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Advancing GI Interventional Care

In the BIDMC Center for Advanced Endoscopy, our gastroenterologists are involved in the development of novel endoscopic technologies and protocols to help manage a large variety of gastrointestinal diseases.

Pioneers in Gastroesophageal Reflux Disease and Barretts Esophagus

Ram Chuttani, M.D., and Douglas Pleskow, M.D., internationally acknowledged leaders in endoscopy, are pioneering innovative treatments for gastroesophageal reflux disease and Barretts esophagus, a pre-cancerous condition of the esophagus. Their endoscopic Plicator® procedure offered superb control of GERD in properly selected patients. They are currently pioneering novel endoscopic procedures for Barretts esophagus. These include narrow band imaging and confocal microscopy for early diagnosis of dysplasia/cancer and BARRx radiofrequency ablation and Cryotherapy for treatment.

Cancer Therapies

 Novel enteral stent procedures help manage malignant gastric outlet obstruction and malignant colonic obstruction. Our Advanced Endoscopy team works closely with medical and surgical oncologists to provide care to patients with gastrointestinal cancers.

Barrett's esophagus

BIDMC was also the first in New England to offer BARRx therapy for Barrett's esophagus, a cutting-edge approach using radiofrequency ablation against pre-cancerous mucosa. The Center for Advanced Endoscopy also offer cryotherapy and endomucosal resection techniques for the treatment of Barrett's with high-grade dysplasia and esophageal cancer.

Pancreatocobiliary diseases

BIDMC has long been at the forefront of endoscopic management of pancreatocobiliary diseases, ranging from biliary stones and bile duct strictures, to chronic pancreatitis and pancreatic cancer. For patients with pancreatic conditions, there is robust collaboration between physicians in the Center for Advanced Endoscopy, and BIDMC's renowned medical pancreatologists and pancreas surgeons, with whom we provide comprehensive care to every patient using a team-centered approach. We also collaborate extensively with the world-class Liver Center at Beth Israel Deaconess, to care for patients with complex biliary disorders, and for patients before and after liver transplantation.


Physicians at the Center for Advanced Endoscopy at BIDMC are committed to providing the highest quality and safest care for our patients. A major part of our commitment is our ongoing research in quality and safety in advanced endoscopy. Our anesthesiology team has particular expertise in advanced methods for safe endoscopic sedation, and our gastroenterologists and anesthesiologists have published and presented widely on patient safety and quality measures.


A selection of recent publications by members our group are listed below:

Large Balloon Dilation vs. Mechanical Lithotripsy for the Management of Large Bile Duct Stones: A Prospective Randomized Study. Stefanidis G, Viazis N, Pleskow D, Manolakopoulos S, Theocharis L, Christodoulou C, Kotsikoros N, Giannousis J, Sgouros S, Rodias M, Katsikani A, Chuttani R. . Am J Gastroenterol. 2010 Nov 2.

Endoscopic radiofrequency ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trial. Fleischer DE, Overholt BF, Sharma VK, Reymunde A, Kimmey MB, Chuttani R, Chang KJ, Muthasamy R, Lightdale CJ, Santiago N, Pleskow DK, Dean PJ, Wang KK. Endoscopy. 2010 Oct;42(10):781-9. Epub 2010 Sep 20.

Efficacy of a prototype endoscope with two deflecting working channels for endoscopic submucosal dissection: a prospective, comparative, ex vivo study.Lee SH, Gromski MA, Derevianko A, Jones DB, Pleskow DK, Sawhney M, Chuttani R, Matthes K. Gastrointest Endosc. 2010 Jul;72(1):155-60. Epub 2010 May 20.

Multispectral scanning during endoscopy guides biopsy of dysplasia in Barrett's esophagus. Qiu L, Pleskow DK, Chuttani R, Vitkin E, Leyden J, Ozden N, Itani S, Guo L, Sacks A, Goldsmith JD, Modell MD, Hanlon EB, Itzkan I, Perelman LT. Nat Med. 2010 May;16(5):603-6, 1p following 606. Epub 2010 Apr 11.

Diagnostic imaging of esophageal epithelium with clinical endoscopic polarized scanning spectroscopy instrument. Qiu L, Chuttani R, Zhang S, Feng J, Itani S, Fang H, Pleskow D, Sawhney MS, Salahuddin S, Modell MD, Vitkin E, Hanlon EB, Itzkan I, Perelman LT. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1997-2000.