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Publications

1. A. Nazarian , R. Müller. Time-lapsed microstructural imaging of bone failure behavior. Journal of Biomechanics, 37(1):55-65, 2004. [View PDF]

2. M.A. Kacena, R.A. Shivdasani, K. Wilson, Y. Xi, N. Troiano, A. Nazarian , C.M. Gundberg, M.L. Bouxsein, J.A. Lorenzo, M.C. Horowitz . Megakaryocyte-Osteoblast Interaction Revealed in Mice Deficient in Transcription Factors GATA-1 and NF-E2. Journal of Bone and Mineral Research, 19(4):652-60, 2004. [View PDF]

3. A. Nazarian , M. Stauber, R. Müller. Design and implementation of a novel mechanical testing system for cellular solids. Journal of Biomedical Materials Research-Part B: Biomaterials, 73B(2): 400-411, 2005. [View PDF]

4. O.B. Betz, V.M. Betz, A. Nazarian , C.G. Pilapil, M.S. Vrahas, M.L. Bouxsein, L.C. Gerstenfeld, T.A. Einhorn, C.H. Evans. Direct percutaneous gene delivery to enhance healing of segmental bone defects. Journal of Bone and Joint Surgery-American, 88:355-365, 2006. [View PDF]

5. A. Nazarian , M. Stauber, D. Zurakowski, B.D. Snyder, R. Müller. The interaction of microstructure and volume fraction in predicting failure in cancellous bone, Bone, 39:1196-1202, 2006. [View PDF]

6. L. Meinel, O.B. Betz, R.J. Fajardo, S. Hofmann, A. Nazarian , M. Hilbe, J. McCool, R. Langer, G. Vunjak-Novakovic, H.P. Merkle, B. Rechenberg, D.L. Kaplan, C. Kirker-Head. Silk based biomaterials to heal critical sized femur defects, Bone, 39(4):922-931, 2006.
[View PDF]

7. D.A. Chesler, G. Dai, J.L. Ackerman, M.I. Hrovat, M.J. Glimcher, B.D. Snyder, A. Nazarian , and Y. Wu. Water and fat suppressed proton projection MRI (WASPI) of rat femur bone, Magnetic Resonance in Medicine, 57(3):554-567, 2007. [View PDF]

8. A. Nazarian , J.A. Muller, D. Zurakowski, R. Müller, B.D. Snyder. Densitometric, morphometric and mechanical distributions in the human proximal femur, Journal of Biomechanics, 40(11):2473-2579, 2007. [View PDF]

9. C. Kirker-Head, V. Karageorgiou, S. Hofmann, R. Fajardo, O. Betz, H.P. Merkle, M. Hilbe, B. von Rechenberg, J. McCool, L. Abrahamsen, A. Nazarian , E. Cory, M. Curtis, D. Kaplan, L. Meinel. BMP-silk composite matrices heal critically sized femoral defects, Bone, 41(2): 247-255, 2007. [View PDF]

10. O. Betz, V. Betz, A. Nazarian , M. Egermann, L.C. Gerstenfeld, T.A. Einhorn, M.S. Vrahas, M.L. Bouxsein, C.H. Evans. Effect of the timing of adenoviral BMP-2 gene delivery on the healing of bone defects, Gene Therapy, 14(13):1039-1044, 2007. [View PDF]

11. A. Nazarian , D. Zurakowski, R. Müller and B.D. Snyder. Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone tissue density. Bone, 43: 302-311, 2008. PMID: 18539557; PMC Journal - In Process. [View PDF]

12. R.J. Fajardo, E. Cory, N.D. Patel, A. Nazarian , A. Laib, R.K. Manoharan, J.E. Schmitz, J.N. DeSilva, LM. MacLatchy, B.D. Snyder, M.L. Bouxsein. Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements. Bone, 44:176-184, 2009. [View PDF]

13. A. Nazarian , E. Cory, R. Müller, B. Snyder. Shortcomings of DXA in measuring differential changes in bone tissue density and structural morphology induced by metabolic bone diseases in cortical and cancellous bone in rat models, Osteoporosis International, 20(1):123-32, 2009. PMID: 18516487; PMC Journal - In Process. [View PDF]

14. A. Nazarian , B. Hermannsson, B.D. Snyder. Effects of tissue preservation on murine bone mechanical properties, Journal of Biomechanics, 42(1):82-6, 2009. PMID: 19081098; PMC Journal - In Process. [View PDF]

15. A. Nazarian , D. von Stechow, D. Zurakowski, R Müller and B.D. Bone volume fraction explains the variation in yield strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis, Calcified Tissue International, 84:368-379, 2008. [View PDF]

