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Publications

1. A. Nazarian , R. Müller. Time-lapsed microstructural imaging of bone failure behavior. Journal of Biomechanics, 37(1):55-65, 2004. [View PDF]

2. M.A. Kacena, R.A. Shivdasani, K. Wilson, Y. Xi, N. Troiano, A. Nazarian , C.M. Gundberg, M.L. Bouxsein, J.A. Lorenzo, M.C. Horowitz . Megakaryocyte-Osteoblast Interaction Revealed in Mice Deficient in Transcription Factors GATA-1 and NF-E2. Journal of Bone and Mineral Research, 19(4):652-60, 2004. [View PDF]

3. A. Nazarian , M. Stauber, R. Müller. Design and implementation of a novel mechanical testing system for cellular solids. Journal of Biomedical Materials Research-Part B: Biomaterials, 73B(2): 400-411, 2005. [View PDF]

4. O.B. Betz, V.M. Betz, A. Nazarian , C.G. Pilapil, M.S. Vrahas, M.L. Bouxsein, L.C. Gerstenfeld, T.A. Einhorn, C.H. Evans. Direct percutaneous gene delivery to enhance healing of segmental bone defects. Journal of Bone and Joint Surgery-American, 88:355-365, 2006. [View PDF]

5. A. Nazarian , M. Stauber, D. Zurakowski, B.D. Snyder, R. Müller. The interaction of microstructure and volume fraction in predicting failure in cancellous bone, Bone, 39:1196-1202, 2006. [View PDF]

6. L. Meinel, O.B. Betz, R.J. Fajardo, S. Hofmann, A. Nazarian , M. Hilbe, J. McCool, R. Langer, G. Vunjak-Novakovic, H.P. Merkle, B. Rechenberg, D.L. Kaplan, C. Kirker-Head. Silk based biomaterials to heal critical sized femur defects, Bone, 39(4):922-931, 2006.
[View PDF]

7. D.A. Chesler, G. Dai, J.L. Ackerman, M.I. Hrovat, M.J. Glimcher, B.D. Snyder, A. Nazarian , and Y. Wu. Water and fat suppressed proton projection MRI (WASPI) of rat femur bone, Magnetic Resonance in Medicine, 57(3):554-567, 2007. [View PDF]

8. A. Nazarian , J.A. Muller, D. Zurakowski, R. Müller, B.D. Snyder. Densitometric, morphometric and mechanical distributions in the human proximal femur, Journal of Biomechanics, 40(11):2473-2579, 2007. [View PDF]

9. C. Kirker-Head, V. Karageorgiou, S. Hofmann, R. Fajardo, O. Betz, H.P. Merkle, M. Hilbe, B. von Rechenberg, J. McCool, L. Abrahamsen, A. Nazarian , E. Cory, M. Curtis, D. Kaplan, L. Meinel. BMP-silk composite matrices heal critically sized femoral defects, Bone, 41(2): 247-255, 2007. [View PDF]

10. O. Betz, V. Betz, A. Nazarian , M. Egermann, L.C. Gerstenfeld, T.A. Einhorn, M.S. Vrahas, M.L. Bouxsein, C.H. Evans. Effect of the timing of adenoviral BMP-2 gene delivery on the healing of bone defects, Gene Therapy, 14(13):1039-1044, 2007. [View PDF]

11. A. Nazarian , D. Zurakowski, R. Müller and B.D. Snyder. Quantitative micro-computed tomography: a non-invasive method to assess equivalent bone tissue density. Bone, 43: 302-311, 2008. PMID: 18539557; PMC Journal - In Process. [View PDF]

12. R.J. Fajardo, E. Cory, N.D. Patel, A. Nazarian , A. Laib, R.K. Manoharan, J.E. Schmitz, J.N. DeSilva, LM. MacLatchy, B.D. Snyder, M.L. Bouxsein. Specimen size and porosity can introduce error into microCT-based tissue mineral density measurements. Bone, 44:176-184, 2009. [View PDF]

