These symptoms typically occur within 3-32 days of a tick bite.
Many infected people first notice a red rash, known as erythema migrans (EM). The rash starts as a small red spot at the site of the tick bite and expands over a period of days or weeks, forming a circular- or oval-shaped rash. The rash often resembles a bull’s eye: a red ring surrounding a clear or bluish area with a red center. The size of the rash can range from dime-sized to the entire width of a person’s back. More than one ring may develop. Typically, the rash goes away within four weeks.
Lyme Disease Rash
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Although Lyme disease is often associated with this rash, many people do not have the rash right away or at all. Or they may have a red rash, without the bull's eye pattern. If you have other symptoms that you think might be due to Lyme disease, see your doctor; do not wait for a rash to appear.
Muscle and joint aches, headache, fever (a temperature of 100-103 degrees Farenheit [37.7-39.4 degrees Celsius]), stiff neck, swollen glands, and fatigue may occur with or without the rash. These symptoms usually last about 5-21 days.