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Cardiovascular Division Faculty

Mark JosephsonDr. Mark E. Josephson has served as Chief of the Division of Cardiovascular Medicine since November 2001. A leader in the field of electrophysiology, his research has produced important contributions to the understanding of the mechanisms and substrate of ventricular tachycardia associated with coronary artery disease and the role of EP-guided pharmacologic therapy in treating these disorders. The author of the textbook Clinical Electrophysiology, Josephson also developed the techniques of catheter mapping which currently form the basis for all catheter and surgical ablative techniques to treat arrhythmias. Dr. Josephson's research interests are directed to understanding the pathophysiologic and electrophysiologic substrate for arrhythmias, defining and characterizing reentrant circuits with particular focus on the mechanisms of tachycardia initiation and termination, the mechanism of antiarrhythmic effects of pharmacologic agents, and the development of techniques (both invasive and noninvasive) to predict sudden cardiac death.

AppelbaumDr. Evan Appelbaum is Instructor of Medicine at Harvard Medical School and a member of the Noninvasive Cardiology Section at BIDMC. With a particular interest in cardiovascular magnetic resonance (CMR), his research interests include coronary artery imaging and perfusion assessment using CMR, as well as ventricular remodeling following myocardial infarction.

AroestyDr. Julian Aroesty, Chairman of the Cardiology Executive Advisory Committee, is a veteran clinician in both clinical cardiology and cardiac catheterization. His research interests lie in both clinical cardiology and outcomes analysis, in particular as applied to congestive heart failure, unstable coronary states, intervention, intra-aortic balloon counterpulsation, and pacemaker therapy. Dr. Aroesty is Associate Clinical Professor of Medicine at Harvard Medical School.

ChangDr. James D. Chang joined the Division of Cardiovascular Medicine in 1994, after serving as a cardiology fellow. His studies focus on the intracellular mechanisms of agonist-inducible platelet activation. He is currently investigating the role of phosphoinositide kinases in atherosclerosis and of protein kinase C (PKC) in the inducible expression of the platelet fibrinogen receptor, glycoprotein IIb-IIIa (GPIIb-IIIa).

CutlipDr. Donald Cutlip was named Chief of BIDMC's Cardiac Catheterization Laboratory in 2007. An Associate Professor of Medicine at Harvard Medical School, Dr. Cutlip also serves as Executive Director of Clinical Investigations at the Harvard Clinical Research Institute (HRCI) and Director of the Diabetic Heart Clinic at BIDMC. His research interests include the study of acute reperfusion therapy for myocardial infarction and clinical outcomes after percutaneous coronary intervention.

Dr. Loryn S. Feinberg joined the BIDMC faculty in 2006 after completing the Cardiovascular Disease fellowship program. A clinical cardiologist with a particular interest in women's cardiovascular disease and heart disease in pregnancy, Dr. Feinberg is an Instructor in Medicine at Harvard Medical School.

GelfandDr. Eli Gelfand is Director of Ambulatory Cardiology at BIDMC and concurrentlyserves as Associate Director of the Cardiovascular Training Fellowship, and is also on staff at the Echocardiography Laboratory and the Cardiac MRI Center. Within the fellowship, Dr. Gelfand is responsible for coordinating fellows' education through lectures, curriculum and conferences. Dr. Gelfand has a large and rapidly growing outpatient practice and hosts a weekly Russian Cardiovascular Clinic, where many immigrants from the countries of the former Soviet Union get cardiac care. His clinical interests are in valvular heart disease, as well as new imaging modalities, such as cardiac MRI and three-dimensional echocardiography.

GervinoDr. Ernest Gervino is the Director of the Exercise Testing Laboratory and serves as a consultant for the Harvard Clinical Research Institute as the director of the Exercise Testing Core Lab for both national and international research trials. His interests include the effects of exercise training, diet and behavior modification on the reduction of risk for a second cardiac event following a myocardial infarction, percutaneous transluminal coronary angioplasty and/or coronary artery pass grafting. Dr. Gervino is an Assistant Professor of Medicine at Harvard Medical School.

GibsonDr. C. Michael Gibson is an interventional cardiologist and Director of Core Services at the TIMI (Thrombolysis in Myocardial Infarction) Study Group. An Associate Professor of Medicine at Harvard Medical School, Dr. Gibson's work has focused on the development of statistical and angiographic methodologies to investigate the pathophysiology of coronary artery disease and the efficacy of therapeutic modalities. He directs the angiographic core laboratory and was one of the first investigators to show the disconnect between an open cardiac artery and myocardial damage post PCI.

