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Selected Recent References

•  Rudders S, Gaspar J, Madore R, Voland C, Grall F, Patel A, Pellacani A, Perrella M, Libermann T, Oettgen P . ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kB to regulate the inducible nitric oxide gene expression. J Biol Chem 2001; Vol. 276; 3302-3309.

•  Dube A, Thai A, Gaspar J, Rudders S, Libermann TA, Iruela-Arispe L, Oettgen P . ELF-1 is a transcriptional regulator of the Tie2 gene during vascular development. Circulation Research. 2001; 88:237-244.

•  Oettgen P. Transcriptional Regulation of Vascular Development. Circulation Research. 2001, 89:380-388.

•  Christensen RA, Fujikawa K, Madore R, Oettgen P , Varticovski L. NERF2, a member of the Ets family of transcription factors, is induced by hypoxia and upregulates the expression of Tie2. J. Cell. Biochem. 2002;85(3):505-15.

•  Gaspar J, Thai S, Voland C, Dube A, Libermann TA, Iruela-Arispe ML, and Oettgen P . Opposing Functions of Ets Factors NERF and ELF-1 in Regulation of Tie Genes During Chicken Blood Vessel Development ATVB 2002;22:1106-1112.

•  Gravallese EM, Pettit AR, Lee R, Madore R, Manning C, Tsay A, Gaspar J, Goldring MB, Goldring SR, Oettgen P Angiopoietin-1 is expressed in the synovium of patients with rheumatoid arthritis and is induced by TNF- a . Ann Rheum Dis. 2003 Feb;62(2):100-7.

•  Laham RJ, Oettgen P . Bone marrow transplantation for the heart: fact or fiction? Lancet. 2003 Jan 4;361(9351):11-2.

•  Flt-1(VEGFR-1)-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids Richard C. Bates, Jeffrey D. Goldsmith, Robin E. Bachelder, Courtney Brown, Masabumi Shibuya, Oettgen P , and Arthur M. Mercurio. 2003 Current Biology

•  Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, Manning C, Voland C, Goldring SR, Goldring MB, Libermann TA, Gravalllese EM, Oettgen P . ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. J Biol Chem. 2004 Jan 8 [Epub ahead of print]

•  Wang H, Fang R, Cho JY, Libermann TA, Oettgen P . Positive and Negative Modulation of the Transcriptional Activity of the ETS Factor ESE-1 through Interaction with p300, CREB-binding Protein, and Ku 70/86. J Biol Chem. 2004 Jun 11;279(24):25241-50

Contact Information

Dr. Peter Oettgen
Cardiovascular Medicine
99 Brookline Avenue
Boston, MA 02215