beth israel deaconess medical center a harvard medical school teaching hospital

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Signs and Symptoms

Symptoms Develop Slowly

Symptoms of mitral valve regurgitation typically develop slowly. You may have the condition for years, even decades, before experiencing symptoms. Sometimes, the symptoms may come on quickly, however.


Symptoms may include:

  • Chronic, progressive fatigue
  • Shortness of breath
  • Worsening shortness of breath when you lie down
  • Atrial fibrillation (mostly in people with long-standing mitral valve regurgitation)
  • Lightheadedness
  • Cough, especially at night or when lying down
  • Swollen feet or ankles
  • Heart murmur


Complications of mitral valve regurgitation can include:

  • Heart failure
  • Atrial fibrillation
  • Endocarditis
  • Pulmonary hypertension

Contact Information

Cardiovascular Medicine
Division of the CardioVascular Institute
Beth Israel Deaconess Medical Center
330 Brookline Avenue
Boston, MA 02215