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Recent Publications

 View complete list of 455 articles authored by Dr. Pandolfi

  1. A. Matsumoto, A. Pasut, M. Matsumoto, R. Yamashita, J. Fung, E. Monteleone, A. Saghatelian, K.I. Nakayama, J.G. Clohessy, P.P. Pandolfi. “mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide.” Nature. 2017, 541(7636):228-23.
  2. J. Guarnerio, M. Bezzi, J.C. Jeong, S.V. Paffenholz, K. Berry, M.M. Naldini, F. Lo-Coco, Y. Tay, A.H. Beck, P.P. Pandolfi. “Oncogenic Role of Fusion-circRNAs Derived from Cancer-Associated Chromosomal Translocations”. Cell. 2016, 165(2):289-302.
  3. F.A. Karreth, M. Reschke, A. Ruocco, C. Ng, B. Chapuy, V. Léopold, M. Sjoberg, T.M. Keane, A. Verma, U. Ala, Y. Tay, N. Seitzer, A. Bothmer, J. Fung, F. Langellotto, S.J. Rodig, O. Elemento, M.A. Shipp, D.J. Adams, R. Chiarle, P.P. Pandolfi. 2015. “The BRAF pseudogene functions as a competitive endogenous RNA and induces lymphoma in vivo.” Cell, 2015, 161(2):319-32.
  4. A. Papa, L. Wan, M. Bonora, L. Salmena, M.S. Song, R.M. Hobbs, A. Lunardi, K. Webster, C. Ng, R.H. Newton, N. Knoblauch, J. Guarnerio, K. Ito, L.A. Turka, A.H. Beck, P. Pinton, R.T. Bronson, W. Wei, P.P. Pandolfi. Cancer-associated PTEN mutants act in a dominant-negative manner to suppress PTEN protein function. Cell, 2014, 157(3): 595-610.
  5. S. J. Song, L. Poliseno, M.S. Song, U. Ala, L. Kats, G. Beringer, K. Webster, X. Yuan, J.E. Brock, A. L. Richardson, L. C. Cantley, P.P. Pandolfi.  MicroRNA-antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling. Cell, 2013, 154(2):311-24.
  6. I. Garcia-Cao, M.S. Song, R.M. Hobbs, G. Laurent, C. Giorgi, V.C.J. de Boer, D. Anastasiou, K. Ito, A. Sasaki, L. Rameh, A. Carracedo, M.G.Vander Heiden, L.C. Cantley, P. Pinton, M.C Haigis, P.P. Pandolfi. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Cell, 2012, 149(1):49-62.
  7. F.A. Karreth, Y. Tay, D. Perna, U. Ala, A.G. Rust, K.A. Webster, D. Weiss, P.A. Perez-Mancera, M. Krauthammer, R. Halaban, P. Provero, D.J. Adams, D.A. Tuveson and P.P. Pandolfi.  In vivo identification of tumor suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma. Cell, 2011, 147(2): 382-395.
  8. A.H. Berger, A.G. Knudson and P.P. Pandolfi. A continuum model for tumour suppression. Nature, 2011, 476(7359):163-9.
  9. Y. Tay, L. Kats, L. Salmena, D. Weiss, S.M. Tan, U. Ala, F. Karreth, L. Poliseno, P. Provero, F. Di Cunto, J. Lieberman, I. Rigoutsos and P.P. Pandolfi. Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell, 2011, 147 (2): 344-357. Highlighted on cover.
  10. L. Salmena, L. Poliseno, Y. Tay, L. Kats and P.P. Pandolfi. The ceRNA hypothesis: the new Rosetta stone of a hidden RNA language. Cell, 2011, 146(3): 353-8.
  11. M.S. Song, A. Carracedo, L. Salmena, S.J. Song, A. Egia, M. Malumbres and P.P. Pandolfi. Nuclear PTEN regulates the APC-CDH1 tumor suppressive complex in a phosphatase-independent manner. Cell, 2010, 144(2):187-99.
  12. C. Giorgi, K. Ito, H-K. Lin, C. Santangelo, M. R. Wieckowski, M. Lebiedzinska, A. Bononi, M. Bonora, J. Duszynski, R. Bernardi, R. Rizzuto, C. Tacchetti, P. Pinton, P. P. Pandolfi. PML Regulates Apoptosis at Endoplasmic Reticulum Modulating Calcium Release. Science, 2010, 330(6008): 1247-51.
  13. L. Poliseno, L. Salmena, J. Zhang, B. Carver, W. J. Haveman , P.P. Pandolfi. A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature 2010, 465:1033-8.
  14. R.M. Hobbs, M. Seandel, I. Falciatori, S. Rafii, P.P. Pandolfi. Plzf Regulates Germline Progenitor Self-Renewal by Opposing mTORC1. Cell. 2010, 142(3):468-79.

View complete list of 455 articles authored by Dr. Pandolfi

Contact Information

Pier Paolo Pandolfi, MD, PhD
Division of Genetics
Beth Israel Deaconess Medical Center
CLS Building, Room 401
330 Brookline Avenue
Boston, MA 02215

Lauren Southwood
Executive Assistant to Dr. Pier Paolo Pandolfi
P: 617-735-2145
F: 617-735-2120

Elizabeth Stack
Administrative Coordinator
Pandolfi Lab
P: 617-735-2860
F: 617-735-2120