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Inflammatory Breast Cancer

Posted 7/25/2010

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If you are reading this, you may well already know about inflammatory breast cancer, a rare variant of the disease. IBC does not present with a lump or thickening, but, rather, as a red or inflamed breast or a rash. A telltale sign is sometimes "peau d'orange" or skin that looks like the skin of an orange. Often, a doctor mistakes IBC for an infection and puts a woman on antibiotics. When this does not help, this diagnosis becomes more possible. IBC is an aggressive form of breast cancer, but there has been enormous progress in its treatment. I know many women with IBC who are doing fine. One particularly gratifying story is a woman who attends my support group for women with metastatic or Stage IV breast cancer. She was initially diagnosed with IBC nine (or maybe, ten) years ago. At that time, it had already spread to her bones, and she was put on weekly Taxol. She is still on weekly Taxol, and the cancer has not spread one single bit.

Here is a summary from the Komen Foundation:

Inflammatory Breast Cancer

FACTS FOR LIFE

For more information, call Susan G. Komen for the Cure® at 1-877 GO KOMEN (1-877-465-6636) or visit www.komen.org.

Symptoms of inflammatory

breast cancer

There are many symptoms of inflammatory breast

cancer. It is important to see your doctor if you have

any of these symptoms:

• one breast becomes much larger than the other one

(often sudden)

• warmth and swelling in the breast (often sudden)

• redness or pinkness that may look like an infection

• itching or pain in the breast that won't go away

• dimpling of the skin that may look like the skin of

an orange (called peau d' orange)

• ridges or thickened areas of skin

• nipple discharge

• nipple retraction or flattening

• change in the color of the areola (the dark skin

around the nipple)

• a bruise that does not go away

• swollen lymph nodes on the neck or under the arm

• a lump (although often there is no lump)

What is inflammatory breast cancer?

Inflammatory breast cancer (IBC) is rare and the most

aggressive form of breast cancer. It is called inflamma-

tory breast cancer because its main symptoms are

swelling and redness of the breast. Unlike other forms

of breast cancer, IBC often lacks a distinct lump or

tumor. Instead, cells grow in sheets that spread through

the breast. IBC is not usually found by mammograms

or ultrasounds unless there is a defined lump. If no

lump is present, it can be hard to diagnose. Because IBC

cells spread easily to other parts of the body, it requires

prompt diagnosis and treatment.

Who is at risk?

IBC accounts for about one to five percent of all breast

cancer cases in the United States.

• It is common in younger women. It has been seen in

women who are pregnant and in women who are

breastfeeding.

• It is slightly more common in African American

women than women of other races.

• Like other forms of breast cancer, it has also been

seen in men.

The symptoms of IBC are not always the same. It is

often misdiagnosed as a breast infection. Any of these

symptoms may be a sign of either IBC or a benign

breast infection (not cancer). If the symptoms last

longer than a week after starting antibiotics, insist

that your doctor do a biopsy to see if cancer cells

are present. If you do not feel that your doctor listens

to your concerns, get a second opinion.

Treatment for inflammatory

breast cancer

Treatment for inflammatory breast cancer often

starts with several rounds of chemotherapy, hormone

therapy or both. These systemic treatments affect the

whole body. They are used to kill or control any

cancer cells that might have spread to other parts of

the body. Then local treatments, such as radiation

therapy and surgery, are used to target the remaining

cancer cells in the breast and under the arm. Sometimes

systemic treatments are used again after the local

treatments. Systemic treatments used at follow-up

may include chemotherapy, hormone therapy and

targeted therapy.

If you have been diagnosed with inflammatory breast

cancer, know that there is hope. Advances in the

treatment of breast cancer have improved the 5-year

survival rates of women with IBC and new research is

ongoing. Staying positive is vital to your quality of life.

Ask your doctor about sources of help and support in

your area.

Resources

Organizations

Susan G. Komen for the Cure®

1-877 GO KOMEN (1-877-465-6636)

www.komen.org

American Cancer Society

1-800-ACS-2345

www.cancer.org

IBC Research Foundation

1-877-STOP-IBC

www.ibcresearch.org

Inflammatory Breast Cancer Clinic

1-877-MDA-6789

www.mdanderson.org

National Cancer Institute

1-800-4-CANCER

www.cancer.gov

Young Survival Coalition®

1-877-YSC-1011

www.youngsurvival.org

Internet

IBC Support

www.ibcsupport.org

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