Usheva Lab: Research
Our Major Research Interests
- The mechanism and regulation of transcription initiation
- Electronic features of the basic transcription complex.
Our laboratory is focused on transcription initiation and the regulation of initiation in cells. Gene expression dynamics are governed by a multitude of factors, including promoter DNA regulatory interactions, posttranslational modifications of transcription factors and mRNA stability. We want to assemble a coherent picture of gene transcription initiation and all its mechanisms of control.
Current Research
There are a number of current research projects we are interested in:
- TFIIB Autoacetylation Mechanism
- Thermal Dynamics of DNA Opening
- Markers for Transplantation Rejection
- Protein-protein and Protein-DNA Interactions Measured by Capacitance
