beth israel deaconess medical center a harvard medical school teaching hospital

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Stem Cell Research

The division has enhanced its existing collaboration with the Harvard Stem Cell Institute and Harvard University's Department of Stem Cell and Regenerative Biology.  Kevin Eggan, PhD, directs a laboratory that focuses on how developmental and environmental cues induce heritable variation in chromatin structure and how these variations regulate developmental potency, cell-fate and gene expression. In addition, Dr. Eggan's lab uses nuclear transfer and other approaches to develop human embryonic and induced pluripotent stem cell lines that carry the genes responsible for human neurodegenerative disease.  Dr Eggan's publication "Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons" in Science was cited by Time Magazine as the Top Medical Breakthrough of 2008.