| Risk Factors
Cocaine use disorder is when the use of cocaine harms a person’s health or social functioning, or when a person becomes dependent on cocaine. The powdered form of cocaine can be snorted or dissolved in water and injected. Crack is cocaine in a rock crystal form. It can be heated so its vapors can be smoked.
Cocaine use disorder is treatable. But, it takes hard work. Talk to your doctor if you think you have this condition.
Cocaine stimulates the brain to release large amounts of the hormone dopamine. Dopamine results in the euphoria commonly reported by cocaine abusers. As a person continues to use cocaine, a tolerance is developed. This means that higher doses and more frequent use are needed to maintain the euphoria.
Release of Dopamine in the Brain
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When a cocaine user stops using abruptly, a crash or withdrawal occurs. This results in an extremely strong craving for more cocaine. It also results in fatigue, loss of pleasure in life,
anxiety, irritability, suicidal thoughts, and sometimes paranoia. These withdrawal symptoms often prompt the user to seek more cocaine.
Cocaine use disorder is more common in young men and in those aged 18-25 years old. However, cocaine use disorder can occur in anyone at any age.
Symptoms associated with cocaine use disorder include:
Short-term effects include:
- Increase in energy
- Excessive talking
- Being mentally alert
- Decreased need for food and sleep
- Dilated pupils
- Increased temperature
- Increased heart rate
- Increased blood pressure
- Bizarre, erratic, or violent behavior
- Muscle twitches
Restlessness, irritability, and
- Heart attack
- Sudden death
Long-term effects include:
- Cravings that can't be controlled or predicted
- Increased tolerance
- Increased dosing
- Use of cocaine in a binge
- Increased irritability, restlessness, and paranoia
- Paranoid psychosis
- Hearing sounds that aren't there
Medical complications include:
- Heart rhythm abnormalities
- Heart attack
- Chest pain
- Respiratory failure
- Abdominal pain
- Chronic runny nose or septal perforation
Your doctor will ask about your symptoms and medical history. A physical exam will be done. The doctor will ask specific questions about your cocaine use, including how long you have been using the drug and how often.
Talk with your doctor about the best treatment plan for you. Treatment programs may be inpatient or outpatient and may:
- Require that you have already stopped using cocaine
- Involve a detoxification program
There are currently no medications to specifically treat cocaine use disorder.
Treatment with medication focuses on the symptoms of euphoria and craving. Medications that have shown some promise include:
- Modafinil—wakefulness promoting agent
- Topiramate—seizure medication
- Agonist replacement therapy
- Antidepressants—may be helpful for people in the early stages of stopping cocaine use
Behavioral therapies to help people quit using cocaine are often the only available, effective treatment for cocaine use disorder. Therapies include contingency management. With this program, people receive positive rewards for staying in treatment and remaining cocaine-free. Also,
cognitive behavioral therapy
helps people to learn how to abstain and remain abstinent from cocaine.
In rehab programs, people with cocaine use disorder stay in a controlled environment for 6-12 months. During this time, they may receive vocational rehab and other support to prepare them to return to society.
The best way to prevent cocaine use disorder is to never use cocaine. It is highly addictive and illegal.