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Warren J. Manning, MD

Photograph of Dr. Warren Manning


  • Chief, Non-Invasive Cardiac Imaging
  • Professor of Medicine, Harvard Medical School
  • Professor of Radiology, Harvard Medical School


Dr. Warren Manning, currently Section Chief of Non-invasive Cardiac Imaging in Cardiology, and Professor of Medicine and Radiology, Harvard Medical School, received his M.D degree from Harvard Medical School and did his residency in Internal Medicine and subspecialty training in Cardiology at the former Beth Israel Hospital in Boston. His academic interest is non-invasive cardiac imaging and his areas of expertise include cardiac MRI and cardiac ultrasound/echocardiography.


Recent Publications:

  • Gelfand EV, Haffajee JA, Hauser TH, Yeon SB, Goepfert L, Kissinger KV, Delatorre R, Manning WJ. Predictors of preserved left ventricular systolic function after surgery for chronic organic mitral regurgitation: a prospective study. J Heart Valve Dis 2010;19:43-50.
  • Meng J, Peters DC, Hsing J, Chuang M, Chan J, Fish A, Josephson ME, Manning WJ. Late gadolinium enhancement of the esophagus is common on cardiovascular magnetic resonance several months after pulmonary vein isolation: preliminary observations. Pacing Clin Electrophysiol 2010;33:661-6..
  • Han Y, Chan J, Haber I, Peters DC, Zimetbaum PJ, Manning WJ, Yeon SB. Circumferential myocardial strain in cardiomyopathy with and without left bundle branch block. J Cardiovasc Magn Reson 2010; 12:2.
  • Taclas JE, Nezafat R, Wylie JV, Josephson ME, Hsing J, Manning WJ, Peters DC. Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance. Pacing Clin Electrophysiol 2010;7:489-96.
  • Harrigan CJ, Peters DC, Gibson CM, Maron BJ, Manning WJ, Maron MS, Appelbaum E. Hypertrophic cardiomyopathy: quantification of late gadolinium enhancement with contrast-enhanced cardiovascular MR imaging. Radiology 2011;258:128-33.
  • Stoeck CT, Hu P, Peters DC, Kissinger KV, Goddu B, Goepfert L, Ngo L, Manning WJ, Kozerke S, Nezafat R. Optimization of on-resonant magnetization transfer contrast in coronary vein MRI. Magn Reson Med 2010;64:1849-54.
  • Hu P, Chuang ML, Kissinger KV, Goddu B, Goepfert LA, Rofsky NM, Manning WJ, Nezafat R. Non-contrast enhanced pulmonary vein MRI with a spatially selective slab inversion preparation sequence. Magn Reson Med 2010;63:530-6.
  • Hu P, Chuang ML, Ngo LH, Stoeck CT, Peters DC, Kissinger KV, Goddu B, Goepfert LA, Manning WJ, Nezafat R. Coronary MR imaging: Effect of timing and dose of isosorbide dinitrate administration. Radiology 2010;254:401-9.
  • Velagaleti RS, Gona P, Chuang ML, Salton CJ, Fox CS, Blease SJ, Yeon SB, Manning WJ, O'Donnell CJ. Relations of insulin resistance and glycemic abnormalities to cardiovascular magnetic resonance measures of cardiac structure and function: the Framingham Heart Study. Circulation Imaging 2010;3:257-63.
  • Han Y, Peters DC, Kissinger KV, Goddu B, Yeon SB, Manning WJ, Nezafat R. Evaluation of papillary muscle function using cardiovascular magnetic resonance imaging in mitral valve prolapse. Am J Cardiol 2010;106:243-8.
  • Olivotto I, Maron BJ, Appelbaum E, Harrigan CJ, Salton C, Gibson CM, Udelson JE, O'Donnell C Lesser JR, Manning WJ, Maron MS,. Spectrum and clinical significance of systolic function and myocardial fibrosis assessed by cardiovascular magnetic resonance in hypertrophic cardiomyopathy. Am J Cardiol 2010;106:261-7.
  • Pride YB, Giuseffi JL, Mohanavelu S, Harrigan CJ, Manning WJ, Gibson CM, Appelbaum E. Relation between infarct size in ST-segment elevation myocardial infarction treated successfully by percutaneous coronary intervention and left ventricular ejection three months after the infarct. Am J Cardiol 2010;106:635-40.
  • Jefferson AL, Himali JJ, Beiser AS, Au R, Massaro JM, Seshadri S, Gona P, Salton CJ, DeCarli C, O'Donnell CJ, Benjamin EJ, Wolf PA, Manning WJ. Cardiac index is associated with brain aging: The Framingham Heart Study Circulation 2010;122:690-7.
  • Hundley WG, Bluemke DA, Finn JP, Flamm SD, Fogel MA, Friedrich MG, Ho VB, Jerosch-Herold M, Kramer CM, Manning WJ, Patel M, Pohost GM, Stillman AE, White RD, Woodard PK. ACCF/ACR/AHA/NASCI/SCMR 2010 Expert consensus document on cardiovascular magnetic resonance. A report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents. J Am Coll Cardiol 2010;55:2614-62.
  • Parker MW, Mittleman MA, Waksmonski CA, Sanders G, Riley MF, Douglas PS, Manning WJ. Pulmonary hypertension and long-term mortality in aortic and mitral regurgitation. Am J Med 2010;123:1043-8.