13. A. Nazarian , E. Cory, R. Müller, B. Snyder. Shortcomings of DXA in measuring differential changes in bone tissue density and structural morphology induced by metabolic bone diseases in cortical and cancellous bone in rat models, Osteoporosis International, 20(1):123-32, 2009. PMID: 18516487; PMC Journal - In Process. [View PDF]

14. A. Nazarian , B. Hermannsson, B.D. Snyder. Effects of tissue preservation on murine bone mechanical properties, Journal of Biomechanics, 42(1):82-6, 2009. PMID: 19081098; PMC Journal - In Process. [View PDF]

15. A. Nazarian , D. von Stechow, D. Zurakowski, R Müller and B.D. Bone volume fraction explains the variation in yield strength and stiffness of cancellous bone affected by metastatic cancer and osteoporosis, Calcified Tissue International, 84:368-379, 2008. [View PDF]

16. A. Nazarian , M. Bauernschmitt, C. Eberle, D. Meier, R. Müller, B.D. Snyder. Design and validation of a testing system to assess torsional cancellous bone failure in conjunction with time-lapsed micro-computed tomographic imaging, Journal of Biomechanics, 41:3496-3501, 2008. PMID: 18990395; PMC Journal - In Process. [View PDF]

17. A. Nazarian , E. Cory, V. Entezari, V. Vartanians, R. Müller, B. Snyder. Compressive Axial Mechanical Properties of Rat Bone as Functions of Bone Volume Fraction, Apparent Density and Micro-CT Based Mineral Density for Virtual Bone Biomechanical Analysis, Journal of Biomechanics, 43(5): 953-960, 2009. PMID: 20003979; PMC Journal - In Process.
[View PDF]

18. A. Nazarian , V. Entezari, V. Vartanians, R. Müller, B.D. Snyder. An improved method to assess torsional properties of rodent long bones, Journal of Biomechanics, 42(11):1720-1725, 2009. PMID: 19447390; PMC Journal - In Process. [View PDF]

19. A. Nazarian , D. Meier, R. Müller, B.D. Snyder. The functional dependence of cancellous bone shear properties on trabecular microstructure evaluated using time-lapsed micro-computed tomographic imaging and torsion testing, Journal of Orthopaedic Research, 27(12): 1667-1674, 2009. [View PDF]

20. D. Steines, S. Liew, C. Arnaud, R.V. Voracek, A. Nazarian , R. Müller, B.D. Snyder, P. Hess, P. Lang. Radiographic Trabecular 2D and 3D Parameters of Proximal Femoral Bone Cores Correlate with Each Other and with Yield Stress, Osteoporosis International, 20(11): 1929-1938, 2009. [View PDF]

21. B.D. Snyder, M.A. Cordio, A. Nazarian , S.D. Kwak, V. Entezari, D.J. Chang, D. Zurakowski, L.M. Parker. Noninvasive prediction of fracture risk in patients with metastatic cancer to the spine, Clinical Cancer Research, 15(24): 7676-7683, 2009.
[View PDF]

22. M.A. Pierre, D. Zurakowski, A. Nazarian , D.A. Hauser-Kara, B.D. Snyder. Assessment of the bilateral asymmetry of human femurs based on physical, densitometric, and structural rigidity characteristics, Journal of Biomechanics, 43(11): 2228-2236, 2010. [View PDF]

23. H. Cao, A. Nazarian , J.L. Ackerman, B.D. Snyder, M.I. Hrovat, G. Dai, M.J. Glimcher, Y. Wu. Quantitative 31P NMR spectroscopy and 1H MRI measurements of bone mineral and matrix density differentiate metabolic bones diseases in rat models, Bone, 46(6): 1582-1590, 2010. [View PDF]

24. T.J. McGlaston, V. Entezari, A. Nazarian , A. Ramappa. The safe zone for cross-pin fixation in anterior cruciate ligament reconstruction using antero-medial portal technique, Arthroscopy, 27(1):77-82, 2010. [View PDF]

25. A. Nazarian , L. Pezzella, A. Tseng, S. Baldassarri, O.B. Betz, V.M. Betz, C.H. Evans, B.D. Snyder. Application of structural rigidity analysis to assess fidelity of healed fractures in rat femurs with critical defects, Calcified Tissue International, 86(5): 397-403, 2010. PMID: 20354683; PMC Journal - In Process. [View PDF]

