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Arany Publications

Recent Publications 

Recent Reviews

Arany Z.  PGC-1 Coactivators and Skeletal Muscle Adaptations in Health and Disease. Current Opinions in Genetics and Development. 2008. In press.

Arany Z, and Spiegelman BM. PGC-1a and Metabolic Control in Skeletal and Cardiac Muscle. (2008) In: Kumar R, and O'Malley BW, editors. Nuclear Receptor Coregulators and Human Disease. World Scientific Publishing; 2008. Chapter 8: 301-318.

Wagner BK, and Arany Z. (2008) High-throughput real-time PCR for detection of gene expression levels. In: Clemons P, Tollida N, Wagner B, editors. Cell-based Assays in High-Throughput Screening. Humana Press. in press.

Arany Z. High-throughput quantitative real-time PCR. (2008) In: Haines JL, Korf BR, Morton CC, Seidman CE, Seidman JG, Smith DR, editors. Current Protocols in Human Genetics. John Wiley & Sons; 2008. Chapter 11: Unit 11.10.


Recent Original Articles

Arany, Z., S.-Y. Foo, Y. Ma, J. Ruas, A. Bommi-Reddy, G. Girnun, M. Cooper, D. Laznik, J. Chinsomboon, S. Rangwala, K. H. Baek, A. Rosenzweig, and B.M. Spiegelman. (2008) "HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α." Nature. 451: 1008-13.

Arany Z, Wagner BK, Ma Y, Chinsomboon J, Laznik D, and Spiegelman BM. (2008) "Gene expression-based screening identifies microtubule inhibitors as inducers of PGC-1α and oxidative phosphorylation." Proc. Natl. Acad. Sci. USA. 2008; 105: 4721-6.

Arany, Z., N. Lebrasseur, C. Morris, E. Smith, W. Yang, Y. Ma, S. Chin, and B.M. Spiegelman. (2007) "The Transcriptional Coactivator PGC-1β Drives the Formation of Oxidative Type IIX Fibers in Skeletal Muscle." Cell Metabolism, 5: 35-46.

Sandri, M., J. Lin, C. Handschin, W. Yang, Z. Arany, S. H. Lecker, A. L. Goldberg and B. M. Spiegelman (2006) "PGC-1aprotects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription". PNAS, 103:16260-5

Arany, Z., M. Novikov, S. Chin, Y. Ma, A. Rosenzweig, and B. M. Spiegelman (2006) "Transverse aortic constriction leads to accelerated heart failure in mice lacking PGC-1α". PNAS, 103:10086-89.

Arany, Z., H. He, J. Lin, K. Hoyer, C. Handschin, O. Toka, F. Ahmad, T. Matsui, S. Chin, P.-H. Wu, I. I. Rybkin, J. M. Shelton, M. Manieri, S. Cinti, F. J. Schoen, R. Bassel-Duby, A. Rosenzweig, J. S. Ingwall, and B. M. Spiegelman (2005) "Transcriptional coactivator PGC-1acontrols the energy state and contractile function of cardiac muscle". Cell Metabolism, 1: 259-271.