  • Delling FH, Kang LL, Yeon SB, Kissinger KV, Goddu B, Manning WJ, Han Y. CMR predictors of mitral regurgitation in mitral valve prolapse. J Am Coll Cardiol Imaging 2010;3:1037-45.
  • Robich MP, Chu LM, Chaudray M, Nezafat R, Han Y, Clements RT, Laham RJ, Manning WJ, Coady MA, Sellke FW. Anti-angiogenic effect of resveratrol in a swine model of metabolic syndrome. Surgery 2010;148:453-62.
  • Douglas PS, Garcia MJ, Haines DE, Lai WW, Manning WJ, Patel AR, Picard MH, Polk DM, Ragosta M, Ward RP, Weiner RB. ACCF/ASE/ACCP/AHA/ASNC/HFSA/HRS/SCAI/SCCT/SCMR 2010 Appropriate use criteria for echocardiography. J Am Coll Cardiol 2011;57:1126-66.
  • Hu P, Stoeck CT, Smink J, Peters DC, Ngo L, Goddu B, Kissinger KV, Goepfert LA, Chan J, Hauser TH, Rofsky NM, Manning WJ, Nezafat R. Non-contrast SSFP pulmonary vein magnetic resonance angiography: impact of off-resonance and flow J Magn Reson Imaging 2010;32:1255-61.
  • Gerretsen S, Kooi ME, Kessels AG, Schalla S, Katoh M, van der Geest RJ, Manning WJ, Waltenberger J, van Engelshoven J, Botnar RM, Leiner T. Visualization of coronary wall atherosclerosis in asymptomatic subjects and patients with coronary artery disease using magnetic resonance imaging. PLoS One 2010 5(9):e12998.
  • Cardiovascular Magnetic Resonance 2nd ed. Manning WJ and Pennell DJ, eds. Philadelphia, Saunders/Elsevier, Philadelphia, MA. 2010.
  • A Guide to Echocardiography.Silverman DI and Manning WJ. Jones and Bartlett, Boston, MA 2010.
  • Santelli C, Nezafat R, Goddu B, Manning WJ, Smink J, Kozerke S, Peters DC. Respiratory bellows revisited for motion compensation: preliminary experience for cardiovascular MR. Magn Reson Med 2011;65:1097-102.
  • Hu P, Chan J, Ngo LH, Smink J, Goddu B, Kissinger KV, Goepfert L, Hauser TH, Rofsky NM, Manning WJ, Nezafat R. Contrast-enhanced whole-heart coronary MRI with bolus infusion of gadobenate dimeglumine at 1.5T. Magn Resonan Med 2011;65:392-8.
  • Tsao CW, Gona P, Salton C, Danias PG, Blease S, Hoffmann U, Fox CS, Albert M, Levy D, O'Donnell CJ, Manning WJ, Yeon SB. Subclinical and clinical correlates of left ventricular wall motion abnormalities in the community. Am J Cardiol 2011;107:949-55.
  • Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free-breathing left atrium late gadolinium enhancement. Mag Resonan in Med 2011 (in press).
  • Khosa F, Romney BP, Costa DN, Rofsky NM, Manning WJ. Prevalence of non-cardiac findings on clinical cardiovascular magnetic resonance imging. Am J Roentgenol 2011;196:W380-6.
  • Thadhani R, Appelbaum E, Chang Y, Pritchett Y, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata J, Thompson T, Audhya P, Andress D, Zhang W, Ye J, Packham D, Singh B, Zehnder D, Manning WJ, Pachika A, Solomon SD. Vitamin D receptor activation and left ventricular hypertrophy in advanced kidney disease. Am J Nephrol 2011;33:139-49.
  • Pritchett Y, Jemiai Y, Chang Y, Bhan I, Agarwal R, Zoccali C, Wanner C, Lloyd-Jones D, Cannata-Andia JB, Thompson T, Appelbaum E, Audhya P, Andress D, Zhang W, Solomon S, Manning WJ, Thadhani R. A Group Sequential, Information-based Sample Size Re-estimation Design of the PRIMO (Paricalcitol capsules benefits in Renal failure Induced cardiac MOrbidity in chronic kidney disease) study. 2011 (in press).
  • Akcakaya M, Hu P, Chuang ML, Hauser TH, Ngo LH, Manning WJ, Tarokh V, Nezafat R. Accelerated non-contrast enhanced pulmonary vein MRA with distributed compressed sensing. J Magn Reson Imaging 2011 (in press).
  • Moghari MH, Akcakaya M, O'Connor A, Basha T, Casanova M, Goepfert L, Kissinger KV, Goddu B, Chuang M, Tarokh V, Manning WJ, Nezafat R. COmpressed-Sensing MOtion compensation (COSMO): A joint prospective-retrospective respiratory navigatory for coronary MRI. Magn Resonan Med 2011 (in press).
  • Rahimi AR, York M, Gheewala N, Markson L, Hauser TH, Manning WJ. Trends in outpatient transthoracic echocardiography: Impact of appropriateness criteria publication. Am J Med 2011 (in press).
  • Maron MS, Olivotto I, Harrigan C, Appelbaum E, Gibson CM, Lesser JR, Haas TS, Udelson JE, Manning WJ, Maron BJ. Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotype expression of hypertrophic cardiomyopathy. Circulation 2011 (in press).
  • Akcakaya M, Nam S, Hu P, Moghari MH, Ngo LH, Tarokh V, Manning WJ, Nezafat R. Compressed sensing with wavelet domain dependencies for coronary MRI: a retrospective study. IEEE Trans Med Imaging 2011;30:1090-9.
  • Robich MP, Osipov RM, Chu LM, Han Y, Feng J, Nezafat R, Clements RT, Manning WJ, Sellke FW. Resveratrol modifies risk factors for coronary artery disease in a swine with metabolic syndrome and myocardial ischemia. Eur J Pharmacol 2011 (in press).