26. V. Entezari, P.A. Basto, V. Vartanians, D. Zurakowski, B.D. Snyder, A. Nazarian . Non-invasive assessment of failure load in rat bones with simulated lytic lesions using computed tomography based structural rigidity analysis. Journal of Biomechanics, 44(3):552-556, 2011. PMID: 20926079; PMC Journal - In Process. [View PDF]

27. C.M. Gordon, L.B. Gordon, B.D. Snyder, A. Nazarian , N. Quinn, S. Huh, A. Giobie-Hurder, D. Neuberg, R. Cleveland, M. Kleinman, D.T. Miller, M. Kieran. Hutchinson-Gilford Progeria is a Skeletal Dysplasia. Journal of Bone and Mineral Research, 26(7):1670-1679, 2011. [View PDF]

28. C. Rosso, K. Kovtun, W. Dow, B. McKenzie, A. Nazarian , J.P. DeAngelis, A.J. Ramappa (in print).Comparison of All-Inside Meniscal Repair Devices with Matched Inside-Out Suture Repair. American Journal of Sports Medicine, 2011. [View PDF]

29. A. Nazarian, A. Araiza, C. Rosso, S. Aran, B.D. Snyder. Tensile properties of rat femoral bone as functions of bone volume fraction, apparent density and volumetric bone mineral density, Journal of Biomechanics, 44(13): 2482-2488, 2011. [View PDF]

30. V. Entezari, V. Vartanians, D. Zurakowski, N. Patel, R.J. Fajardo, R Müller, B.D. Snyder, A. Nazarian (accepted for publication). Further Improvements on the Factors Affecting Bone Mineral Density Measured by Quantitative Micro-Computed Tomography. Bone 2011. [View PDF]

31. M.D. Smith, S. Baldassarri, A. Tseng, V. Entezari, D. Zurakowski, B.D. Snyder, A. Nazarian (accepted for publication). Assessment of axial bone rigidity in rats with metabolic diseases using computed tomography based structural rigidity analysis, Bone and Joint Research, 2012. [View PDF]

32. L.B. Gordon, M.E. Kleinman, D.T. Miller, D. Neuberg, A. Giobbie-Hurder, M. Gerhard-Herman, L. Smoot, C.M. Gordon, R. Cleveland, B.D. Snyder, B. Fligor, W. R. Bishop, P. Statkevich, A. Regen, A. Sonis, S. Riley, C. Ploski, A. Corriea, N. Quinn, N.J. Ullrich, A. Nazarian, M.G. Liang, S.Y. Huh and M.W. Kieran. The Farnesyltransferase inhibitor lonafarnib improves disease in children with Hutchinson-Gilford Progeria syndrome, Proceedings of the National Academy of Sciences, USA, 2012. [View PDF]

33. R.H. Cleveland, L.B. Gordon, M.E. Kleinman, D.T. Miller, C.N. Gordon, B.D. Snyder, A. Nazarian, A. Giobbie-Hurder, D. Neuberg, M.W. Kieran. A Prospective Study of Radiographic Manifestations in Hutchinson-Gilford Progeria Syndrome, Am J Roentgenology, 2012. [View PDF]

34. V. Entezari, B.L. Trechsel, Jr., W.A. Dow, S.K. Stanton, C. Rosso, A. Müller, B. McKenzie, D. Li, V. Vartanians, J.P. DeAngelis, A.J. Ramappa and A. Nazarian. Design and manufacture of a novel system to simulate the real time biomechanics of basic and pitching shoulder motion using a cadaveric model, Bone and Joint Research, 2012. [View PDF]

35. A.M. Mueller, V Entezari, C. Rosso, B. McKenzie, A. Hasebroock, A. Cereatti, U. Della Croce, J.P. DeAngelis, A. Nazarian, A.J. Ramappa. The effect of simulated scapular winging on glenohumeral translations, Am J Sports Med, 2012. [View PDF]

