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Complete list of Dr. Mantzoros' publications >>


Selected Publications


Moon HS, Liu X, Nagel JM, Chamberland JP, Diakopoulos KN, Brinkoetter MT, Hatziapostolou M, Wu Y, Robson SC, Iliopoulos D, Mantzoros CS. Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut. 2012 Jun 26.; 62(4):561-70.

Dalamaga M, Diakopoulos KN, Mantzoros CS. The role of adiponectin in cancer: a review of current evidence. Endocr Rev. 2012 Aug;33(4):547-94. Epub 2012 Apr 30.

Rejeski WJ, Ip EH, Bertoni AG, Bray GA, Evans G, Gregg EW, Zhang Q; Look AHEAD Research Group. Lifestyle change and mobility in obese adults with type 2 diabetes. N Engl J Med. 2012 Mar 29;366(13):1209-17.

Lee DH, Huang H, Choi K, Mantzoros C, Kim YB. Selective PPARγ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice. Am J Physiol Endocrinol Metab. 2012 Mar;302(5):E552-60. doi: 10.​1152/​ajpendo.​00569.​2011. Epub 2012 Jan 3.

Kang ES, Magkos F, Kim BS, Zhai R, Su L, Kim YS, Christiani DC, Lee HC, Mantzoros CS. Variants of the adiponectin and adiponectin receptor-1 genes and posttransplantation diabetes mellitus in renal allograft recipients.J Clin Endocrinol Metab. 2012 Jan;97(1):E129-35. Epub 2011 Nov 2.


Moon HS, Chamberland JP, Aronis K, Tseleni-Balafouta S, Mantzoros CS. Direct role of adiponectin and adiponectin receptors in endometrial cancer: in vitro and ex vivo studies in humans. Mol Cancer Ther. 2011 Dec; 10(12):2234-43. Epub 2011 Oct 6.

Moragianni VA, Aronis KN, Chamberland JP, Mantzoros CS. Short-term energy deprivation alters activin and follistatin but not inhibin B levels of lean healthy women in a leptin-independent manner.J Clin Endocrinol Metab. 2011 Dec; 96(12):3750-8. Epub 2011 Sep 14.

Brinkoetter M, Magkos F, Vamvini M, Mantzoros CS. Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women. Am J Physiol Endocrinol Metab. 2011 Jul; 301(1):E99-E104. Epub 2011 Apr 19.

Moon HS, Matarese G, Brennan AM, Chamberland JP, Liu X, Fiorenza CG, Mylvaganam GH, Abanni L, Carbone F, Williams CJ, De Paoli AM, Schneider BE, Mantzoros CS. Efficacy of metreleptin in obese patients with type 2 diabetes: cellular and molecular pathways underlying leptin tolerance. Diabetes.2011 Jun;60(6):1647-56.

Chou SH, Chamberland JP, Liu X, Matarese G, Gao C, Stefanakis R, Brinkoetter MT, Gong H, Arampatzi K, Mantzoros CS. Leptin is an effective treatment for hypothalamic amenorrhea. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6585-6590. Epub 2011 Apr 4.

Stuebe AM, Mantzoros C, Kleinman K, Gillman MW, Rifas-Shiman S, Gunderson EP, Rich-Edwards J. Duration of lactation and maternal adipokines at three years postpartum. Diabetes. 2011 Apr;60(4):1277-85. Epub 2011 Feb 24.

Choi KM, Yannakoulia M, Park MS, Cho GJ, Kim JH, Lee SH, Hwang TG, Yang SJ, Kim TN, Yoo HJ, Baik SH, Kim SM, Mantzoros CS. Serum adipocyte-fatty acid binding protein, retinol binding protein 4, and adiponectin levels in relation to the development of metabolic syndrome in Korean boys: A 3-year long prospective cohort study. Am J Clin Nutr. 2011 Jan;93(1):19-26. Epub 2010 Nov 24.


