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Tetanus, Diphtheria, Pertussis (Tdap) Vaccine

Brand Name(s): | Other Name(s): | Why get vaccinated? | What is Tdap vaccine? | Who should not get Tdap vaccine or should wait? | What are the risks of a vaccine reaction? | What if there is a serious reaction? | The National Vaccine Injury Compensation Program | How can I learn more? |

Brand Name(s):

  • Adacel®(as a combination product containing Diphtheria, Tetanus Toxoids, Acellular Pertussis Vaccine)
  • Boostrix®(as a combination product containing Diphtheria, Tetanus Toxoids, Acellular Pertussis Vaccine)

Other Name(s):

  • Tdap

Why get vaccinated?

Tetanus, diphtheria and pertussis can be very serious diseases, even for adolescents and adults. Tdap vaccine can protect us from these diseases.

TETANUS(Lockjaw) causes painful muscle tightening and stiffness, usually all over the body. It can lead to tightening of muscles in the head and neck so you can't open your mouth, swallow, or sometimes even breathe. Tetanus kills about 1 out of 5 people who are infected.

DIPHTHERIAcan cause a thick coating to form in the back of the throat. It can lead to breathing problems, paralysis, heart failure, and death.

PERTUSSIS(Whooping Cough) causes severe coughing spells, which can cause difficulty breathing, vomiting and disturbed sleep. It can also lead to weight loss, incontinence, and rib fractures. Up to 2 in 100 adolescents and 5 in 100 adults with pertussis are hospitalized or have complications, which could include pneumonia or death.

These diseases are caused by bacteria. Diphtheria and pertussis are spread from person to person through coughing or sneezing. Tetanus enters the body through cuts, scratches, or wounds. Before vaccines, the United States saw as many as 200,000 cases a year of diphtheria and pertussis, and hundreds of cases of tetanus. Since vaccination began, tetanus and diphtheria have dropped by about 99% and pertussis by about 80%.

What is Tdap vaccine?

Tdap vaccine can protect adolescents and adults from tetanus, diphtheria, and pertussis. One dose of Tdap is routinely given at age 11 or 12. People who didnotget Tdap at that age should get it as soon as possible.

Tdap is especially important for health care professionals and anyone having close contact with a baby younger than 12 months.

Pregnant women should get a dose of Tdap duringeverypregnancy, to protect the newborn from pertussis. Infants are most at risk for severe, life-threatening complications from pertussis.

A similar vaccine, called Td, protects from tetanus and diphtheria, but not pertussis. A Td booster should be given every 10 years. Tdap may be given as one of these boosters if you have not already gotten a dose. Tdap may also be given after a severe cut or burn to prevent tetanus infection.

Your doctor can give you more information.

Tdap may safely be given at the same time as other vaccines.

Who should not get Tdap vaccine or should wait?

  • If you ever had a life-threatening allergic reaction after a dose of any tetanus, diphtheria, or pertussis containing vaccine, OR if you have a severe allergy to any part of this vaccine, you should not get Tdap. Tell your doctor if you have any severe allergies.
  • If you had a coma, or long or multiple seizures within 7 days after a childhood dose of DTP or DTaP, you should not get Tdap, unless a cause other than the vaccine was found. You can still get Td.
  • Talk to your doctor if you have epilepsy or another nervous system problem, had severe pain or swelling after any vaccine containing diphtheria, tetanus or pertussis, ever had Guillain-Barré Syndrome (GBS), or aren't feeling well on the day the shot is scheduled.

What are the risks of a vaccine reaction?

With any medicine, including vaccines, there is a chance of side effects. These are usually mild and go away on their own, but serious reactions are also possible.

Brief fainting spells can follow a vaccination, leading to injuries from falling. Sitting or lying down for about 15 minutes can help prevent these. Tell your doctor if you feel dizzy or light-headed, or have vision changes or ringing in the ears.

Mild Problems following Tdap:(Did not interfere with activities)

  • Pain where the shot was given (about 3 in 4 adolescents or 2 in 3 adults)
  • Redness or swelling where the shot was given (about 1 person in 5)
  • Mild fever of at least 100.4°F (up to about 1 in 25 adolescents or 1 in 100 adults)
  • Headache (about 3 or 4 people in 10)
  • Tiredness (about 1 person in 3 or 4)
  • Nausea, vomiting, diarrhea, stomach ache (up to 1 in 4 adolescents or 1 in 10 adults)
  • Chills, body aches, sore joints, rash, swollen glands (uncommon)

Moderate Problems following Tdap:(Interfered with activities, but did not require medical attention)

  • Pain where the shot was given (about 1 in 5 adolescents or 1 in 100 adults)
  • Redness or swelling where the shot was given (up to about 1 in 16 adolescents or 1 in 25 adults)
  • Fever over 102°F (about 1 in 100 adolescents or 1 in 250 adults)
  • Headache (about 3 in 20 adolescents or 1 in 10 adults)
  • Nausea, vomiting, diarrhea, stomach ache (up to 1 or 3 people in 100)
  • Swelling of the entire arm where the shot was given (up to about 3 in 100).

Severe Problems following Tdap:(Unable to perform usual activities; required medical attention)

  • Swelling, severe pain, bleeding and redness in the arm where the shot was given (rare).
  • Asevere allergic reactioncould occur after any vaccine (estimated less than 1 in a million doses).

What if there is a serious reaction?

What should I look for?
  • Look for anything that concerns you, such as signs of a severe allergic reaction, very high fever, or behavior changes.Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination.
What should I do?
  • If you think it is a severe allergic reaction or other emergency that can't wait, call 9-1-1 or get the person to the nearest hospital. Otherwise, call your doctor.
  • Afterward, the reaction should be reported to the Vaccine Adverse Event Reporting System (VAERS). Your doctor might file this report, or you can do it yourself through the VAERS web site at Web Site, or by calling1-800-822-7967.

VAERS is only for reporting reactions. They do not give medical advice.

The National Vaccine Injury Compensation Program

The National Vaccine Injury Compensation Program (VICP) is a federal program that was created to compensate people who may have been injured by certain vaccines.

Persons who believe they may have been injured by a vaccine can learn about the program and about filing a claim by calling1-800-338-2382or visiting the VICP website at Web Site.

How can I learn more?

  • Ask your doctor.
  • Call your local or state health department.
  • Contact the Centers for Disease Control and Prevention (CDC): Call1-800-232-4636or visit CDC's website at Web Site.

Tdap Vaccine Vaccine Information Statement. U.S. Department of Health and Human Services/Centers for Disease Control and Prevention National Immunization Program. 5/9/2013

AHFS® Consumer Medication Information. © Copyright, The American Society of Health-System Pharmacists, Inc., 7272 Wisconsin Avenue, Bethesda, Maryland. All Rights Reserved. Duplication for commercial use must be authorized by ASHP.

Selected Revisions: May 15, 2014.

 

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