GoldbergerDr. Ary L. Goldberger is Director of the Marget and H.A. Rey Institute for Nonlinear Dyamics in Physiology and Medicine and Program Director of the NIH/NCRR Research Resource for Complex Signals (www.physionet.org), a national center with the general mission of accelerating new research on complex physiological signals and making data and analytic tools available to help extract "hidden information" in typically nonstationary, nonlinear signals. Dr. Goldberger and his colleagues have pioneered the application of fractals to physiology and methods to quantify the breakdown of fractal scaling as they pertain to aging and disease. Dr. Goldberger is Professor of Medicine at Harvard Medical School. His website, ECG Wave-Maven, is one of the most popular online cardiology educational resources.

Together with the other members of the Division, Dr. Goldberger runs a popular annual course in ECG interpretation. Download brochure.

Dr. Charles Haffajee joined the full time faculty at BIDMC as Director of Device Trials and Cardiac Electrophysiology Network Development. Previously he was Professor of Medicine at Tuft's University.School of Medicine. He completed his medical education at Trinity College (University of Cambridge) and University College Hospital Medical School in London,England. Having completed his Residencies and Cardiology training in London, he began his Cardiac Electro-physiology and Pacing career at University of Massachusetts Medical Center in 1976. His primary interests are in Pacing, Defibrillation, Congestive Heart Failure and Atrial Fibrillation.

HauserDr. Thomas Hauser joined the faculty of Beth Israel Deaconess in 2004 after completing a fellowship in Cardiovascular Magnetic Resonance Imaging at BIDMC. An Assistant Professor of Medicine at Harvard Medical School, Dr. Hauser directs the Division of Nuclear Cardiology. His primary research interest is in the clinical application of advanced methods of cardiovascular imaging.

HoDr. Kalon Ho is Director of Quality Assurance for BIDMC's Division of Cardiovascular Medicine, Chief of Clinical Epidemiology at the Harvard Clinical Research Institute and Assistant Professor of Medicine at Harvard Medical School. He leads BIDMC's effort to track indices of quality and to improve cardiology performance. His research interests include temporal changes in the incidence, prevalence and prognosis of congestive heart failure; methodological issues in the design, management and analyses of clinical trials; and cost-effectiveness of cardiac interventions.

KangDr. Peter M. Kang joined the faculty of BIDMC after completing his Cardiology Fellowship in 1998. He is currently studying the elucidation of the molecular mechanisms involved in cardiac apoptosis, and the contribution of cardiac apoptosis to the progression of heart failure. He is an Assistant Professor of Medicine at Harvard Medical School.

KannamDr. Joseph P. Kannam joined the BIDMC faculty in 1995 and is currently the Chief of Cardiology at the Beth Israel Deaconess Medical Center Needham campus, where the division's ambulatory section has more than 22,000 patient visits per year. An Assistant Professor of Medicine at Harvard Medical School, Dr. Kannam's research interests include determining the role of troponins in the risk stratification of patients, and the examination of practice patterns in the management of coronary disease and preventive cardiology in a large ambulatory cardiology practice.

LahamDr. Roger J. Laham joined the faculty of the Cardiovascular Division in 1996 and currently serves as the Director of Basic Angioplasty Research in addition to his roles in the Section of Interventional Cardiology and the Cardiovascular Angiogenesis Research Center. Dr. Laham is investigating the role of nitric oxide in ischemia and growth-factor induced angiogenesis, as well as novel delivery techniques of growth factors, gene therapy vectors, and autologous myoblasts and stem cells in large animal models. He is an Associate Professor of Medicine at Harvard Medical School.

LeemanDr. David Leeman has a primary interest in interventional cardiovascular medicine, including angioplasty, stenting, atherectomy, intracoronary ultrasound and angioscopy. He is currently the principal investigator of a multicenter trial studying the potential antiatherosclerotic properties of a new ACE inhibitor, using quantitative angiography. An An Assistant Professor of Medicine at Harvard Medical School, Dr. Leeman's interests also include cholesterol management and research on the regression of coronary artery disease with cholesterol-lowering agents.

LewisDr. Stanley M. Lewis is an Associate Professor of Medicine at Harvard Medical School and serves as the Vice President of Network Development initiatives and vice president of the physicians' organization at BIDMC. Actively involved in the initiation of new clinical activities within the division of cardiology, Dr. Lewis's research interests include risk assessment in the preoperative patient and the spectrum of CAD in the octogenarian.

