• Research
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• Groopman Lab
• Hava Avraham Lab
• Shalom Avraham Lab
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• Ladias Lab

Publications

Hinton CV, Avraham S, Avraham HK. Contributions of Integrin-Linked Kinase to Breast Cancer Metastasis and Tumorigenesis. J Cell Mol Med. 2008 Mar 19.


Zagozdzon R, Fu Y, Avraham HK. Csk homologous kinase inhibits CXCL12-CXCR4 signaling in neuroblastoma. Int J Oncol. 2008 Mar;32(3):619-23.


Seng S, Avraham HK, Jiang S, Yang S, Sekine M, Kimelman N, Li H, Avraham S. The nuclear matrix protein, NRP/B, enhances Nrf2-mediated oxidative stress responses in breast cancer cells. Cancer Res. 2007 Sep 15;67(18):8596-604.


Jiang S, Fu Y, Williams J, Wood J, Pandarinathan L, Avraham S, Makriyannis A, Avraham S, Avraham HK. Expression and function of cannabinoid receptors CB1 and CB2 and their cognate cannabinoid ligands in murine embryonic stem cells. PLoS ONE. 2007 Jul 25;2(7):e641.


Tiburu EK, Bass CE, Struppe JO, Lorigan GA, Avraham S, Avraham HK. Structural divergence among cannabinoids influences membrane dynamics: a 2H solid-state NMR analysis. Biochim Biophys Acta. 2007 Sep;1768(9):2049-59.


Lee TH, Seng S, Sekine M, Hinton C, Fu Y, Avraham HK, Avraham S. Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR1/FLT1. PLoS Med. 2007 Jun;4(6):e186.


Jiang S, Seng S, Avraham HK, Fu Y, Avraham S. Process elongation of oligodendrocytes is promoted by the Kelch-related protein MRP2/KLHL1. J Biol Chem. 2007 Apr 20;282(16):12319-29. Epub 2007 Feb 25.


Fu Y, Zagozdzon R, Avraham R, Avraham HK. CHK negatively regulates Lyn kinase and suppresses pancreatic cancer cell invasion. Int J Oncol. 2006 Dec;29(6):1453-8.


Lee TH, Seng S, Li H, Kennel SJ, Avraham HK, Avraham S. Integrin regulation by vascular endothelial growth factor in human brain microvascular endothelial cells: role of alpha6beta1 integrin in angiogenesis. J Biol Chem. 2006 Dec 29;281(52):40450-60.


Seng S, Avraham HK, Jiang S, Venkatesh S, Avraham S. KLHL1/MRP2 mediates neurite outgrowth in a glycogen synthase kinase 3beta-dependent manner. Mol Cell Biol. 2006 Nov;26(22):8371-84. Epub 2006 Sep 18.


Tiburu EK, Karp ES, Birrane G, Struppe JO, Chu S, Lorigan GA, Avraham S, Avraham HK. 31P and 2H relaxation studies of helix VII and the cytoplasmic helix of the human cannabinoid receptors utilizing solid-state NMR techniques. Biochemistry. 2006 Jun 13;45(23):7356-65.


Kaminski R, Zagozdzon R, Fu Y, Mroz P, Fu W, Seng S, Avraham S, Avraham HK. Role of SRC kinases in Neu-induced tumorigenesis: challenging the paradigm using Csk homologous kinase transgenic mice. Cancer Res. 2006 Jun 1;66(11):5757-62.


Park I, Avraham HK. Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1. Exp Cell Res. 2006 Jul 1;312(11):1996-2008. Epub 2006 Apr 21.


Lee BC, Avraham S, Imamoto A, Avraham HK. Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice. Blood. 2006 Aug 1;108(3):904-7.


Jiang S, Avraham HK, Kim TA, Rogers RA, Avraham S. Receptor-type PTP-NP inhibition of Dynamin-1 GTPase activity is associated with neuronal depolarization. Cell Signal. 2006 Sep;18(9):1439-46.