16. A. Nazarian , M. Bauernschmitt, C. Eberle, D. Meier, R. Müller, B.D. Snyder. Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging, Journal of Biomechanics, 41:3496-3501, 2008. PMID: 18990395; PMC Journal - In Process. [View PDF]

17. A. Nazarian , E. Cory, V. Entezari, V. Vartanians, R. Müller, B. Snyder. Compressive Axial Mechanical Properties of Rat Bone as Functions of Bone Volume Fraction, Apparent Density and Micro-CT Based Mineral Density for Virtual Bone Biomechanical Analysis, Journal of Biomechanics, 43(5): 953-960, 2009. PMID: 20003979; PMC Journal - In Process.
[View PDF]

18. A. Nazarian , V. Entezari, V. Vartanians, R. Müller, B.D. Snyder. An improved method to assess torsional properties of rodent long bones, Journal of Biomechanics, 42(11):1720-1725, 2009. PMID: 19447390; PMC Journal - In Process. [View PDF]

19. A. Nazarian , D. Meier, R. Müller, B.D. Snyder. The functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing, Journal of Orthopaedic Research, 27(12): 1667-1674, 2009. [View PDF]

20. D. Steines, S. Liew, C. Arnaud, R.V. Voracek, A. Nazarian , R. Müller, B.D. Snyder, P. Hess, P. Lang. Radiographic Trabecular 2D and 3D Parameters of Proximal Femoral Bone Cores Correlate with Each Other and with Yield Stress, Osteoporosis International, 20(11): 1929-1938, 2009. [View PDF]

21. B.D. Snyder, M.A. Cordio, A. Nazarian , S.D. Kwak, V. Entezari, D.J. Chang, D. Zurakowski, L.M. Parker. Noninvasive prediction of fracture risk in patients with metastatic cancer to the spine, Clinical Cancer Research, 15(24): 7676-7683, 2009.
[View PDF]

22. M.A. Pierre, D. Zurakowski, A. Nazarian , D.A. Hauser-Kara, B.D. Snyder. Assessment of the bilateral asymmetry of human femurs based on physical, densitometric, and structural rigidity characteristics, Journal of Biomechanics, 43(11): 2228-2236, 2010. [View PDF]

23. H. Cao, A. Nazarian , J.L. Ackerman, B.D. Snyder, M.I. Hrovat, G. Dai, M.J. Glimcher, Y. Wu. Quantitative 31P NMR spectroscopy and 1H MRI measurements of bone mineral and matrix density differentiate metabolic bones diseases in rat models, Bone, 46(6): 1582-1590, 2010. [View PDF]

24. T.J. McGlaston, V. Entezari, A. Nazarian , A. Ramappa. The safe zone for cross-pin fixation in anterior cruciate ligament reconstruction using antero-medial portal technique, Arthroscopy, 27(1):77-82, 2010. [View PDF]

25. A. Nazarian , L. Pezzella, A. Tseng, S. Baldassarri, O.B. Betz, V.M. Betz, C.H. Evans, B.D. Snyder. Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects, Calcified Tissue International, 86(5): 397-403, 2010. PMID: 20354683; PMC Journal - In Process. [View PDF]

26. V. Entezari, P.A. Basto, V. Vartanians, D. Zurakowski, B.D. Snyder, A. Nazarian . Non-invasive assessment of failure load in rat bones with simulated lytic lesions using computed tomography based structural rigidity analysis. Journal of Biomechanics, 44(3):552-556, 2011. PMID: 20926079; PMC Journal - In Process. [View PDF]

27. C.M. Gordon, L.B. Gordon, B.D. Snyder, A. Nazarian , N. Quinn, S. Huh, A. Giobie-Hurder, D. Neuberg, R. Cleveland, M. Kleinman, D.T. Miller, M. Kieran. Hutchinson-Gilford Progeria is a Skeletal Dysplasia. Journal of Bone and Mineral Research, 26(7):1670-1679, 2011. [View PDF]

28. C. Rosso, K. Kovtun, W. Dow, B. McKenzie, A. Nazarian , J.P. DeAngelis, A.J. Ramappa (in print).Comparison of All-Inside Meniscal Repair Devices with Matched Inside-Out Suture Repair. American Journal of Sports Medicine, 2011. [View PDF]

29. A. Nazarian, A. Araiza, C. Rosso, S. Aran, B.D. Snyder. Tensile properties of rat femoral bone as functions of bone volume fraction, apparent density and volumetric bone mineral density, Journal of Biomechanics, 44(13): 2482-2488, 2011. [View PDF]

