Publications
Balasubramanian A, Groopman JE, Ganju RK. Underlying pathophysiology of HCV infection in HIV-positive drug users. J Addict Dis. 2008;27(2):75-82.
Zhang X, Wang JF, Kunos G, Groopman JE. Cannabinoid modulation of Kaposi's sarcoma-associated herpesvirus infection and transformation. Cancer Res. 2007 Aug 1;67(15):7230-7.
Preet A, Ganju RK, Groopman JE. Delta9-Tetrahydrocannabinol inhibits epithelial growth factor-induced lung cancer cell migration in vitro as well as its growth and metastasis in vivo. Oncogene. 2008 Jan 10;27(3):339-46.
Park IW, Reddy MV, Reddy EP, Groopman JE. Evaluation of novel cell cycle inhibitors in mantle cell lymphoma. Oncogene. 2007 Aug 16;26(38):5635-42.
Balasubramanian A, Ganju RK, Groopman JE. Signal transducer and activator of transcription factor 1 mediates apoptosis induced by hepatitis C virus and HIV envelope proteins in hepatocytes. J Infect Dis. 2006 Sep 1;194(5):670-81.
Ghosh S, Preet A, Groopman JE, Ganju RK. Cannabinoid receptor CB2 modulates the CXCL12/CXCR4-mediated chemotaxis of T lymphocytes. Mol Immunol. 2006 Jul;43(14):2169-79.
Balasubramanian A, Munshi N, Koziel MJ, Hu Z, Liang TJ, Groopman JE, Ganju RK. Structural proteins of Hepatitis C virus induce interleukin 8 production and apoptosis in human endothelial cells. J Gen Virol. 2005 Dec;86(Pt 12):3291-301.
Balasubramanian A, Koziel M, Groopman JE, Ganju RK. Molecular mechanism of hepatic injury in coinfection with hepatitis C virus and HIV. Clin Infect Dis. 2005 Jul 1;41 Suppl 1:S32-7.
Zhang X, Wang JF, Chandran B, Persaud K, Pytowski B, Fingeroth J, Groopman JE. Kaposi's sarcoma-associated herpesvirus activation of vascular endothelial growth factor receptor 3 alters endothelial function and enhances infection. J Biol Chem. 2005 Jul 15;280(28):26216-24.
Groopman JE. A strategy for hope: a commentary on necessary collusion. J Clin Oncol. 2005 May 1;23(13):3151-2.
Zhang X, Groopman JE, Wang JF. Extracellular matrix regulates endothelial functions through interaction of VEGFR-3 and integrin alpha5beta1. J Cell Physiol. 2005 Jan;202(1):205-14.
Wang JF, Zhang X, Groopman JE. Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress. J Biol Chem. 2004 Jun 25;279(26):27088-97.
Munshi N, Balasubramanian A, Koziel M, Ganju RK, Groopman JE. Hepatitis C and human immunodeficiency virus envelope proteins cooperatively
induce hepatocytic apoptosis via an innocent bystander mechanism. J Infect Dis. 2003 Oct 15;188(8):1192-204.
Balasubramanian A, Ganju RK, Groopman JE. Hepatitis C virus and HIV envelope proteins collaboratively mediate interleukin-8 secretion through activation of p38 MAP kinase and SHP2 in hepatocytes. J Biol Chem. 2003 Sep 12;278(37):35755-66.
Choe EY, Schoenberger ES, Groopman JE, Park IW. HIV Nef inhibits T cell migration. J Biol Chem. 2002 Nov 29;277(48):46079-84
Wang JF, Zhang XF, Groopman JE. Stimulation of beta 1 integrin induces tyrosine phosphorylation of vascular endothelial growth factor receptor-3 and modulates cell migration. J Biol Chem. 2001 Nov 9;276(45):41950-7.
Park IW, Ullrich CK, Schoenberger E, Ganju RK, Groopman JE. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation.
J Immunol. 2001 Sep 1;167(5):2766-71.
Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE. Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine
phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells. Blood. 2001 Jun 1;97(11):3342-8.
Yang YM, Hatch WC, Liu ZY, Du B, Groopman JE. Beta-chemokine induction of activation protein-1 and cyclic AMP responsive element activation in human myeloid cells. Cell Growth Differ. 2001 Apr;12(4):211-21.
Wang JF, Park IW, Groopman JE. Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C. Blood. 2000 Apr 15;95(8):2505-13.
Park IW, Wang JF, Groopman JE. HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes. Blood. 2001 Jan 15;97(2):352-8.
Curt GA, Breitbart W, Cella D, Groopman JE, Horning SJ, Itri LM, Johnson DH, Miaskowski C, Scherr SL, Portenoy RK, Vogelzang NJ. Impact of cancer-related fatigue on the lives of patients: new findings from the Fatigue Coalition. Oncologist. 2000;5(5):353-60.