Moon HS, Chamberland J, Diakopoulos K, Fiorenza C, Ziemke F, Schneider B, Mantzoros C. Leptin and amylin act in an additive manner to activate overlapping signaling pathways in peripheral tissues; in vitro and ex vivo studies in humans. Diabetes Care. 2010 Jan;34(1):132-8. Epub 2010 Sep 24.

Kotsopoulos J, Tworoger SS, Campos H, Chung FL, Clevenger CV, Franke AA, Mantzoros CS, Ricchiuti V, Willett WC, Hankinson SE, Eliassen AH. Reproducibility of plasma and urine biomarkers among premenopausal and postmenopausal women from the Nurses' Health Studies. Cancer Epidemiol Biomarkers Prev. 2010 Apr;19(4):938-46. Epub 2010 Mar 23. 

Scheer FAJL, Chan JL, Fargnoli J, Chamberland J, Arampatzi K, Shea SA, Blackburn GL, Mantzoros CS. Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions.Diabetologia. 2010 Nov;53(11):2401-5. Epub 2010 Aug 12.

Friberg E, Orsini N, Mantzoros CS, Wolk A. Alcohol intake and endometrial cancer risk: a meta-analysis of prospective studies.Br J Cancer. 2010 Jun 29;103(1):127-31.

Taveras EM, Rifas-Shiman SL, Rich-Edwards JW, Gunderson EP, Stuebe AM, Mantzoros CS. Association of Maternal Short Sleep Duration With Adiposity and Cardiometabolic Status at 3 Years Postpartum.Obesity (Silver Spring). 2010 May 20. [Epub ahead of print]

Sun Q, Cornelis MC, Kraft P, Qi L, van Dam RM, Girman CJ, Laurie CC, Mirel DB, Gong H, Sheu CC, Christiani DC, Hunter DJ,  Hu FB, Mantzoros CS. Genome-wide association study identifies polymorphisms in LEPR as determinants of plasma soluble leptin receptor levels. Hum Mol Genet. 2010 May 1;19(9):1846-55.

Ruschke K, Fishbein L, Dietrich A, Klöting N, Tönjes A, Oberbach A, Fasshauer M, Jenkner J, Schön MR, Stumvoll M, Blüher M, Mantzoros CS. Gene expression of PPAR{gamma} and PGC-1{alpha} in human omental and subcutaneous adipose tissues is related to insulin resistance markers and mediates beneficial effects of physical training.Eur J Endocrinol. 2010 Mar;162(3):515-23. Epub 2009 Dec 4.


Brennan AM, Sweeney LL, Liu X, Mantzoros CS. Walnut consumption increases satiation but has no effect on insulin resistance or the metabolic profile over a 4 day period. Obesity 2010 Jun; 18(6):1176-82.

Fung TT, Rexrode KM, Mantzoros CS, Manson JE, Willett WC, Hu FB. Mediterranean diet and incidence and mortality of coronary heat disease and stroke in women. Circulation 2009 Feb 17; 119: 1067-8.

Scheer F, Hilton M, Mantzoros CS, Shea S. Adverse metabolic and cardiovascular consequences of circadian misalignment. PNAS. 2009; 106 (11) 4453-8.

Ligibel JA, Giobbie-Hurder A, Olenczuk A, Campbell N, Salinardi N, Winer EP, Mantzoros CS. Impact of a Mixed Strength and Endurance Exercise Intervention on Levels of Adiponectin, High Molecular Weight Adiponectin and Leptin in Breast Cancer Survivors. Cancer Causes and Control 2009 Oct;20(8):1523-8.

Brennan AM, Lee JH, Tsiodras S, Chan JL, Doweiko J, Chimienti SN, Wadhwa SG, Karchmer AW, Mantzoros CS . r-metHuLeptin improves highly active antiretroviral therapy-induced lipoatrophy and the metabolic syndrome, but not through altering circulating IGF and IGF-binding protein levels: observational and interventional studies in humans. Eur J Endo 2009; 160(2):173-6.

Contact Information

Division Of Endocrinology, Diabetes, and Metabolism
Beth Israel Deaconess Medical Center
Stoneman 820
330 Brookline Ave
Boston, MA 02215