30. V. Entezari, V. Vartanians, D. Zurakowski, N. Patel, R.J. Fajardo, R Müller, B.D. Snyder, A. Nazarian (accepted for publication). Further Improvements on the Factors Affecting Bone Mineral Density Measured by Quantitative Micro-Computed Tomography. Bone 2011. [View PDF]

31. M.D. Smith, S. Baldassarri, A. Tseng, V. Entezari, D. Zurakowski, B.D. Snyder, A. Nazarian (accepted for publication). Assessment of axial bone rigidity in rats with metabolic diseases using computed tomography based structural rigidity analysis, Bone and Joint Research, 2012. [View PDF]

32. L.B. Gordon, M.E. Kleinman, D.T. Miller, D. Neuberg, A. Giobbie-Hurder, M. Gerhard-Herman, L. Smoot, C.M. Gordon, R. Cleveland, B.D. Snyder, B. Fligor, W. R. Bishop, P. Statkevich, A. Regen, A. Sonis, S. Riley, C. Ploski, A. Corriea, N. Quinn, N.J. Ullrich, A. Nazarian, M.G. Liang, S.Y. Huh and M.W. Kieran. The Farnesyltransferase inhibitor lonafarnib improves disease in children with Hutchinson-Gilford Progeria syndrome, Proceedings of the National Academy of Sciences, USA, 2012. [View PDF]

33. R.H. Cleveland, L.B. Gordon, M.E. Kleinman, D.T. Miller, C.N. Gordon, B.D. Snyder, A. Nazarian, A. Giobbie-Hurder, D. Neuberg, M.W. Kieran. A Prospective Study of Radiographic Manifestations in Hutchinson-Gilford Progeria Syndrome, Am J Roentgenology, 2012. [View PDF]

34. V. Entezari, B.L. Trechsel, Jr., W.A. Dow, S.K. Stanton, C. Rosso, A. Müller, B. McKenzie, D. Li, V. Vartanians, J.P. DeAngelis, A.J. Ramappa and A. Nazarian. Design and manufacture of a novel system to simulate the real time biomechanics of basic and pitching shoulder motion using a cadaveric model, Bone and Joint Research, 2012. [View PDF]

35. A.M. Mueller, V Entezari, C. Rosso, B. McKenzie, A. Hasebroock, A. Cereatti, U. Della Croce, J.P. DeAngelis, A. Nazarian, A.J. Ramappa. The effect of simulated scapular winging on glenohumeral translations, Am J Sports Med, 2012. [View PDF]

36. A.C. Vale, M.F.C. Pereira, A. Mauricio, B. Vidal, A. Rodrigues, J.Caetano-Lopes, A. Nazarian, J.E. Fonseca, H. Canhao, M.F. Vaz. Micro-computed tomography assessment of human femoral trabecular bone for two disease groups (fragility fracture and coxarthrosis): Age and gender related effects, Journal of Biomedical Science and Engineering, 2013. [View PDF]

37. C. Ghobril, K. Chaoren, E.K. Rodriguez, A. Nazarian, M. Grinstaff (published online). A Dendritic Thioester Hydrogel Based on Thiol–Thioester Exchange as a Dissolvable Sealant System for Wound Closure. Angewandte Chemie, 52(52):14070-14074, 2013.
  [View PDF]

38. J.A. Rennick, A. Nazarian,V. Entezari, J. Kimbaris, A. Tseng, H. Nayeb-Hashemi, A. Vaziri, B.D. Snyder. Finite element analysis and computed tomography based structural rigidity analysis of rat tibia with simulated lytic defects, J Biomech, 46(15):2701-2709, 2013.
 [View PDF]

39. C. Rosso, A.M. Müller, V. Entezari, W.A. Dow, B. McKenzie, S.K. Stanton, D. Li, A. Cereatti, J.P. DeAngelis, A.J. Ramappa, A. Nazarian, U. Della Croce.  Preliminary evaluation of a robotic apparatus for the analysis of passive glenohumeral joint kinematics.  Journal of Orthopaedic Surgery and Research, 8(1):24, 2013.  PMCID: PMC3724692; http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724692/


40. J.P. DeAngelis, A. Chen, M. Wexler, B. Hertz, L. Grimladi-Bournissaint, A. Nazarian, A.J. Ramappa. Biomechanical characterization of unicortical button fixation: A novel technique for proximal subpectoral biceps tenodesis. Knee Surgery, Sports Traumatology, Knee surgery, Sports Traumatology, Arthroscopy, 2013. [View PDF]


