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Kahn Lab

Our Major Research Interests

  • Molecular mechanisms of insulin resistance.
  • Molecular pathogenesis of type 2 diabetes.
  • Pathogenesis of obesity.
  • Insulin action, glucose transport, leptin action, metabolism.
  • The adipocyte as an endocrine organ.

Recent Work

  • Discovered new signaling pathway involved in leptin action - AMP activated protein kinase.
  • Discovered importance of the Glut4 glucose transporter in adipocytes in whole body insulin action.
  • Investigating the role of protein tyrosine phosphatase 1B and other phosphatases in insulin action and body weight regulation.
  • Discovered that PTP1B regulates leptin signaling by dephosphorylating Jak 2.

For a complete listing of Dr. Kahn's publications, click here

Contact Information

Kahn Lab
Division Of Endocrinology, Diabetes, and Metabolism
Beth Israel Deaconess Medical Center
Center for Life Sciences, 7th floor
330 Brookline Ave
Boston, MA 02215
617-735-3316
617-735-3323