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Angiogenesis

Angiogenesis, the sprouting and proliferation of endothelial cells from pre-existing blood vessels is a biological process on which all growing tissues rely. As an important corollary, angiogenesis may play a pathophysiological role in many diseases, including tumors, diabetic retinopathy and wound healing. Notably anti-angiogenesis therapy has recently emerged as an important adjunct to therapy of certain cancers.

A key focus of the Center for Vascular Biology Research at Beth Israel Deaconess Medical Center is to delineate molecular pathways underlying physiological and pathological angiogenesis, and to identify novel diagnostic and therapeutic targets. Areas of interest include placental growth, tumor angiogenesis, wound repair, retinopathy of prematurity, and neovascularization of ischemic tissue.

Angiogenesis Researcher Faculty

Ruhul Abid, MD, PhD


Research area:
Redox and Signal Transduction in the Endothelium

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Laura Benjamin, PhD


Research area:
Mechanisms of Blood and Lymphatic Angiogenesis

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Harold F. Dvorak, MD


Research area:
Vascular Permeability and Angiogenesis

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Marianne A. Grant, PhD


Research area:
Protein Structure-Function and Biomolecular Recognition

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Elzbieta Kaczmarek PhD


Research area:
P2 Receptor Signaling in Endothelial Cells

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Ananth Karumanchi, MD


Research area:
Pre-eclampsia

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Jack Lawler, PhD


Research area:
Tissue Remodeling and Angiogenesis by Thrombospondins

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Janice A. Nagy, PhD


Research area:
VEGF and Pathological Vascular Phenotype

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Donald R. Senger, PhD


Research area:
Capillary Morphogenesis

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Shou-Ching Shih, PhD


Research area:
Intercellular Communication and Angiogenesis

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Huiyan Zeng, PhD


Research area:
Signaling pathways of Angiogenesis

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Dezheng Zhao, PhD


Research area:
Signaling in Pathogenic Angiogenesis

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Find a Researcher

Contact Information

Nicole Magner, Administrative Assistant
Center for Vascular Biology Research
Beth Israel Deaconess Medical Center
Research North
99 Brookline Avenue
Boston, MA 02215
617-667-0654
info.cvbr@bidmc.harvard.edu