41. A.N. Luu, S. Aran, F.J. Araiza Arroyo, V. Entezari, C. Rosso, B.DS. Snyder, A. Nazarian. Microstructural, material, densitometric, metabolic and mechanical variations in cortical and trabecular bones from normal, ovariectomized and vitamin D deficient rats. PLOS ONE, 8(12):e82709, 2013. [View PDF]


42. J. Caetano-Lopes, A. Rodrigues, A. Lopes, A.C. Vale, M.A.Pitts-Kiefer, B. Vidal, I.P. Perpetuo, J. Monteiro, Y.T. Konttinen, M.F. Vaz, A. Nazarian, H. Canhao, J.E. Fonseca. Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression, Clinical reviews of allergy and Immunology, 47(1): 38-45, 2014. [View PDF]


43. M. Stauber, A. Nazarian, R Muller. Limitations of average quantitative morphometry in predicting trabecular bone failure. Journal of Bone and Mineral Research, 29(1): 134-141, 2014. [View PDF]

44. N. Duggal, G. Paci, A. Narain, L. Grimaldi-Bournissaint, A. Nazarian. A computer assessment of the effect of hindfoot alignment on mechanical axis deviation. Computer Methods and Programs in Biomedicine, 113(1): 126-132, 2014. [View PDF]


45. A.J. Ramappa, A. Chen, B. Hertz, M. Wexler, L.Grimaldi Bournissaint, J.P. Denagelis, A. Nazarian.  A biomechanical evaluation of all inside two-stitch meniscal repair devices with matched inside-out suture repair. American Journal of Sports Medicine, 42(1): 194-199, 2014. [View PDF]


46. L.Anez-Bustillos, L.C. Derikx, N. Verdonschot, B.D. Snyder, A. Nazarian, E. Tanck. Finite element analysis and CT-based structural rigidity analysis to assess failure load in bones with simulated lytic defects.  Bone, 58C:160-167, 2014. PMID: 24145305; PMC Journal – In Process. [View PDF]


47. E.M. Fallon, A. Nazarian, D. Nehra, A.H. Pan, A. O’Loughlin, V. Nose, M. Puder. The effect of docosahexanenoic acid on bone microstructure in young mice, Journal of Surgical Research, 191(1):148-155, 2014. [View PDF]

48. A.M. Mueller, C. Rosso, V. Entezari, B. McKenzie, A. Hasebroock, U. Dellacroce, A. Nazarian, A.J. Ramappa, J.P. DeAngelis (accepted for publication). The effect of supraspinatus tears on glenohumeral translations in passive pitching motion. American Journal of Sports Medicine, 2014. [view PDF]

49. B.S. Beamer, K.C. Walley, E.R. Harlow, O.S. Manoukian, A. Masoudi, B. Hertz, C.Haeussler, J. Olson, J.P. DeAngelis, A.J. Ramappa, A. Nazarian (accepted for publication). A biomechanical evaluation of an all-inside radial meniscal tear repair device with matched inside-out suture repair, Arthroscopy, 2014.

50. A. Cereatti, C. Rosso, A. Nazarian, J.P. DeAngelis, A.J. Ramappa, U. Della Croce. Scapular motion tracking using an acromion skin marker-cluster: in vitro accuracy assessment. Journal of Medical and Biological Engineering, 35(1):, 2015.

51. A. Masoudi, B.S. Beamer, E.R. Harlow, O.S. Manoukian, K.C. Walley, B. Hertz, C. Haeussler, J. Olson, A. Nazarian, A.J. Ramappa, J.P. DeAngelis (accepted for publication). A biomechanical evaluation of all inside longitudinal meniscal tear repair devices with matched inside-out suture repair, Arthroscopy, 2014. 

52. C. Rosso, A.M. Mueller, B. McKenzie, V. Entezari, A. Cereatti, U. Della Croce, A. Nazarian, A.J. Ramappa, J.P. DeAngelis (accepted for publication). Bulk Effect of the Deltoid Muscle on the Glenohumeral Joint in a Full Torso Cadaveric Model of the Throwing Shoulder. Journal of Experimental Orthopaedics, 2014.

53. J. Yanamadala, V.K. Rathi, S. Maliye, H.A Win, A.L. Tran, M.K. Kozlov, G.M. Noetscher, A. Nazarian, S.N. Makarov (accepted for publication). Segmentation of the visible human project (VHP) female cryosection images within MATLAB environment, Procedia engineering, 2014.