Ullrich CK, Groopman JE, Ganju RK. HIV-1 gp120- and gp160-induced apoptosis in cultured endothelial cells is mediated by caspases. Blood. 2000 Aug 15;96(4):1438-42.
Ganju RK, Brubaker SA, Chernock RD, Avraham S, Groopman JE. Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk. J Biol Chem. 2000 Jun 9;275(23):17263-8.
Venkatakrishnan G, Salgia R, Groopman JE. Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells. J Biol Chem. 2000 Mar 10;275(10):6868-75.
Munshi N, Groopman JE, Gill PS, Ganju RK. c-Src mediates mitogenic signals and associates with cytoskeletal proteins upon vascular endothelial growth factor stimulation in Kaposi's sarcoma cells. J Immunol. 2000 Feb 1;164(3):1169-74.
Park IW, Wang JF, Groopman JE. Expression and utilization of co-receptors in HIV and simian immunodeficiency virus infection of megakaryocytes. AIDS. 1999 Oct 22;13(15):2023-32.
Munshi N, Ganju RK, Avraham S, Mesri EA, Groopman JE. Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor activation of c-jun amino-terminal kinase/stress-activated protein kinase and lyn kinase is mediated by related adhesion focal tyrosine kinase/proline-rich tyrosine kinase 2. J Biol Chem. 1999 Nov 5;274(45):31863-7.
Groopman JE, Itri LM. Chemotherapy-induced anemia in adults: incidence and treatment. J Natl Cancer Inst. 1999 Oct 6;91(19):1616-34. Review. Erratum in: J Natl Cancer Inst 2000 Mar 15;92(6):497.
Park IW, Koziel H, Hatch W, Li X, Du B, Groopman JE. CD4 receptor-dependent entry of human immunodeficiency virus type-1 env-pseudotypes into CCR5-, CCR3-, and CXCR4-expressing human alveolar macrophages is preferentially mediated by the CCR5 coreceptor. Am J Respir Cell Mol Biol. 1999 May;20(5):864-71.
Dutt P, Wang JF, Groopman JE. Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis. J Immunol. 1998 Oct 1;161(7):3652-8.
Ganju RK, Brubaker SA, Meyer J, Dutt P, Yang Y, Qin S, Newman W, Groopman JE. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem. 1998 Sep 4;273(36):23169-75.
Wang JF, Liu ZY, Groopman JE. The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood. 1998 Aug 1;92(3):756-64.
Hatch WC, Ganju RK, Hiregowdara D, Avraham S, Groopman JE. The related adhesion focal tyrosine kinase (RAFTK) is tyrosine phosphorylated and participates in colony-stimulating factor-1/macrophage colony-stimulating factor signaling in monocyte-macrophages. Blood. 1998 May 15;91(10):3967-73.
Ganju RK, Munshi N, Nair BC, Liu ZY, Gill P, Groopman JE. Human immunodeficiency virus tat modulates the Flk-1/KDR receptor, mitogen-activated protein kinases, and components of focal adhesion in Kaposi's sarcoma cells. J Virol. 1998 Jul;72(7):6131-7.
Groopman JE. Fatigue in cancer and HIV/AIDS. Oncology (Williston Park). 1998 Mar;12(3):335-44; discussion 345-6, 351. Review.
Ganju RK, Dutt P, Wu L, Newman W, Avraham H, Avraham S, Groopman JE. Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK.
Blood. 1998 Feb 1;91(3):791-7.
Sloand EM, Groopman JE. Transfusion in HIV disease. Curr Opin Hematol. 1997 Nov;4(6):449-54. Review.
Wang JF, Ganju RK, Liu ZY, Avraham H, Avraham S, Groopman JE. Signal transduction in human hematopoietic cells by vascular endothelial growth
factor related protein, a novel ligand for the FLT4 receptor. Blood. 1997 Nov 1;90(9):3507-15.
Liu ZY, Ganju RK, Wang JF, Schweitzer K, Weksler B, Avraham S, Groopman JE. Characterization of signal transduction pathways in human bone marrow endothelial cells. Blood. 1997 Sep 15;90(6):2253-9.
Groopman JE. Impact of transfusion on viral load in human immunodeficiency virus infection.
Semin Hematol. 1997 Jul;34(3 Suppl 2):27-33.
Vogelzang NJ, Breitbart W, Cella D, Curt GA, Groopman JE, Horning SJ, Itri LM, Johnson DH, Scherr SL, Portenoy RK. Patient, caregiver, and oncologist perceptions of cancer-related fatigue: results of a tripart assessment survey. The Fatigue Coalition. Semin Hematol. 1997 Jul;34(3 Suppl 2):4-12.
Hatch WC, Freedman AR, Boldt-Houle DM, Groopman JE, Terwilliger EF. Differential effects of interleukin-13 on cytomegalovirus and human
immunodeficiency virus infection in human alveolar macrophages. Blood. 1997 May 1;89(9):3443-50.
