beth israel deaconess medical center a harvard medical school teaching hospital

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Shoshana J. Herzig, MD, MPH

Research Concentrations

• Pharmacoepidemiology
• Medication Utilization
• Physician Decision Making 

Contact Information


Professional Biography

View Dr. Herzig's  CV 

View Dr. Herzig's publication history at PubMed Author Search

View Dr. Herzig's professional research networking profile at Harvard Catalyst

Dr. Shoshana Herzig is Assistant Professor of Medicine at Harvard Medical School and a clinician investigator in the Division of General Medicine and Primary Care Sections of Hospital Medicine and Research at Beth Israel Deaconess Medical Center (BIDMC). She joined the faculty in 2010 after six highly successful years as a resident, chief resident, and fellow at BIDMC and Harvard Medical School. 

Her research interests are focused on patterns of medication utilization in the inpatient setting and associated outcomes, with the goal of informing physician decision-making in this realm. Her work thus far has focused on the risks and benefits of 2 commonly used classes of medications: acid-suppressive medications and sedating medications. Her work on acid-suppressive medication has provided an evidence base for decisions surrounding use of this class of medications in non-critically ill hospitalized patients. She received a Young Clinician Research Award from the Center for Integration of Medicine and Innovative Technology to develop a clinical decision support tool to reduce medication use fragmentation across transitions in care, focusing specifically on acid-suppressive medication. Her present work, funded by a K23 Award from the National Institute on Aging, aims to improve the care of hospitalized older adults through safer prescribing of sedating medications. In addition to extramural funding, Dr. Herzig has won several awards for her research, including the Mack Lipkin, Sr. Associate Member Award and the Geriatric Abstract Stipend Award, both  from the Society of General Internal Medicine. She additionally serves as the BIDMC site principal investigator for the Hospital Medicine Research and Reengineering Network (HOMERUN) – a nationwide research organization focused on measuring and improving the outcomes of hospitalized patients – and as Associate Editor for the Journal of Hospital Medicine.

In addition to her research activities, Dr. Herzig remains clinically active as an academic hospitalist at BIDMC. She has received numerous awards for her teaching of both BIDMC residents and Harvard Medical students on the general medicine wards.

Current Research Support

Young Clinician Research Award, Center for Integration of Medicine and Innovative Technology, 2010-2015
Reducing Medication Use Fragmentation Across Transitions. 
Role: PI

K23 AG042459, NIH/NIA, 2013-2018
Improving Use of Sedating Medications in Hospitalized Older Adults. 
Role: PI

Selected Peer-Reviewed Publications

1. Herzig SJ, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA 2009;301(20):2120-2128. 
2. Herzig SJ, Vaughn BP, Howell MD, Ngo LH, Marcantonio ER. Acid-suppressive medication use and the risk for nosocomial gastrointestinal tract bleeding. Arch Intern Med 2011;171(11):991-997. PMCID: PMC3142477.
3. Herzig SJ, Rothberg MB, Feinbloom DB, Howell MH, Ho KL, Ngo LH, Marcantonio ER. Risk factors for nosocomial gastrointestinal bleeding and use of acid-suppressive medication in non-critically ill patients. J Gen Intern Med 2013; May 28(5):683-690. doi: 10.1007/s11606-012-2296-x. PMCID: PMC3631055.
4. Rothberg MR, Herzig SJ, Pekow PS, Avrunin J, Lagu T, Lindenauer PK. Association between sedating medications and delirium in older inpatients. J Am Geriatr Soc 2013 Jun;61(6):923-930. doi: 10.1111/jgs.12253.
5. Herzig SJ, Rothberg MB, Cheung M, Ngo LH, Marcantonio ER. Opioid utilization and opioid-related adverse events in non-surgical patients in U.S. hospitals. J Hosp Med 2014 Feb;9(2):73-81. doi:1002/jhm.2012. Epub 2013 Nov 13. PMCID: PMC3976956
6. Bertisch SM, Herzig SJ, Winkelman JW, Buettner CB. National use of prescription medications for insomnia: NHANES 1999-2010. Sleep 2014 Feb 1;37(2):343-349. doi: 10.5665/sleep.3410. PMCID: PMC3900622.
7. Breu AC, Allen-Dicker J, Mueller S, Palamara K, Hinami K, Herzig SJ. Hospitalist and primary care physician perspectives on medication management of chronic conditions for hospitalized patients. J Hosp Med. 2014 May;9(5):303-9. doi: 10.1002/jhm.2137. Epub 2014 Feb 24. PMCID: PMC4017338
8. Herzig SJ, Doughty C, Lahoti S, Marchina S, Sana N, Feng W, Kumar S. Acid-Suppressive Medication Use in Acute Stroke and Risk of Hospital-Acquired Pneumonia. Ann Neurol. 2014 Aug 28. doi: 10.1002/ana.24262. [Epub ahead of print].
9. Herzig SJ, Guess JR, Feinbloom DB, Adra M, Afonso KA, Howell MD, Marcantonio ER. Improving Appropriateness of Acid-Suppressive Medication Use Via Computerized Clinical Decision Support. J Hosp Med.; in press.