Kim TA, Jiang S, Seng S, Cha K, Avraham HK, Avraham S. The BTB domain of the nuclear matrix protein NRP/B is required for neurite outgrowth. J Cell Sci. 2005 Dec 1;118(Pt 23):5537-48. Erratum in: J Cell Sci. 2006 Jan 1;119(Pt 1):195.


Zagozdzon R, Kaminski R, Fu Y, Fu W, Bougeret C, Avraham HK. Csk homologous kinase (CHK), unlike Csk, enhances MAPK activation via Ras-mediated signaling in a Src-independent manner. Cell Signal. 2006 Jun;18(6):871-81.


Lee BC, Lee TH, Zagozdzon R, Avraham S, Usheva A, Avraham HK. Carboxyl-terminal Src kinase homologous kinase negatively regulates the chemokine receptor CXCR4 through YY1 and impairs CXCR4/CXCL12 (SDF-1alpha)-mediated breast cancer cell migration. Cancer Res. 2005 Apr 1;65(7):2840-5.


Bu X, Avraham HK, Li X, Lim B, Jiang S, Fu Y, Pestell RG, Avraham S. Mayven induces c-Jun expression and cyclin D1 activation in breast cancer cells. Oncogene. 2005 Mar 31;24(14):2398-409.


Jiang S, Avraham HK, Park SY, Kim TA, Bu X, Seng S, Avraham S. Process elongation of oligodendrocytes is promoted by the Kelch-related actin-binding protein Mayven. J Neurochem. 2005 Mar;92(5):1191-203.


Zhang J, Zhu J, Bu X, Cushion M, Kinane TB, Avraham H, Koziel H. Cdc42 and RhoB activation are required for mannose receptor-mediated phagocytosis by human alveolar macrophages. Mol Biol Cell. 2005 Feb;16(2):824-34.


Avraham HK, Jiang S, Lee TH, Prakash O, Avraham S. HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells. J Immunol. 2004 Nov 15;173(10):6228-33.


Kim SO, Avraham S, Jiang S, Zagozdzon R, Fu Y, Avraham HK. Differential expression of Csk homologous kinase (CHK) in normal brain and brain tumors. Cancer. 2004 Sep 1;101(5):1018-27.


Melendez J, Turner C, Avraham H, Steinberg SF, Schaefer E, Sussman MA. Cardiomyocyte apoptosis triggered by RAFTK/pyk2 via Src kinase is antagonized by paxillin. J Biol Chem. 2004 Dec 17;279(51):53516-23.


Avraham H, Avraham S, Zagozdzon R. Use of antisense oligonucleotide technology to investigate signaling pathways in megakaryocytes. Methods Mol Biol. 2004;273:397-406.


Lee BC, Lee TH, Avraham S, Avraham HK. Involvement of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1alpha in breast cancer cell migration through human brain microvascular endothelial cells. Mol Cancer Res. 2004 Jun;2(6):327-38.


Price DJ, Avraham S, Jiang S, Fu Y, Avraham HK. Role of the aging vasculature and Erb B-2 signaling in epidermal growth factor-dependent intravasion of breast carcinoma cells. Cancer. 2004 Jul 1;101(1):198-205.


Liang XQ, Avraham HK, Jiang S, Avraham S. Genetic alterations of the NRP/B gene are associated with human brain tumors. Oncogene. 2004 Aug 5;23(35):5890-900.


Park SY, Avraham HK, Avraham S. RAFTK/Pyk2 activation is mediated by trans-acting autophosphorylation in a Src-independent manner. J Biol Chem. 2004 Aug 6;279(32):33315-22. Epub 2004 May 27.


Lee BC, Cha K, Avraham S, Avraham HK. Microarray analysis of differentially expressed genes associated with human ovarian cancer. Int J Oncol. 2004 Apr;24(4):847-51.