ManningDr. Warren J. Manning joined the BIDMC Cardiovascular faculty in 1989 and established the Cardiac MR Center in 1995 as a joint effort of the Cardiovascular Division and Department of Radiology. Since 2000, he has also served as the Section Chief of Noninvasive Cardiac Imaging. His research interests include the development and application of cardiovascular magnetic resonance (CMR), including coronary artery imaging, imaging of subclinical atherosclerosis in large populations, valvular heart disease, cardiomyopathies, and non-cardiac pathology identified during CMR examinations; and echocardiography, including atrial fibrillation, atrial function, and valvular heart disease. In addition to his research and administrative responsibilities, he attends in the Echocardiography Laboratory, Cardiac MR Center, and on the consult and step-down unit clinical services. Dr. Manning is a Professor of Medicine and Professor of Radiology at Harvard Medical School.

MarkisDr. John E. Markis is the Director of the Electrocardiography Laboratory. His research interests include cost-effectiveness studies in the therapy of coronary artery disease and thrombolytic therapy of acute myocardial infarction and pulmonary embolism. He is Assistant Clinical Professor of Medicine at Harvard Medical School.

MittlemanDr. Murray A. Mittleman is an Associate Professor of Medicine at Harvard Medical School and is currently Chair of the Master of Public Health program at the Harvard School of Public Health. Director of Cardiovascular Epidemiology at the Institute for Prevention of Cardiovascular Disease at BIDMC, his applied research is in the area of environmental and behavioral determinants of the onset of acute cardiovascular events, including myocardial infarction, arrhythmias, stroke and congestive heart failure decompensation.

NezafetDr. Reza Nezafat joined the faculty of Cardiovascular Division in 2006 and currently is Associate Scientific Director of Cardiac MR Center. Dr. Nezafat completed his training at Johns Hopkins School of Medicine and National Institute of Health in Biomedical Engineering prior to joining Harvard Medical School. Dr. Nezafat research is to develop and apply new non-invasive methods in magnetic resonance imaging to guide therapy in cardiovascular disease. Dr. Nezafat is the recipient of 2007 W.S. Moore Young Investigator Award of International Society for Magnetic Resonance in Medicine.

OettgenDr. J. Peter Oettgen is the Director of Preventive Cardiology and the Cardiovascular Health and Lipid Center. Dr. Oettgen is currently establishing a genomics core for patients with lipid disorders and those with angiographically defined coronary heart disease in order to determine the genetic causes of dyslipidemias and coronary heart disease. An Associate Professor of Medicine at Harvard Medical School, Dr. Oettgen directs a basic research laboratory at the Harvard Institutes of Medicine.

LeemanDr. David O'Halloran is an Instructor in Medicine at Harvard Medical School. He joined the faculty at BIDMC in 2007 after completing residency at Massachusetts General Hospital and fellowship at BIDMC. He has a busy outpatient practice and is a specialist in noninvasive imaging and a popular teacher in the clinic and CCU.

PapageorgiouDr. Panos Papageorgiou is the Director of the Pacemaker and ICD Clinic and the Clinical Director of the Arrhythmia Monitoring Laboratory and is a staff electrophysiologist of the Harvard-Thorndike Institute of Electrophysiology. Dr. Papageorgiou's basic research includes exploration of the role of the myocardial chloride/bicarbonate exchanger in mediating enhanced impulse formation and potential arrhythmias associated with ischemia-reperfusion. He is an Assistant Professor of Medicine at Harvard Medical School.

ParkerDr. J. Anthony Parker is a member of the Division of Nuclear Medicine whose current interests include therapy with unsealed sources, the development of procedure guidelines, internet teaching tools and cardiovascular applications of positron emission tomography. Dr. Parker is Associate Professor of Radiology at Harvard Medical School.

PaulinDr. Sven Paulin is the Miriam H. Stoneman Professor of Radiology Emeritus at Harvard Medical School and Radiologist-in-Chief Emeritus at BIDMC. He has made significant contributions to the development of such angiographic procedures as transseptal angiocardiography, retrograde angiocardiography, nonselective and selective coronary angiography, pulmonary angiography and phlebography of the lower extremities.

Duane PintoDr. Duane S. Pinto is Director of the Cardiovascular Disease Fellowship Training Program. Dr. Pinto completed his residency, chief residency, general cardiology fellowship and interventional cardiology fellowship at BIDMC. He is an Assistant Clinical Professor of Medicine at Harvard Medical School. He maintains a general cardiology outpatient practice and his research interests include evaluation of anticoagulation strategies for acute coronary syndromes as well as the development of approaches aimed at improving outcomes during and after myocardial infarction.