36. A.C. Vale, M.F.C. Pereira, A. Mauricio, B. Vidal, A. Rodrigues, J.Caetano-Lopes, A. Nazarian, J.E. Fonseca, H. Canhao, M.F. Vaz. Micro-computed tomography assessment of human femoral trabecular bone for two disease groups (fragility fracture and coxarthrosis): Age and gender related effects, Journal of Biomedical Science and Engineering, 2013. [View PDF]

37. J. Caetano-Lopes, A. Rodrigues, A. Lopes, A.C. Vale, M.A.Pitts-Kiefer, B. Vidal, I.P. Perpetuo, J. Monteiro, Y.T. Konttinen, M.F. Vaz, A. Nazarian, H. Canhao, J.E. Fonseca. Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression, Clinical reviews of allergy and Immunology, 2013. [View PDF]

38. S. Fogerty, A. Nazarian, J.P. DeAngelis, A.J. Ramappa, V. Valderrabano, C. Rosso. Cyclic and load to failure testing of inside-out ethibond sutures in a meniscal model. Sport Orthopädie Traumatologie, 2013. [View PDF]

39. J.A. Rennick, A. Nazarian,V. Entezari, J. Kimbaris, A. Tseng, H. Nayeb-Hashemi, A. Vaziri, B.D. Snyder (accepted for publication). Finite element analysis and computed tomography based structural rigidity analysis of rat tibia with simulated lytic defects, J Biomech, 2013.

40. A.N. Luu, S. Aran, F.J. Araiza Arroyo, V. Entezari, C. Rosso, B.DS. Snyder, A. Nazarian (under review). Microstructural, material, densitometric, metabolic and mechanical variations in cortical and trabecular bones from normal, ovariectomized and vitamin D deficient rats, Journal of Osteoporosis, 2013.

41. A. Nazarian, V. Entezari, J.A. Hipp, N. Calderon, D. Zurakowski, P. Lin, A.J. Aboulafia, R. Turcotte, M.E. Anderson, M.C. Gebhardt, E.Y. Cheng, R.M. Terek, T.A. Damron, B.D. Snyder (under review). CT-based rigidity analysis affects treatment planning of patients with skeletal metastasis, J NCI, 2013.

42. C. Rosso, A.M. Müller, V. Entezari, W.A. Dow, S.K. Stanton, A. Cereatti, J.P. DeAngelis, A.J. Ramappa, A. Nazarian, U. Della Croce (under review). Evaluation of a robotic apparatus for the analysis of passive glenohumeral joint kinematics, Journal of Orthopaedic Surgery and Research, 2013.

43. C. Rosso, A.M. Mueller, B. McKenzie, V. Entezari, A. Cereatti, U. Della Croce, A. Nazarian, A.J. Ramappa, J.P. DeAngelis (under review). The role of the deltoid muscle in basic and pitching shoulder motions using a cadaveric model, Clinical Biomechanics, 2013.

44. L. Anez-Bustillos, L.C. Derikx, N. Verdonschot, B.D. Snyder, A. Nazarian, E. Tanck (under review). The application of finite-element analysis and ct-based structural rigidity analysis to assess failure load in bones with simulated lytic defects, Bone, 2013.

45. A.D. DiVasta, A. Nazarian, N. Calderon, N. Stokes, B.D. Snyder, C.M. Gordon (under review). Bone Structural Changes by Peripheral Quantitative Computed Tomography in Adolescents with Anorexia Nervosa: A Pilot Study, J Clin Dens, 2013.

46. M. Stauber, A. Nazarian, R Muller. Limitations of average quantitative morphometry in predicting trabecular bone failure (accepted for publication). Journal of Bone and Mineral Research, 2013.

47. E.M. Fallon, A. Nazarian, D. Nehra, A.H. Pan, A.A. O’Loughlin, V. Nose, M. Puder (under review). The Effect of Docosahexanenoic Acid on Bone Microstructure in Young Mice. Journal of Bone and Mineral Research, 2013.

Contact Information

Nazarian Lab
Center for Advanced Orthopaedic Studies
Beth Israel Deaconess Medical Center
330 Brookline Ave., RN 115
Boston, MA 02215
617-667-8512
anazaria@bidmc.harvard.edu