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Double-Edged Sword: Killing Cancer Cells can also Drive Tumor Growth

dipakpanigrahyheadshotA team of researchers, including experts at BIDMC,
has found that dead and dying cancer cells caused by chemotherapy and other targeted cancer therapies
can, in turn, result in aggressive tumor growth.

“Conventional cancer therapy designed to kill tumor cells is inherently a double-edged sword,” said senior author Dipak Panigrahy, MD, scientist at the Cancer Center
at BIDMC.

megan-sulciner-Headshotv2However, in a follow-up set of experiments, the researchers found a novel approach to preventing cancer resurgence by introducing a class of naturally occuring anti-inflammatories called resolvins. These resolvins may also be an effective component of treatment when added to existing chemotherapy.

Learn more about this new research and the Cancer Center at BIDMC here.

Pictured: senior author Dipak Panigrahy, MD, and co-author Megan Sulciner, MD