beth israel deaconess medical center a harvard medical school teaching hospital

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Publications

  1. Lesperance LM, Gray ML, Burstein D. Determination of fixed charge density in cartilage using nuclear magnetic resonance. J Orthop Res 1992; 10:1-13.
  2. Burstein D, Gray ML, Hartman AL, Gipe R, Foy BD. Diffusion of small solutes in cartilage as measured by nuclear magnetic resonance (NMR) spectroscopy and imaging. J Orthop Res 1993; 11:465-478.
  3. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 1994; 32:66-76.
  4. Gray ML, Burstein D, Lesperance LM, Gehrke L. Magnetization transfer in cartilage and its constituent macromolecules. Magn Reson Med 1995; 34:319-325.
  5. Bashir A, Gray ML, Burstein D. Gd-DTPA2- as a measure of cartilage degradation. Magn Reson Med 1996; 36:665-673.
  6. Bashir A, Gray ML, Boutin R, Burstein D. In vivo imaging of GAG in articular cartilage using delayed Gd(DTPA)2- enhanced MRI. Radiology 1997; 205: 551-558.
  7. Allen RG, Burstein D, Gray ML. Monitoring Glycosaminoglycan Replenishment in Cartilage Explants with Gadolinium Enhanced MRI. J Orthop Res, 1999; 17: 430-436.
  8. Bashir A, Gray ML, Hartke J, Burstein D. Nondestructive Imaging of Human Cartilage Glycosaminoglycan Concentration by MRI. Magn Reson Med 1999; 41:857-865.
  9. Burstein D, Bashir A, Gray ML. MRI techniques in early stages of cartilage disease. Investigative Radiol. 2000; 35: 622-638.
  10. Burstein D, Velyvis JH, Scott KT, Stock KW, Kim YJ, Jaramillo D, Boutin RD, Gray ML. Protocol issues for delayed Gd(DTPA)2- enhanced MR imaging (dGEMRIC) for clinical evaluation of cartilage. Magn Reson Med 2001; 45:36-41.
  11. Recht M, Bobic V, Burstein D, Disler D, Gold G, Gray M, Kramer J, Lang P, McCauley T, Winalski C. Magnetic resonance imaging of articular cartilage. Clin Ortho Related Research 2001; 391S: S379-S396.
  12. Gray M, Burstein D, Xia Y. Biochemical (and functional) imaging of articular cartilage. Semin Musculoskelet Radiol. 2001; 5 (4): 329-44.
  13. Gillis A, Bashir A, McKeon B, Scheller A, Gray ML, Burstein D. Magnetic resonance imaging of relative glycosaminoglycan distribution in patients with autologous chondrocyte transplants. Investigative Radiol, 2001; 36: 743-748.
  14. Henkelman RM, Stanisz GJ, Menezes N, Burstein D. Can MTR be used to assess cartilage in the presence of Gd-DTPA2-? Magn Reson Med. 2002;48:1081-4
  15. Gillis A, Gray M, Burstein D. Relaxivity and diffusion of gadolinium agents in cartilage. Magn Reson Med. 2002;48:1068-71.
  16. Williams A, Oppenheimer RA, Gray ML, Burstein D. Differential recovery of GAG after IL-induced degradation of bovine articular cartilage depends on degree of degradation. Arthritis Research, 2003; 5:R97-105.
  17. Kim Y-J, Jaramillo D, Millis MB, Gray ML, Burstein D. Assessment of early osteoarthritis in hip dysplasia using delayed Gadolinium Enhanced MRI of Cartilage. J Bone Joint Surgery, 2003; 85-A: 1987-1992.
  18. Burstein D, Gray ML. New MRI techniques for imaging cartilage. J Bone Joint Surgery, 2003; 85-A:70-77.
  19. Burstein D, Gray ML. Potential of molecular imaging of cartilage. Sports Med Arthroscopy Review 2003; 11:182-191.
  20. Williams A, Gillis A, McKenzie C, Po B, Sharma L, Micheli L, McKeon B, Burstein D. Glycosaminoglycan distribution in cartilage as determined by delayed gadiolinium enhanced MRI of cartilage (dGEMRIC): Potential clinical applications. Amer J. Roentgenology, 2004; 182:167-172.
  21. Menezes N, Gray M, Harke J, Burstein D. T2 and T1rho MRI in Articular Cartilage Systems. Magn Reson Med, 2004; 51:503-509.
  22. Nieminen M, Menezes N, Williams A, Burstein D. T2 of Articular Cartilage in the Presence of Gd-DTPA2-. Magn Reson Med, 2004; 51:1147-1152.
  23. Samosky J, Burstein D, Grimson WE, Howe R, Martin S, Gray ML. Correlation of GAG distribution measured by dGEMRIC and spatially-localized mechanical stiffness in the human tibial plateau. J Orthop Res., in press.
  24. Burstein D, McKenzie C, Williams A. The potential for misinterpretation of combined T1/T2 weighted contrast enhanced MRI of cartilage. Radiology, in press.

S.M. Theses

  1. Hartman, A. Diffusion Coefficient of Protons in Compressed Cartilage, February 1991 (MIT, Mechanical Engineering).
  2. Bashir, A. Sodium NMR Relaxation Parameters in Cartilage: Implications for MR Imaging, February 1995 (MIT, Electrical Engineering and Computer Science).
  3. Allen, G.R. Mechanical Properties of Selectively Degraded Cartilage Explants: Correlation to the Spatiotemporal Distribution of Glycosaminoglycans, September 1996 (MIT, Mechanical Engineering).
  4. Williams, A. Regeneration of Cartilage Glycosaminoglycan After Degradation by Interleukin-1, January 2001 (MIT, Electrical Engineering and Computer Science).

M.Eng. Theses

  1. Liu, A. The Dependence of NMR Measured Diffusion, Magnetization Transfer, and T2 Relaxation on Fractional Water Content in Bovine Articular Cartilage, June 1995 (MIT, Electrical Engineering and Computer Science).
  2. Thomas, A. Two Compartment Model for Ion Distribution in Cartilage, December 1997 (MIT, Electrical Engineering and Computer Science).
  3. Po, B. Graphical Interface for Quantitative T1 and T2 Mapping of MRI Data. M.Eng. Thesis, Massachusetts Institute of Technology, 2001.

M.D. Theses

  1. Raman, C. Proton Diffusivity in Cartilage and Cartilage Macromolecules Using Nuclear Magnetic Resonance, June 1995 (Harvard-MIT Division of HST).

Doctoral Theses

  1. Lesperance, L.M. Ionic Properties of Cartilage: Determination by NMR Spectroscopy, July 1993 (MIT HST MEMP).
  2. Donahue, K.M. Studies of Gd-DTPA Relaxivity and Proton Exchange Rates in Tissue with Implications for MR Imaging of Regional Myocardial Perfusion, August 1993 (MIT HST MEMP)
  3. Bashir, A. Magnetic Resonance Imaging of Tissue Fixed Charge Density, June 1997 (MIT, Electrical Engineering and Computer Science).
  4. Samosky, J. Measuring, Modeling and Validating Articular Cartilage, June 2002 (MIT HST MEMP).
  5. Menezes N. Comparison of Relaxation Contrast Methods for Magnetic Resonance Imaging of Articular Cartilage Degradation, Sept 2002 (MIT HST MEMP)