beth israel deaconess medical center a harvard medical school teaching hospital

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Edward R. Marcantonio, MD, SM


Research Concentrations

  • Clinical Epidemiology
  • Delirium, Cognitive Function 
  • Outcomes of Hospitalization and Surgery in Older Adults 

Contact Information

Email: emarcant@bidmc.harvard.edu

Professional Biography

View Dr. Marcantonio's publication history at PubMed Author Search

View Dr. Marcantonio's professional research networking profile at Harvard Catalyst

Dr. Marcantonio is the Section Chief for Research in the Division of General Medicine and Primary Care at BIDMC, and Professor of Medicine at Harvard Medical School. Under Dr. Marcantonio’s leadership over the last 13 years, the program has grown from 8 to 18 investigators, while extramural funding has increased from $2 million to over $10 million annually. Dr. Marcantonio is an internationally recognized expert and clinical investigator in the area of delirium (acute confusion), in which he has performed numerous observational and interventional research studies. He currently leads two NIH-funded R01 studies in this area focused on improving diagnostic strategies for delirium, and biomarker discovery for delirium. Dr. Marcantonio's broader research interests include improving quality of care for hospitalized older adults, predictors of hospitalization and unplanned hospital readmission, and outcomes of non-cardiac and cardiac surgery in older adults.

Dr. Marcantonio serves as BIDMC site director of the HMS Fellowship in General Internal Medicine and Primary Care, teaches Epidemiology in the Clinical Effectiveness Program at Harvard School of Public Health, and has mentored nearly 50 students, postdoctoral fellows and junior faculty members. He has received the BIDMC Center for Faculty Development's Excellence in Mentoring Award, the HMS A. Clifford Barger Award for Excellence in Mentorship, and currently holds a Mid-Career Mentoring Award in Patient-Oriented Research from the National Institute on Aging. He also has been nationally recognized for his research, having received the Paul Beeson Physician Scholarship in Aging Research, the American Geriatrics Society Outstanding Scientific Achievement in Clinical Investigation Award, and is an elected member of the Association of American Physicians. 

Current Research Support (selected)

K24 AG035075   9/30/2010-5/31/2017 (NCE)
Mid-Career Mentoring Award for Patient-Oriented Research in Aging
Role: Principal Investigator

R01 AG044518 6/15/2014-2/28/2019
Development and Validation of a Delirium Severity Toolkit
Role: Site PI, Co-Investigator

R01AG051658 1/15/2016 - 12/31/2019
Advancing Understanding of Postoperative Delirium Mechanisms via Multi-Omics
Role: Principal Investigator

R01 AG030618 (Marcantonio/Fick) 4/15/2016 – 3/31/2020
READI: Researching Efficient Approaches to Delirium Identification
Role: Principal Investigator

Selected Peer-Reviewed Publications

  1. Mattison MLP, Catic A, Davis RB, Olveczky D, Moran J, Yang J, Aronson M, Zeidel M, Lipsitz LA, Marcantonio ER. A Standardized, Bundled Approach to Providing Geriatric-Focused Acute Care. J Am Geriatr Soc. 2014 May; 62(5):936-42. PMCID:PMC4382363.
  2. Marcantonio ER, Ngo L, O’Connor MA, Jones RN, Crane PK, Metzger ED, Inouye SK. 3D-CAM: Validation of a 3-Minute Diagnostic Interview for CAM-defined Delirium. Ann Int Med. 2014;161(8):554-61. PMCID:PMC4319978.
  3. Graham KL, Wilker EH, Howell MD, Davis RB, Marcantonio ER.  Differences between early and late readmissions among medical patients.  Ann Int Med. 2015;162(11):741-749.  PMCID: PMC4747330.
  4. Fick DM, Inouye SK, Guess J, Long LH, Jones RN, Saczynski JS, Marcantonio ER. Preliminary development of an ultra-brief 2-item bedside test for delirium. J Hosp Med. 2015 Oct;10(10):645-50.   PMCID: PMC4665114.3.
  5. Herzig SJ, Rothberg MB, Guess JR, Stevens JP, Marshall J, Gurwitz JP, Marcantonio ER.  Antipsychotic Use in Hospitalized Patients: Rates, Indications, and Predictors.  J Am Geriatr Soc. 2016. Feb;64(2):299-305. PMCID: PMC4762184.
  6. Cooper, Z, Rogers SO, Ngo LH, Guess J, Schmitt EM, Jones RN, Ayers DK, Walston JD, Gill TM, Inouye SK*, Marcantonio ER* (*co-last). A comparison of frailty measures as predictors of outcomes after orthopedic surgery. J Am Geriatr Soc. 2016;64(12):2464-71. PMCID: PMC5173406.