2nd Annual Lupus Symposium
2nd Annual Symposium on
Systemic Lupus Erythematosus
September 19th, 2008
8:15 AM to 5:30 PM
The Pechet Room, Harvard Institutes of Medicine
77 Avenue Louis Pasteur, Boston, MA 02115
ATTENDANCE IS FREE / REGISTRATION IS REQUIRED
To register please e-mail your
• Name________________
• e-mail________________
• institution_____________
to Ms. Betty Chase: echase@bidmc.harvard.edu by August 31st, 2008
Morning Session:
8:30-9:00 AM Michael C. Carroll, PhD , Immune Disease Institute
"The lupus paradox: deficiency in early complement is a major factor for lupus"
9:00-9:30 AM Chack Yung Yu, D Phil, Columbus Children’s Research Institute
“Complement C4 in Human Systemic Lupus Erythematosus and Antiphospholipid Syndrome”
9:30-9:45 AM Daniel K. Brown, MD, PhD, Children’s Hospital
“A role for the SLAM family member, CD244, in a murine model of Systemic Lupus Erythematosus”
9:45-10:00 AM Jose C. Crispin, MD, Beth Israel Deaconess Medical Center
“Double Negative T cells in the Pathogenesis of Lupus Nephritis”
10:30-11:00 AM Susan A. Boackle, MD, University of Colorado
“Complement Receptor 2 as a Lupus Susceptibility Gene”
11:00-11:30 AM Robert W. Finberg, MD, University of Massachusetts Medical Center
“CR-1 and Pathogen Clearance”
11:30-11:45 AM Marton Keszei, Beth Israel Deaconess Medical Center
“Do one or more SLAM family genes contribute to murine lupus?”
11:45-12:00 PM Naotake Tsuboi, Ph.D., MD, Brigham and Women's Hospital
“Functional analysis of human neutrophil Fc gamma receptors in an experimental model of arthritis”
Afternoon Session:
1:30-2:00 PM Joseph Ahearn, MD, University of Pittsburgh
“Cell-Bound Complement Activation Products: Lupus Biomarkers and Clues to Pathogenesis”
2:00-2:30 PM Prof. Marina Botto, Imperial College London, England
“Complement, Atherosclerosis and Autoimmunity: lessons from animal models”
2:30-2:45 PM Guo-Min Deng, PhD, MD, Beth Israel Deaconess Medical Center
“The Role of Lipid Rafts in Pathogenesis of Systemic Lupus Erythematosus”
2:45-3:00 PM Wenda Gao, Ph.D. Beth Israel Deaconess Medical Center
“Distinctive role of B1 and B2 cells in T helper cell differentiation"
3:30-4:00 PM Wenchao Song, PhD, University of Pennsylvania
“Complement Regulatory Proteins and Systemic Autoimmune Disease”
4:00-4:30 PM Tanya Mayadas, PhD, Brigham and Women’s Hospital
“Role of human neutrophil Fc gamma receptors in antibody mediated inflammation: A study in transgenic mice”
4:30-4:45 PM Duane Wesemann, MD, PhD, Brigham and Women’s Hospital
“DNA end-joining-deficient mice as a tool for peripheral BCR editing and B cell tolerance”
4:45-5:00 PM Kei Yasuda, PhD, Boston University
“Hierarchical requirement for CpG motifs in dendritic cell activation induced by DNA-containing immune complexes”