Stem Cell Research
Stem Cell Research
The Reproductive Endocrinology division collaborates with the Harvard Stem Cell Institute and the Harvard University Department of Stem Cell and Regenerative Biology on stem cell research. Kevin Eggan, PhD directs a laboratory whose focus is how developmental and environmental cues induce heritable variation in chromatin structure and how these variations regulate developmental potency, cell-fate and gene expression. In addition, the Eggan lab uses nuclear transfer and other approaches to develop human embryonic and induced pluripotent stem cell lines that carry the genes responsible for human neurodegenerative disease. Dr Eggan’s publication “Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons”
(Science 2008; 321(5893):1218-21) was cited by Time Magazine as the Top Medical Breakthrough of 2008.