54. A. Nazarian, V. Entezari, D. Zurakowski, J.N. Katz, M. Hochman, E.H. Baldini, S. Demehri, V. Vartanians, M.P. Rosen, M.C. Gebhardt, R.M. Terek, T.A. Damron, B.D. Snyder, Clinical Cancer Research (under review). Influence of CT-based Structural Rigidity Analysis on Fracture Prediction and Treatment Planning in Patients with Skeletal Metastasis: A Multi-center Survey Study, Journal of Bone and Joint Surgery, 2014.

55. T.A. Damron, A. Nazarian, V. Entezari, C. Brown, W. Grant, J.A. Hipp, N. Calderon, D. Zurakowski, R.M. Terek, M.E. Anderson, E.Y. Cheng, F. Cheung, A.J. Aboulafia, R. Turcotte P. Lin, , M.C. Gebhardt, B.D. Snyder (under review). CT-based structural rigidity analysis is more accurate than Mirels scoring system for fracture prediction in metastatic femoral lesions, Journal of Bone and Joint Surgery AM, 2014.

56. J.C. Villa-Camacho, R. Oftadeh, M. Perez-Viloria, A. Vaziri, A. Nazarian (under review). Biomechanics and mechanobiology of trabecular bone: A review, Journal of Biomechanical Engineering, 2014.

57. J.C. Villa-Camacho, O. Iyoha-Bello, S. Behrouzi, B.D. Snyder, A.Nazarian (Accepted for publication). Computed tomography based rigidity analysis: A review of the approach in preclinical and clinical studies, BoneKey, 2014.

58. S.M.A. Banijamali, R. Oftadeh, A. Nazarian, R. Goebel, A. Vaziri, H. Nayeb-Hashemi (under review). Effects of different loading patterns on the trabecular bone morphology of the proximal femur using adaptive bone remodeling, Journal of Biomechanical Engineering, 2014.

59. R. Oftadeh, V. Entezari, G. Spörri, J.C. Villa-Camacho, H. Krigbaum, E. strawich, L. graham, C. Rey, H.Chiu, R. Müller, A. Vaziri, A. Nazarian (under review). Hierarchical analysis and multi-scale modeling of rat cortical and trabecular bone, Journal of the Royal Society Interface, 2014.

60. J.C. Villa-Camacho, C. Ghobril, L. Anez-Bustillos, M.W. Grinstaff, E.K. Rodriguez, A. Nazarian (under review). Compared efficacy of lysine-based dendritic hydrogel with commercially available tissue sealants and adhesives, Journal of Investigative Surgery, 2014.

61. E.C. Pennington, B. Dionigi, F.L. Gray, A.Ahmed, J. Brazzo, A. Dolinko, N. Calderon, T. Darrah, D. Zurakowski, A. Nazarian, B.D. Snyder, D.O. Fauza (under review). Limb reconstruction with osseous grafts Derived from heterologous, decellularized, non-demineralized bone in a growing leporine model, Journal of the American College of Surgeons, 2014. 

62. J.P. DeAngelis, B. Hertz, M.T. Wexler, N. Patel, K.C. Walley, E.R. Harlow, O.S. Manoukian, A. Masoudi, A.J. Ramappa, A. Nazarian (under review). The effect of posterior plication on glenohumeral motion and subacromial contact pressure during abduction using in intact cadaver shoulder. Knee Surgery, Sports Traumatology, Arthroscopy, 2014. 

63. A. Nazarian, V. Entezari, J.A. Hipp, N. Calderon, D. Zurakowski, P. Lin, A.J. Aboulafia, R. Turcotte, M.E. Anderson, M.C. Gebhardt, E.Y. Cheng, R.M. Terek, T.A. Damron, B.D. Snyder (under review). CT-based rigidity analysis affects treatment planning of patients with skeletal metastasis, Journal of National Cancer Institute, 2014. 

64. E. Cowan, P. Nandivada, A. Nazarian, S.J. Carlson, M.I. Chang, A.H. Pan, M. Puder (under review). The effects of docosahexaenoic acid on bone microarchitecture and strength in a murine model. Pediatric Research, 2014.

65. A. Masoudi, J.P. DeAngelis, A.J. Ramappa, A. Nazarian (under review). Evolution of knowledge on meniscal biomechanics: A 40 year perspective, Journal of biomechanics, 2014.

Contact Information

Nazarian Lab
Center for Advanced Orthopaedic Studies
Beth Israel Deaconess Medical Center
330 Brookline Ave., RN 115
Boston, MA 02215
617-667-8512
anazaria@bidmc.harvard.edu