Electron Microscopy (EM) Core
Provides Services in Electron Microscopy
The EM Core at BIDMC provides service, technical assistance, and instrumentation for electron microscopy techniques.
- Tissue processing for Transmission Electron Microscopy
- Sectioning for Transmission Electron Microscopy
- Ultrastructural analysis and image processing
Work is done on a fee-for-service basis with a graded fee structure.
Priority use is given to BIDMC researchers and priority use and reduced fees are provided to investigators of the Harvard Digestive Diseases Center (due to the NIH-funded Digestive Diseases Center grant).
Equipment in the facility includes:
- JEOL 1400 (photo, right)
- Installed January 2010 and is state-of-the-art.
- High contrast
- Gatan Orius 11 MegaPixel ccd cameras for photodocumentation
- SerialEM, IMOD, and Chimera EM Tomography software.
- Leica Ultracut E Ultramicrotome
- Leica Ultracut S Cryo-Ultramicrotome
- Leica glass knife breaker
- Baltec-Med 020 Vacuum Evaporator
The JEOL1400 transmission electron microscope is available for independent use by any researcher at the BIDMC who receives training by core staff.