Risk Factors for Lymphedema
Posted 11/21/2011
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Lymphedema is a worry for all of us. The information that we are given is often scanty, and the facts seem few and sometimes contradictory. The incidence of lymphedema is quoted all over the place, and I know a surgeon who insists that none of his patients ever had had this problem. (Which I know is not true, as I know some of his patients who do have lymphedema). Here are a few facts:
1. Most women do not get lymphedema.
2. It can happen at any time--weeks or months or years after surgery.
3. With the smaller surgery of sentinel node dissection, the risk is smaller. Women who recieve radiation therapy to the axillary node area do have an increased risk.
4. It is treatable, but not curable.
Having given you the bullet points, here is an article about risk factors from Breast Cancer Research and Treatment:
Risk factors for lymphedema in breast cancer survivors, the Iowa Women's Health Study
Rehana L. Ahmed • Kathryn H. Schmitz •Anna E. Prizment • Aaron R. Folsom
Abstract
Risk factors for lymphedema and related arm symptoms in breast cancer (BC) survivors have not been examined using a large prospective population-based cohort. The Iowa Women's Health Study (IWHS) collected self-reported data for diagnosed lymphedema in 2004, and data for cancer diagnosis, treatment, behavioral and health characteristics between 1986 and 2003. We studied 1,287 women, aged 55-69 at baseline, who developed unilateral BC: n = 104 (8%) with diagnosed lymphedema, n = 475 (37%) with arm symptoms but without diagnosed lymphedema, and n = 708 without lymphedema. Age- and multivariate-adjusted logistic regression models examined risk factors for lymphedema and related arm symptoms (OR [95% confidence interval]). The mean time between BC and the 2004 survey was 8.1 ± 5.0 (mean ± SD) years. After multivariate adjustment, the following cancer characteristics were positively associated with lymphedema: tumor stage (regional vs. in situ: 3.92 [1.61-9.54]), number of excised nodes (highest vs. lowest quintile: 3.52 [1.32-9.34], P trend = 0.003), tumor-positive nodes (yes vs. no 2.12 [1.19, 3.79]), and adjuvant chemotherapy (yes vs. no: 3.05 [1.75-5.30]). Several health characteristics were positively associated with lymphedema: baseline body mass index (highest vs. lowest tertile: 3.24 [1.70-6.21]), waist and hip circumference, and general health (fair/poor vs. excellent: 3.44 [1.30-9.06]). Positive associations with arm symptoms were number of excised nodes (highest vs. lowest quintile: 2.38 [1.41-4.03], P trend = 0.007), axillary radiation (yes vs. no: 1.72 [1.15-2.57]), and baseline general health (fair/poor vs. excellent: 4.27 [2.60-7.00]). In the IWHS, obesity, poorer general health, and markers of more advanced cancer were risk factors for lymphedema and related arm symptoms in BC survivors.
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