement
  • breast milk production
  • missed menstrual periods
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
  • fever
  • muscle stiffness
  • confusion
  • fast or irregular heartbeat
  • sweating
  • neck cramps
  • tongue that sticks out of the mouth
  • tightness in the throat
  • difficulty breathing or swallowing
  • fine, worm-like tongue movements
  • uncontrollable, rhythmic face, mouth, or jaw movements
  • seizures
  • erection that lasts for hours
  • vision loss, especially at night
  • seeing everything with a brown tint

Molindone may cause other side effects. Tell your doctor if you have any unusual problems while you are taking this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at Web Site ] or by phone [1-800-332-1088].

What should I know about STORAGE and DISPOSAL of this medication?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

What should I do in case of OVERDOSE?

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:
  • unusual, slowed, or uncontrollable movements of any part of the body
  • loss of consciousness

What OTHER INFORMATION should I know?

Keep all appointments with your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: May 16, 2011.

 

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