Trial to study causes of delirium
BOSTON -- Delirium is an acute, confusional state that often affects older adults following surgery or serious illness. The condition develops in 14 to 56 percent of all hospitalized seniors, complicating hospital stays for over 2.5 million elderly individuals in the U.S. each year and taking a serious economic toll on the health-care system.
Now through a five-year $11 million Project Program grant from the National Institute on Aging, investigators at Beth Israel Deaconess Medical Center (BIDMC), Hebrew SeniorLife (HSL) and Brigham and Women's Hospital (BWH) will study the causes and outcomes of delirium.
Titled "Successful AGing after Elective Surgery [SAGES]" this major study will follow 500 surgery patients over age 70 with the goal of finding new approaches to prevent delirium and its long-term consequences for this growing population.
"We are eager and excited to undertake what we believe to be the first program project funded by the NIH [National Institutes of Health] to study delirium," says SAGES Overall Principal Investigator Sharon Inouye, MD, MPH, Director of the Aging Brain Center at Hebrew SeniorLife and Professor of Medicine at Harvard Medical School (HMS) and BIDMC.
"Delirium is a common complication of surgery but it's also potentially preventable. SAGES will help us to advance the understanding of the short-term and long-term outcomes of delirium, and ultimately, will help us improve care for older surgical patients."
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