Dr. Jeffrey Popma joined the interventional section in 2009. He is an Associate Professor of Medicine at Harvard Medical School. He is an accomplished interventional cardiologist with extensive clinical trial experience. His main academic interests involve angiographic evaluation of new technology and his group has served as the core laboratory for numerous new technologies including those for carotid and coronary applications. He is the co-principal investigator of the Percutaneous Aortic Valve Intervention Study (PAVIS) utilizing the CoreValve® Revalving® technology.

Dr. Carl Rasmussen is a staff cardiologist at BIDMC and an Instructor of Medicine at Harvard Medical School. His clinical expertise is in the diagnosis and management of rhythm disturbances, utilizing both invasive and noninvasive



RosenzweigDr. Anthony Rosenzweig is the Director of Cardiovascular Research and Associate Chief of the Divison of Cardiovascular Medicine. Dr. Rosenzweig's laboratory has investigated the pathways controlling cardiomyocyte survival and growth. His work investigating the intersection of these pro-survival signaling pathways with those controlling cardiac metabolism is funded by an international research grant from the LeDucq Foundation Network of Research Excellence, for which Dr. Rosenzweig serves as the American Coordinator. He serves as an Associate Editor of The New England Journal of Medicine and is an Executive Board member of the Harvard Stem Cell Institute.

SaffitzDr. Jeffrey E. Saffitz is Chairman of the Department of Pathology at BIDMC. Dr. Saffitz has a longstanding interest in electrical coupling via gap junctions in cardiac myocytes, has characterized the roles of the individual cardiac connexins in impulse propagation, and has defined the mechanisms by which remodeling of gap junctions in the diseased heart contributes to the pathogenesis of sudden death. He is the Mallinckrodt Professor of Pathology at Harvard Medical School.

ShubrooksDr. Samuel Shubrooks is Codirector of the Cardiac Catheterization Laboratory and an Associate Professor of Medicine at Harvard Medical School. Dr. Shubrooks' clinical and research interests include interventional cardiology, and aortic and mitral valvuloplasty.

ShvilkinDr. Alexei Shvilkin is an Instructor in Medicine at Harvard Medical School and the Co-Director of Ambulatory Monitoring at BIDMC. He is an electrophysiologist at both BIDMC and South Shore Hospital.

VerrierDr. Richard Verrier is the Director of the Institute for Prevention of Cardiovascular Disease and Associate Professor of Medicine at Harvard Medical School. Over the past two decades, his research has focused on neural control of heart rhythm with particular reference to the problem of sudden cardiac death. He has conducted studies ranging from detailed investigations of central and peripheral nervous system mechanisms to explorations of the integrated influences of the clinically relevant behavioral states of anger, fear and sleep. Most recently, Dr. Verrier has developed novel percutaneous means for accessing the normal pericardial space for targeted drug delivery and demonstrated that T-wave alternans magnitude provides a noninvasive index of vulnerability to lethal cardiac arrhythmias in human subjects.

Dr. Francine K. Welty is Associate Professor of Medicine at Harvard Medical School and Principal Investigator and Director of the NHLBI Specialized Center of Clinically Oriented Research in Vascular Injury, Repair and Remodeling. A second major research interest of Dr. Welty's is gene mapping for Type 2 diabetes, hypertension, cardiovascular risk genes and other complex traits among the Ohio Amish population. Dr. Welty's NIH-funded research includes use of stable isotopes to investigate the effect of apoB and apoA-I mutations and statin drugs on lipid metabolism. Her clinical focus is on preventive cardiology and heart disease in women, and as a recipient of the Women's Center of Excellence grant from Harvard Medical School, Dr. Welty is examining the effect of soy on lipid levels, inflammatory markers of atherosclerosis, adhesion molecules, brachial artery activity, bone density and menopausal symptoms in women.

ZimetbaumDr. Peter Zimetbaum is Associate Professor of Medicine at Harvard Medical School and Director of the Morse Cardiac Care Unit and clinical director of Cardiac Electrophysiology. He is also Director of the ECG and Arrhythmia Core Laboratory at the Harvard Clinical Research Institute. Director of the BIDMC Atrial Fibrillation Clinic, Dr. Zimetbaum is also principal investigator of a national multicenter registry of atrial fibrillation.

Contact Information

Cardiovascular Disease Fellowship Program
Beth Israel Deaconess Medical Center
185 Pilgrim Road
Boston, MA 02215
617-632-7828
617-632-7536
ecabral1@bidmc.harvard.edu